| Chemical & Physical Properties | |
|---|---|
| CAS Number | 53943-88-7 |
| Catalog No. | 2A-9044089 |
| Chinese Name | 来托司坦 |
| Synonyms | Viscotiol; Letosteine; Letosteinum; Letosteina |
| Molecular Formula | C10H17O4N1S2 |
| Molecular Weight | 279.38 |
| Purity | 98.00 |
| Density | 1.284 g/cm3 |
| Boiling Point | 470ºC at 760 mmHg |
| Melting Point | 142ºC |
| Appearance | White crystalline powder |
| Storage Condition | Room temperature, sealed, dry |
| Application | Lestin is an orally active, effective and safe expectorant. Lestin dissolves bronchial mucus, reduces respiratory tract inflammation symptoms, and restores lung gas exchange and natural defense mechan |
| HTC | 2934999090 |
| PubChem ID | 8192289 |
| MDL Number | MFCD00867663 |
| SMILES | S1C(NC(C1)C(=O)O)CCSCC(=O)OCC |
| InChI | 1S/C10H17NO4S2/c1-2-15-9(12)6-16-4-3-8-11-7(5-17-8)10(13)14/h7-8,11H,2-6H2,1H3,(H,13,14) |
| InChI Key | IKOCLISPVJZJEA-UHFFFAOYSA-N |
| NACRES Code | NA.21 |
| UNSPSC | 12352106 |
| MSDS | msds/44089_1_53943_88_7.pdf |
| Use of | Letosteine is an orally active, potent and safe expectorant. Letosteine dissolves bronchial mucus and reduces respiratory inflammation symptoms, and restores gas exchanges and natural defense mechanisms in the lung. Letosteine can be used for acute or chronic respiratory diseases (such as bronchopneumopathies) research[1][2][3]. Properties Name 2-[2-(2-ethoxy-2-oxoethyl)sulfanylethyl]-1,3-thiazolidine-4-carboxylic acid Synonym More Synonyms Letosteine Biological Activity Description Letosteine is an orally active, potent and safe expectorant. Letosteine dissolves bronchial mucus and reduces respiratory inflammation symptoms, and restores gas exchanges and natural defense mechanisms in the lung. Letosteine can be used for acute or chronic respiratory diseases (such as bronchopneumopathies) research[1][2][3]. Related Catalog Research Areas >> Inflammation/Immunology References [1]. [1]Jia L. Letosteine. John Wiley & Sons, Ltd, 2014. [2]. [2] Macquet V, et al. A new contribution to the treatment of chronic bronchopneumopathies: letosteine. Lille Med. 1979;24(9):735-738. [3]. [3] Zhou Y, et al. Efficacy and safety of letosteine in the treatment of sputum thickening and expectoration difficulty in patients with respiratory diseases: a multicenter, randomized, double-masked, double dummy, positive drug parallel controlled trial. Pharmazie. 2014;69(11):842-849. [4]. [4] Gachon F, et al. Disposition and metabolism of letosteine in rats. Drug Metab Dispos. 1988;16(6):853-857. Chemical & Physical Properties Molecular Formula C10H17NO4S2 Exact Mass 279.06000 PSA 126.23000 LogP 1.11730 Index of Refraction 1.547 InChIKey IKOCLISPVJZJEA-UHFFFAOYSA-N SMILES CCOC(=O)CSCCC1NC(C(=O)O)CS1 Safety Information Hazard Codes Xn HS Code 2934999090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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