CAS Number27262-47-1
Synonyms(2S)-1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide; L-(-)-Bupivacaine; 2',6'-Pipecoloxylidide,1-butyl-,L-(-); 1-Butyl-N-(2,6-dimethylphenyl)-piperidine-2-carboxamide; (-)-Bupivacaine; Levobupivacaine; 1-butyl-piperidine-2-carboxylic acid-(2,6-dimethyl-anilide); (S)-(-)-Bupivacaine; (S)-Bupivacaine; (2S)-1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide
Molecular FormulaC18H28N2O
Molecular Weight288.428
Purity98.00%
Density1.0±0.1 g/cm3
Boiling Point423.4±45.0 °C at 760 mmHg
Melting Point254ºC (dec.)(lit.)
Appearancewhite solid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 27262-47-1 |
| Catalog No. | 2A-9040155 |
| Chinese Name | 左布比卡因 |
| Synonyms | (2S)-1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide; L-(-)-Bupivacaine; 2',6'-Pipecoloxylidide,1-butyl-,L-(-); 1-Butyl-N-(2,6-dimethylphenyl)-piperidine-2-carboxamide; (-)-Bupivacaine; Levobupivacaine; 1-butyl-piperidine-2-carboxylic acid-(2,6-dimethyl-anilide); (S)-(-)-Bupivacaine; (S)-Bupivacaine; (2S)-1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide |
| Molecular Formula | C18H28N2O |
| Molecular Weight | 288.428 |
| Purity | 98.00 |
| Density | 1.0±0.1 g/cm3 |
| Boiling Point | 423.4±45.0 °C at 760 mmHg |
| Melting Point | 254ºC (dec.)(lit.) |
| Appearance | white solid |
| Storage Condition | The warehouse is ventilated and dried at low tempe |
| Application | Levobupivacaine ((S)-(-)-bupivacaine) is a long-acting amide local anesthetic. Levobupivacaine exerts its anesthetic and analgesic effects by reversibly blocking neuronal sodium channels. Levobupivaca |
| HTC | 2933399090 |
| SMILES | CCCCN1CCCCC1C(=O)Nc1c(C)cccc1C |
| InChI Key | LEBVLXFERQHONN-INIZCTEOSA-N |
| Use of | Levobupivacaine ((S)-(-)-Bupivacaine) is a long-acting amide local anaesthetic. Levobupivacaine exerts anaesthetic and analgesic effects through reversible blockade of neuronal sodium channel. Levobupivacaine can inhibit impulse transmission and conduction in cardiovascular and other tissues, possessing certain cardiac and CNS toxicity. Levobupivacaine is metabolized by hepatic cytochrome P450 (CYP450) enzymes in vivo. Levobupivacaine can also induce ferroptosis by miR-489-3p/SLC7A11 signaling in gastric cancer[1][2][3]. Properties Biological Activity Chemical & Physical Properties Toxicological Info Safety Info |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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