CAS Number56512-49-3
SynonymsEINECS 260-235-1; 4-[[4-(dimethylamino)phenyl]diazenyl]benzenesulfonyl chloride; MFCD00007444
Molecular Formula(CH3)2NC6H4N=NC6H4SO2Cl
Molecular Weight323.80
Purity98.00%
Density1.29 g/cm3
Boiling Point483.6ºC at 760 mmHg
Melting Point185 °C (dec.)(lit.)
AppearanceRed crystal powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 56512-49-3 |
| Catalog No. | 2A-9044642 |
| Chinese Name | 4-二甲胺基苯基偶氮苯磺酰氯 |
| Synonyms | EINECS 260-235-1; 4-[[4-(dimethylamino)phenyl]diazenyl]benzenesulfonyl chloride; MFCD00007444 |
| Molecular Formula | (CH3)2NC6H4N=NC6H4SO2Cl |
| Molecular Weight | 323.80 |
| Purity | 98.00 |
| Density | 1.29 g/cm3 |
| Boiling Point | 483.6ºC at 760 mmHg |
| Melting Point | 185 °C (dec.)(lit.) |
| Appearance | Red crystal powder |
| Water Solubility | DMF: soluble |
| Storage Condition | Sealed, store at -20 ºC |
| Packaging | II |
| Application | Dabsyl chloride is an amine derivatizing agent that produces a stable product that can be easily monitored spectrophotometrically at 460 nm; Dabsyl chloride can also be used to label amino acids. |
| HTC | 2927000090 |
| PubChem ID | 6395113 |
| SMILES | CN(C)c1ccc(N=Nc2ccc(S(=O)(=O)Cl)cc2)cc1 |
| InChI | InChI=1S/C14H14ClN3O2S/c1-18(2)13-7-3-11(4-8-13)16-17-12-5-9-14(10-6-12)21(15,19)20/h3-10H,1-2H3 |
| InChI Key | VTVWTPGLLAELLI-UHFFFAOYSA-N |
| Hazard Symbols | 8 |
| Bioactivity | Dabsyl chloride is an amine derivatizing agent, able to give rise to stable products that can be easily monitored spectrophotometrically at 460 nm; Dabsyl chloride also used for labeling amino acids. Related Catalog Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others In Vitro Dabsyl chloride can give rise to mono-Dabsyl and bis-Dabsyl derivatives in the presence of multiple amino groups. Furthermore with respect to OPA derivatization, Dabsyl chloride can react with primary and also with secondary amines[1]. Cell Assay Selected mouse brain samples from either cortical or striatal regions (100 mg wet weight) and neuroblastoma cells (SH-SY5Y) pellet derived from 25 cm2 flask are treated with 500 μL of 0.1 M HCl containing 0.2% TDGA, sonicated for 10 min (only for brain tissue), and then centrifuged at 14000 g for 30 min. The supernatant is freeze-dried. 50 μL of reaction buffer and 100 μL of 15 mM Dabsyl chloride are added to the tube and derivatized. References [1]. Francioso A, et al. HPLC Determination of Bioactive Sulfur Compounds, Amino Acids and Biogenic Amines in Biological Specimens. Adv Exp Med Biol. 2017;975:535-549. Chemical & Physical Properties Density 1.29 g/cm3 Boiling Point 483.6ºC at 760 mmHg Melting Point 185 °C (dec.)(lit.) Molecular Formula C14H14ClN3O2S Molecular Weight 323.79800 Flash Point 246.3ºC Exact Mass 323.05000 PSA 70.48000 LogP 5.17630 Index of Refraction 1.607 InChIKey VTVWTPGLLAELLI-UHFFFAOYSA-N SMILES CN(C)c1ccc(N=Nc2ccc(S(=O)(=O)Cl)cc2)cc1 Storage condition −20°C Water Solubility DMF: soluble |
| Use of | Dabsyl chloride is an amine derivatizing agent, able to give rise to stable products that can be easily monitored spectrophotometrically at 460 nm; Dabsyl chloride also used for labeling amino acids. Properties Articles31 Name dabsyl chloride Synonym More Synonyms Dabsyl chloride Biological Activity Description Dabsyl chloride is an amine derivatizing agent, able to give rise to stable products that can be easily monitored spectrophotometrically at 460 nm; Dabsyl chloride also used for labeling amino acids. Related Catalog Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others In Vitro Dabsyl chloride can give rise to mono-Dabsyl and bis-Dabsyl derivatives in the presence of multiple amino groups. Furthermore with respect to OPA derivatization, Dabsyl chloride can react with primary and also with secondary amines[1]. References [1]. Francioso A, et al. HPLC Determination of Bioactive Sulfur Compounds, Amino Acids and Biogenic Amines in Biological Specimens. Adv Exp Med Biol. 2017;975:535-549. Chemical & Physical Properties Exact Mass 323.05000 PSA 70.48000 LogP 5.17630 Index of Refraction 1.607 InChIKey VTVWTPGLLAELLI-UHFFFAOYSA-N Water Solubility DMF: soluble |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 30.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Danger Regulations: 3261 International Maritime Transport Danger Regulations: 3261 International Air Transport Danger Regulations: 3261 14.2 United Nations shipping name European Land Transport Dangerous Regulations: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S. (p-[[4- (Dimethylamino)phenyl]azo]benzenesulphonyl chloride) International Maritime Dangerous Regulations: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S. (p-[[4- (Dimethylamino)phenyl]azo]benzenesulphonyl chloride) International air transport hazard regulations: Corrosive solid, acidic, organic, n.o.s. (p-[[4-(Dimethylamino)phenyl]azo]benzenesulphonyl chloride) 14.3 Transport hazard categories European Dangerous Regulations for land transport: 8 International Dangerous Regulations for sea transport: 8 International Dangerous Regulations for air transport: 8 14.4 Package group European Dangerous Regulations for land transport: II International Dangerous Regulations for sea transport: II International Dangerous Regulations for air transport: II 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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