CAS Number40716-66-3
SynonymsEINECS 255-053-4; ±-trans-Nerolidol; (6E)-3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol; Nerolidol trans-form; Peruviol; (6E)-Nerolidol; 10,11-Dihydronerolidol; (E)-3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol,trans-3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol; Nerolidol, trans; trans-1-Cyclohexyl-2,3-dibenzoyl-aziridin; MFCD00008911; Nerolidol; (±)-trans-Nerolidol; 6,7-dihydronerolidol; E-Nerolidol; (±)-Nerolidol; 3,7,11-trimethyldodeca-1,6,10-trien-3-ol; (6E)-3,7,11-trimethyldodeca-1,6,10-trien-3-ol; Trans-nerolidol; trans-N-Cyclohexyl-2,3-dibenzoyl-aziridin
Molecular Formula(CH3)2C=CHCH2CH2C(CH3)=CHCH2CH2C(CH3)(OH)CH=CH2
Molecular Weight222.37
Purity98.00%
Density0.9±0.1 g/cm3
Boiling Point276.0±0.0 °C at 760 mmHg
Appearanceoily object
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 40716-66-3 |
| Catalog No. | 2A-0201324 |
| Chinese Name | 反式-橙花叔醇 |
| Synonyms | EINECS 255-053-4; ±-trans-Nerolidol; (6E)-3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol; Nerolidol trans-form; Peruviol; (6E)-Nerolidol; 10,11-Dihydronerolidol; (E)-3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol,trans-3,7,11-Trimethyl-1,6,10-dodecatrien-3-ol; Nerolidol, trans; trans-1-Cyclohexyl-2,3-dibenzoyl-aziridin; MFCD00008911; Nerolidol; (±)-trans-Nerolidol; 6,7-dihydronerolidol; E-Nerolidol; (±)-Nerolidol; 3,7,11-trimethyldodeca-1,6,10-trien-3-ol; (6E)-3,7,11-trimethyldodeca-1,6,10-trien-3-ol; Trans-nerolidol; trans-N-Cyclohexyl-2,3-dibenzoyl-aziridin |
| Molecular Formula | (CH3)2C=CHCH2CH2C(CH3)=CHCH2CH2C(CH3)(OH)CH=CH2 |
| Molecular Weight | 222.37 |
| Purity | 98.00 |
| Density | 0.9±0.1 g/cm3 |
| Boiling Point | 276.0±0.0 °C at 760 mmHg |
| Appearance | oily object |
| Storage Condition | ?20°C |
| Application | Trans-Nerolidol is a sesquiterpene alcohol. It can be separated from the aerial part of Warionia saharae ex Benth. Trans-Nerolidol improves the antiproliferative effect of doxorubicin (HY-15142A) on i |
| HTC | 2905290000 |
| PubChem ID | 329747955 |
| SMILES | C=CC(C)(O)CCC=C(C)CCC=C(C)C |
| InChI | InChI=1S/C15H26O/c1-6-15(5,16)12-8-11-14(4)10-7-9-13(2)3/h6,9,11,16H,1,7-8,10,12H2,2-5H3/b14-11+ |
| InChI Key | FQTLCLSUCSAZDY-SDNWHVSQSA-N |
| Use of | trans-Nerolidol is a sesquiterpene alcohol. It can be isolated from f aerial parts of Warionia saharae ex Benth. trans-Nerolidol improves the anti-proliferative effect of Doxorubicin (HY-15142A) against intestinal cancer cells in vitro. trans-Nerolidol also has anti-fungal activity[1][2]. Properties Articles30 Name Nerolidol Synonym More Synonyms (±)-trans-Nerolidol Biological Activity Description trans-Nerolidol is a sesquiterpene alcohol. It can be isolated from f aerial parts of Warionia saharae ex Benth. trans-Nerolidol improves the anti-proliferative effect of Doxorubicin (HY-15142A) against intestinal cancer cells in vitro. trans-Nerolidol also has anti-fungal activity[1][2]. Related Catalog Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal References [1]. Hanušová V, et al. The effects of β-caryophyllene oxide and trans-nerolidol on the efficacy of doxorubicin in breast cancer cells and breast tumor-bearing mice. Biomed Pharmacother. 2017 Nov;95:828-836. [2]. Chan WK, et al. Nerolidol: A Sesquiterpene Alcohol with Multi-Faceted Pharmacological and Biological Activities. Molecules. 2016 Apr 28;21(5):529. Chemical & Physical Properties Molecular Formula C15H26O Exact Mass 222.198364 PSA 20.23000 Index of Refraction 1.480 InChIKey FQTLCLSUCSAZDY-SDNWHVSQSA-N SMILES C=CC(C)(O)CCC=C(C)CCC=C(C)C Safety Information Signal Word Warning Hazard Statements H315-H319-H335 Precautionary Statements P261-P305 + P351 + P338 Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter Hazard Codes Xi:Irritant; Safety Phrases S26-S36 RIDADR NONH for all modes of transport WGK Germany 1 HS Code 2905290000 Synthetic Route (2S)-methyl 2-(... 139167-57-0 (±)-tran... 40716-66-3 139167-61-6 (S)-methyl 2-((... 139167-62-7 Literature: Gordon, Eric M.; Pluscec, Jelka Journal of the American Chemical Society, 1992 , vol. 114, # 4 p. 1521 - 1523 Geranylacetone Vinylmagnesium ... (±)-tran... 40716-66-3 Literature: Cane,D.E.; Iyengar,R.; Shiao,M.S. Journal of the American Chemical Society, 1981 , vol. 103, p. 914 3-hydroxy-3,7,1... 59905-15-6 (±)-tran... 40716-66-3 Literature: Nigmatov, A. G.; Serebryakov, E. P.; Yanovskaya, L. A. Pharmaceutical Chemistry Journal, 1987 , vol. 21, # 7 p. 529 - 533 Khimiko-Farmatsevticheskii Zhurnal, 1987 , vol. 21, # 7 p. 854 - 858 Precursor & DownStream Precursor 9 CAS#:139167-57-0 (2S)-methyl 2-(... CAS#:3796-70-1 Geranylacetone CAS#:1826-67-1 Vinylmagnesium ... CAS#:59905-15-6 3-hydroxy-3,7,1... DownStream 8 CAS#:3891-98-3 2,6,10-Trimethy... CAS#:495-62-5 1-Methyl-4-(6-m... CAS#:515-69-5 alpha-Bisabolol CAS#:18794-84-8 (E)-β-Farnesene |
| Tax Rebate | 9.0% |
| Supervision | none |
| Transport Info | Product Name: Summary 2905290000 unsaturated monohydric alcohols. Supervision conditions:None. VAT: 17.0%. Tax rebate rate:9.0%. MFN tariff:5.5%. General tariff:30.0% |
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