CAS Number49557-75-7
SynonymsLiver growth factor; Gly-L-His-L-Lys; Liver cell growth factor; Glycyl-L-Histidyl-L-Lysine; GHK Cu Copper Peptide; H-Gly-His-Lys-OH; glycyl-histidyl-lysine; ghk; Copper Peptide; Ahk-cu; Growth-modulating peptide; Gly-His-Lys-Cu; Copper Peptide (GHK-Cu)
Molecular FormulaC14H24O4N6
Molecular Weight340.38
Purity98.00%
Density1.3±0.1 g/cm3
Boiling Point831.0±65.0 °C at 760 mmHg
Appearancewhite powder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 49557-75-7 |
| Catalog No. | 2A-9043172 |
| Chinese Name | 铜肽 |
| Synonyms | Liver growth factor; Gly-L-His-L-Lys; Liver cell growth factor; Glycyl-L-Histidyl-L-Lysine; GHK Cu Copper Peptide; H-Gly-His-Lys-OH; glycyl-histidyl-lysine; ghk; Copper Peptide; Ahk-cu; Growth-modulating peptide; Gly-His-Lys-Cu; Copper Peptide (GHK-Cu) |
| Molecular Formula | C14H24O4N6 |
| Molecular Weight | 340.38 |
| Purity | 98.00 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 831.0±65.0 °C at 760 mmHg |
| Appearance | white powder |
| Storage Condition | 2-8°C |
| Application | Glycyl-L-histidine-L-lysine is a tripeptide consisting of sequentially linked glycine, L-histamine, and L-lysine residues. Glycyl-L-histidine-L-lysine is a liver-stimulating immunosuppressant with anx |
| HTC | 2933290090 |
| PubChem ID | 8195782 |
| MDL Number | MFCD00036754 |
| SMILES | NCCCCC(NC(=O)C(Cc1cnc[nH]1)NC(=O)CN)C(=O)O |
| InChI | InChI=1S/C14H24N6O4/c15-4-2-1-3-10(14(23)24)20-13(22)11(19-12(21)6-16)5-9-7-17-8-18-9/h7-8,10-11H,1-6,15-16H2,(H,17,18)(H,19,21)(H,20,22)(H,23,24)/t10-,11-/m0/s1 |
| InChI Key | MVORZMQFXBLMHM-QWRGUYRKSA-N |
| MSDS | msds/43172_1_49557_75_7.pdf |
| Use of | Glycyl-L-histidyl-L-lysine is a tripeptide consisting of glycine, L-histidine and L-lysine residues joined in sequence. Glycyl-L-histidyl-L-lysine is a hepatotropic immunosuppressor and shows anxiolytic effect. Glycyl-L-histidyl-L-lysine and its copper complexes show good skin tolerance[1][2][3]. Properties Name Gly-His-Lys Synonym More Synonyms Copper Peptide Biological Activity Description Glycyl-L-histidyl-L-lysine is a tripeptide consisting of glycine, L-histidine and L-lysine residues joined in sequence. Glycyl-L-histidyl-L-lysine is a hepatotropic immunosuppressor and shows anxiolytic effect. Glycyl-L-histidyl-L-lysine and its copper complexes show good skin tolerance[1][2][3]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease In Vitro Glycyl-L-histidyl-L-lysine and its copper complexes and saccharomyces/copper ferment on secretion of pro-inflammatory IL-6 in normal human dermal fibroblasts NHDF cell line[1]. Glycyl-L-histidyl-L-lysine and its copper complexes decreases TNF-α-dependent IL-6 secretion in fibroblasts[1]. References [1]. Arkadiusz Gruchlik, et al. Effect of Gly-Gly-His, Gly-His-Lys and their copper complexes on TNF-alpha-dependent IL-6 secretion in normal human dermal fibroblasts. Acta Pol Pharm. 2012 Nov-Dec;69(6):1303-6. [2]. M Yu Smakhtin, et al. Tripeptide Gly-His-Lys is a hepatotropic immunosuppressor. Bull Exp Biol Med. 2002 Jun;133(6):586-7. [3]. I Bobyntsev, et al. Anxiolytic effects of Gly-His-Lys peptide and its analogs. Bull Exp Biol Med. 2015 Apr;158(6):726-8. Chemical & Physical Properties Molecular Formula C14H24N6O4 Exact Mass 340.185913 PSA 176.22000 LogP -2.24 Index of Refraction 1.583 InChIKey MVORZMQFXBLMHM-QWRGUYRKSA-N Safety Information Hazard Codes Xi HS Code 2933290090 Precursor & DownStream Precursor 3 CAS#:29022-11-5 Fmoc-Gly-OH CAS#:71989-26-9 Fmoc-Lys(Boc)-OH CAS#:109425-51-6 Fmoc-His(Trt)-OH DownStream 0 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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