CAS Number27314-97-2
Synonyms4-hydroxy-1-oxido-1,2,4-benzotriazin-1-ium-3-imine; 1,2,4-Benzotriazin-3-amine, 1,4-dioxide; 3-Amino-1,2,4-benzotriazine 1,4-Dioxide; 1,4-Dioxido-1,2,4-benzotriazin-3-ylamine; SR 259075; 1,2,4-Benzotriazin-3-amine 1,4-dioxide; 4-Hydroxy-1-oxido-1,2,4-benzotriazin-1-ium-3-imine SR 259075 SR 4233 Tirazone Win 59075; Tirazone; Tirapazamine; 3-Aminobenzo[e][1,2,4]triazine 1,4-dioxide
Molecular FormulaC7H6N4O2
Molecular Weight178.148
Purity98.00%
Density1.7±0.1 g/cm3
Boiling Point493.6±28.0 °C at 760 mmHg
Melting Point220ºC
AppearanceOrange-red crystalline powder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 27314-97-2 |
| Catalog No. | 2A-9040167 |
| Chinese Name | 替拉扎明 |
| Synonyms | 4-hydroxy-1-oxido-1,2,4-benzotriazin-1-ium-3-imine; 1,2,4-Benzotriazin-3-amine, 1,4-dioxide; 3-Amino-1,2,4-benzotriazine 1,4-Dioxide; 1,4-Dioxido-1,2,4-benzotriazin-3-ylamine; SR 259075; 1,2,4-Benzotriazin-3-amine 1,4-dioxide; 4-Hydroxy-1-oxido-1,2,4-benzotriazin-1-ium-3-imine SR 259075 SR 4233 Tirazone Win 59075; Tirazone; Tirapazamine; 3-Aminobenzo[e][1,2,4]triazine 1,4-dioxide |
| Molecular Formula | C7H6N4O2 |
| Molecular Weight | 178.148 |
| Purity | 98.00 |
| Density | 1.7±0.1 g/cm3 |
| Boiling Point | 493.6±28.0 °C at 760 mmHg |
| Melting Point | 220ºC |
| Appearance | Orange-red crystalline powder |
| Storage Condition | 0-10°C; avoid heating |
| Application | Tirapazamine is an anticancer agent that is selectively cytotoxic to hypoxic cells in solid tumors, inducing single- and double-strand breaks in DNA, base damage, and cell death. |
| SMILES | [NH-]C1=N[N+](=O)c2ccccc2N1O |
| InChI | InChI=1S/C7H6N4O2/c8-7-9-11(13)6-4-2-1-3-5(6)10(7)12/h1-4,12H,(H-,8,9,13) |
| InChI Key | InChIKey=AWKHOOPMYMLWDZ-UHFFFAOYSA-N |
| Transport Info | Product Name: Tirapazamine |
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