CAS Number59338-87-3
SynonymsN-[(1-Allyl-2-pyrrolidinyl)methyl]-5-methoxy-1H-benzotriazole-6-carboxamide hydrochloride (1:1); N-[(1-Allylpyrrolidin-2-yl)methyl]-6-methoxy-1H-benzotriazole-5-carboxamide hydrochloride (1:1); Alizapride HCl; 6-methoxy-N-[(1-prop-2-enylpyrrolidin-2-yl)methyl]-2H-benzotriazole-5-carboxamide,hydrochloride
Molecular FormulaC16H22ClN5O2
Molecular Weight351.831
Purity98.00%
Density1.224 g/cm3
Boiling Point580.3ºC at 760 mmHg
Melting Point206-208°
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 59338-87-3 |
| Catalog No. | 2A-9045164 |
| Chinese Name | 盐酸阿立必利 |
| Synonyms | N-[(1-Allyl-2-pyrrolidinyl)methyl]-5-methoxy-1H-benzotriazole-6-carboxamide hydrochloride (1:1); N-[(1-Allylpyrrolidin-2-yl)methyl]-6-methoxy-1H-benzotriazole-5-carboxamide hydrochloride (1:1); Alizapride HCl; 6-methoxy-N-[(1-prop-2-enylpyrrolidin-2-yl)methyl]-2H-benzotriazole-5-carboxamide,hydrochloride |
| Molecular Formula | C16H22ClN5O2 |
| Molecular Weight | 351.831 |
| Purity | 98.00 |
| Density | 1.224 g/cm3 |
| Boiling Point | 580.3ºC at 760 mmHg |
| Melting Point | 206-208° |
| Storage Condition | room temperature, dry |
| Application | Alizapride hydrochloride is a dopamine receptor antagonist with prokinetic and antiemetic effects and may also be used to treat nausea and vomiting, including postoperative nausea and vomiting. |
| HTC | 2933990090 |
| PubChem ID | 16574300 |
| SMILES | C=CCN1CCCC1CNC(=O)c1cc2n[nH]nc2cc1OC.Cl |
| InChI | InChI=1S/C16H21N5O2.ClH/c1-3-6-21-7-4-5-11(21)10-17-16(22)12-8-13-14(19-20-18-13)9-15(12)23-2;/h3,8-9,11H,1,4-7,10H2,2H3,(H,17,22)(H,18,19,20);1H |
| InChI Key | BRECEDGYMYXGNF-UHFFFAOYSA-N |
| Use of | Alizapride hydrochloride is a dopamine receptor antagonist with prokinetic and antiemetic effects which can also be used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. Properties Name N-((1-Allylpyrrolidin-2-yl)methyl)-6-methoxy-1H-benzo[d][1,2,3]triazole-5-carboxamide hydrochloride Synonym More Synonyms alizapride hydrochloride Biological Activity Description Alizapride hydrochloride is a dopamine receptor antagonist with prokinetic and antiemetic effects which can also be used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. Related Catalog Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Cancer Research Areas >> Neurological Disease Dopamine receptor[1] References [1]. Bleiberg H, et al. Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial. Cancer Chemother Pharmacol. 1988;22(4):316-20. Chemical & Physical Properties Exact Mass 351.146210 PSA 83.14000 LogP 2.47750 InChIKey BRECEDGYMYXGNF-UHFFFAOYSA-N Safety Information HS Code 2933990090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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