CAS Number26833-87-4
SynonymsOmacetaxine mepesuccinate; MFCD03410264; Homoharringtonine; Myelostat; O-[(2R)-2,6-Dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine; (-)-homoharringtonine; HOMOHARRINGTONINUM; homoharrigtonine; Synribo; HMoharringtonine; Ceflatonin; Homobarringtonie; HHT; HOMOHARRINGTONIN; CGX 635
Molecular FormulaC29H39NO9
Molecular Weight545.621
Purity98.00%
Density1.3±0.1 g/cm3
Boiling Point713.1±60.0 °C at 760 mmHg
Melting Point144-146ºC
Appearanceoff-white crystal
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 26833-87-4 |
| Catalog No. | 2A-9040051 |
| Chinese Name | 高三尖杉酯碱 |
| Synonyms | Omacetaxine mepesuccinate; MFCD03410264; Homoharringtonine; Myelostat; O-[(2R)-2,6-Dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine; (-)-homoharringtonine; HOMOHARRINGTONINUM; homoharrigtonine; Synribo; HMoharringtonine; Ceflatonin; Homobarringtonie; HHT; HOMOHARRINGTONIN; CGX 635 |
| Molecular Formula | C29H39NO9 |
| Molecular Weight | 545.621 |
| Purity | 98.00 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 713.1±60.0 °C at 760 mmHg |
| Melting Point | 144-146ºC |
| Appearance | off-white crystal |
| Water Solubility | DMSO: soluble20mg/mL, clear |
| Storage Condition | 2-8℃ |
| Packaging | II |
| Application | Homoharringtonine (Omacetaxine mepesuccinate; HHT) is a cytotoxic alkaloid with antitumor properties that acts by inhibiting translation elongation. |
| SMILES | COC(=O)CC(O)(CCCC(C)(C)O)C(=O)OC1C(OC)=CC23CCCN2CCc2cc4c(cc2C13)OCO4 |
| InChI | InChI=1S/C29H39NO9/c1-27(2,33)8-5-10-29(34,16-23(31)36-4)26(32)39-25-22(35-3)15-28-9-6-11-30(28)12-7-18-13-20-21(38-17-37-20)14-19(18)24(25)28/h13-15,24-25,33-34H,5-12,16-17H2,1-4H3/t24-,25+,28-,29?/m0/s1 |
| InChI Key | HYFHYPWGAURHIV-JFIAXGOJSA-N |
| Hazard Symbols | 6.1(a) |
| Bioactivity | Chemical & Physical Properties |
| Use of | Homoharringtonine (Omacetaxine mepesuccinate;HHT) is a cytotoxic alkaloid with antitumor properties which acts by inhibiting translation elongation. Properties Biological Activity Chemical & Physical Properties |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Danger Regulations: 1544 International Maritime Transport Danger Regulations: 1544 International Air Transport Danger Regulations: 1544 14.2 United Nations shipping name European Land Transport Dangerous Regulations: ALKALOIDS, SOLID, N.O.S. (Homoharringtonine) IMDG Code: ALKALOIDS, SOLID, N.O.S. (Homoharringtonine) IMDG Code: Alkaloids, solid, n.o.s. (Homoharringtonine) 14.3 Transport hazard categories European Land Transport Danger Regulations: 6.1 International Maritime Transport Danger Regulations: 6.1 International Air Transport Danger Regulations: 6.1 14.4 Package group European Dangerous Regulations for land transport: II International Dangerous Regulations for sea transport: II International Dangerous Regulations for air transport: II 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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