Home > Products > Specialty & Industrial Chemicals > Specialty Chemicals > 1,2:5,6-Dianhydrogalactitol

1,2:5,6-Dianhydrogalactitol

Name: 1,2:5,6-Dianhydrogalactitol
Brand: 2A Biotech
SKU: 2A-9039225

CAS Number23261-20-3

SynonymsGalactitol,1,2:5,6-dianhydro; 1,2:5,6-Diepoxydulcitol; Dulcitoldiepoxide; 5,6-Diepoxydulcitol; Dianhydrogalactitol; 1,2,5,6-dianhydro-galactitol; 1,2-5,6-dianhydro-dulcitol; Dianhydrodulcitol; VAL-083

Molecular FormulaC6H10O4

Molecular Weight146.14

Purity≥95 (HPLC)%

Density1.567

Boiling Point348ºC at 760mmHg

Appearancepowder

MSDSChinese English

Cat. No.: 2A-9039225 Purity: ≥95 (HPLC)%

Change View

Please Login or Create an Account to: See VlP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

Quality Control of [ 23261-20-3 ] Purity: ≥95 (HPLC)% SDS Specification MoL

Chemical & Physical Properties
CAS Number	23261-20-3
Catalog No.	2A-9039225
Chinese Name	1,2:5,6-二脱水半乳糖醇
Synonyms	Galactitol,1,2:5,6-dianhydro; 1,2:5,6-Diepoxydulcitol; Dulcitoldiepoxide; 5,6-Diepoxydulcitol; Dianhydrogalactitol; 1,2,5,6-dianhydro-galactitol; 1,2-5,6-dianhydro-dulcitol; Dianhydrodulcitol; VAL-083
Molecular Formula	C6H10O4
Molecular Weight	146.14
Purity	≥95 (HPLC)
Density	1.567
Boiling Point	348ºC at 760mmHg
Appearance	powder
Storage Condition	2-8℃
Application	VAL-083 is an alkylating agent that can produce N7 methylation on DNA and has anti-tumor activity.
HTC	2910900090
MDL Number	MFCD01725532
SMILES	O[C@H]([C@@]1(CO1)[H])[C@H]([C@]2(CO2)[H])O
InChI	1S/C6H10O4/c7-5(3-1-9-3)6(8)4-2-10-4/h3-8H,1-2H2/t3-,4+,5+,6-
InChI Key	AAFJXZWCNVJTMK-GUCUJZIJSA-N
UNSPSC	12352200
MSDS	msds/39225_1_23261_20_3.pdf
Use of	Properties Name 1,2-bis(oxiran-2-yl)ethane-1,2-diol Synonym More Synonyms VAL-083 Biological Activity Related Catalog Signaling Pathways >> Cell Cycle/DNA Damage >> DNA Alkylator/Crosslinker Research Areas >> Cancer DNA Alkylator[1] References [1]. Kaiji Hu, et al. Abstract 811: VAL083, a novel N7 alkylating agent, surpasses temozolomide activity and inhibits cancer stem cells providing a new potential treatment option for glioblastoma multiforme. Cancer Research. 2012 Mar 31-Apr 4. [2]. Jiang X, et al. Dianhydrogalactitol, a potential multitarget agent, inhibits glioblastoma migration, invasion, and angiogenesis. Biomed Pharmacother. 2017 Jul;91:1065-1074. Chemical & Physical Properties Molecular Formula C6H10O4 Exact Mass 146.05800 PSA 65.52000 InChIKey AAFJXZWCNVJTMK-GUCUJZIJSA-N Storage condition 2-8℃ Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CAS REGISTRY NUMBER : 23261-20-3 LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : MOLECULAR WEIGHT : WISWESSER LINE NOTATION : T3OTJ BYQYQ- BT3OTJ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Gastrointestinal - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Gastrointestinal - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Gastrointestinal - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 7899 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Gastrointestinal - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 16500 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Gastrointestinal - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : TOXIC EFFECTS : Blood - agranulocytosis Blood - changes in bone marrow (not otherwise specified) Related to Chronic Data - death TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Primate - monkey DOSE/DURATION : TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Nutritional and Gross Metabolic - weight loss or decreased weight gain TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 87500 ug/kg/70D-I TOXIC EFFECTS : Blood - changes in bone marrow (not otherwise specified) TYPE OF TEST : DNA adduct TYPE OF TEST : Mutation test systems - not otherwise specified TYPE OF TEST : DNA inhibition MUTATION DATA TYPE OF TEST : DNA inhibition TEST SYSTEM : Rodent - rabbit Bone marrow DOSE/DURATION : 136 umol/L REFERENCE : BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 25,1705,1976 Safety Information HS Code 2910900090 Precursor & DownStream Precursor 0 DownStream 3 CAS#:23261-25-8 Galactitol,1,6-... CAS#:608-66-2 CAS#:51607-75-1 1,5-anhydro-DL-...
Tax Rebate	13.0%
Supervision	None. MFN tariff: 5.5%. Ordinary tariff: 30.0%
Transport Info	Product name: Summary 2910900090. epoxides, epoxyalcohols, epoxyphenols and epoxyethers, with a three-membered ring, and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Related Products in Specialty Chemicals
L-Propargylglycine	23235-01-0	2A-9039213
D-Propargylglycine	23235-03-2	2A-9039214
Cefacetrile sodium	23239-41-0	2A-9039217
1-Hydroxy-3,4,5-trimethoxyxanthone	23251-63-0	2A-9039222
Bendazac sodium salt	23255-99-4	2A-9039223
Methyl 2-hydroxy-3-methylbenzoate	23287-26-5	2A-9039229
Histamine diphosphate	23297-93-0	2A-9039232
4-(1H-Pyrrol-1-yl)phenol	23351-09-9	2A-9039238
Disperse Brown 1	23355-64-8	2A-9039239
trans-4-Acetamidocyclohexanol	23363-88-4	2A-9039245
Browse all Specialty Chemicals products »

1,2:5,6-Dianhydrogalactitol

Inquiry Form