CAS Number26988-72-7
Synonyms1-MT; EINECS 248-157-6; MFCD00005803; 2-amino-3-(1-methylindol-3-yl)propanoic acid; 2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid
Molecular FormulaC12H14N2O2
Molecular Weight218.25200
Purity98.00%
Density1.28g/cm3
Boiling Point429.3ºC at 760mmHg
Melting Point250ºC (dec.)(lit.)
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 26988-72-7 |
| Catalog No. | 2A-9040091 |
| Chinese Name | 1-甲基-色氨酸 |
| Synonyms | 1-MT; EINECS 248-157-6; MFCD00005803; 2-amino-3-(1-methylindol-3-yl)propanoic acid; 2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid |
| Molecular Formula | C12H14N2O2 |
| Molecular Weight | 218.25200 |
| Purity | 98.00 |
| Density | 1.28g/cm3 |
| Boiling Point | 429.3ºC at 760mmHg |
| Melting Point | 250ºC (dec.)(lit.) |
| Storage Condition | Sealed in a cool, dry environment |
| Application | (Rac)-Indoximod (1-Methyl-DL-tryptophan) is an indoleamine-2,3-dioxygenase (IDO) inhibitor. The combination of (Rac)-Indoximod and IFN-γ significantly reduced the activity of human cardiac fibroblasts |
| HTC | 2933990090 |
| SMILES | Cn1cc(CC(N)C(=O)O)c2ccccc21 |
| InChI | InChI=1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16) |
| InChI Key | ZADWXFSZEAPBJS-UHFFFAOYSA-N |
| Hazard Symbols | transportation |
| MSDS | msds/40091_2_26988_72_7.pdf |
| Bioactivity | Chemical & Physical Properties |
| Use of | (Rac)-Indoximod (1-Methyl-DL-tryptophan) is an indoleamine 2,3-dioxygenase (IDO) inhibitor. Co-treatment with IFN-γ and (Rac)-Indoximod markedly reduces the activity of human cardiac myofibroblasts (hCMs) expressing α-SMA and induces apoptosis through up-regulating the IRF-1, Fas, and FasL genes[1]. Properties Articles17 Biological Activity Chemical & Physical Properties |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 97.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: No dangerous goods IMDG Code: No dangerous goods International Air Transport Dangerous Regulations: No dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special precautions for users No data available |
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