CAS Number38231-86-6
Synonyms(1S,2S,3R,6S)-6-amino-4-(hydroxymethyl)cyclohex-4-ene-1,2,3-triol; Valienamine; (1S,2S,3R,6S)-6-Amino-4-(hydroxymethyl)-4-cyclohexene-1,2,3-triol; MFCD07357238
Molecular FormulaC7H13NO4
Molecular Weight175.182
Purity98%
Density1.5±0.1 g/cm3
Boiling Point377.3±42.0 °C at 760 mmHg
AppearanceSlightly yellow solid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 38231-86-6 |
| Catalog No. | 2A-9000039 |
| Chinese Name | 井冈霉烯胺盐酸盐 |
| Synonyms | (1S,2S,3R,6S)-6-amino-4-(hydroxymethyl)cyclohex-4-ene-1,2,3-triol; Valienamine; (1S,2S,3R,6S)-6-Amino-4-(hydroxymethyl)-4-cyclohexene-1,2,3-triol; MFCD07357238 |
| Molecular Formula | C7H13NO4 |
| Molecular Weight | 175.182 |
| Purity | 98 |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 377.3±42.0 °C at 760 mmHg |
| Appearance | Slightly yellow solid |
| Storage Condition | Hygroscopic, Store under Inert atmosphere Refriger |
| Application | Valine amine is an alpha-glucosidase inhibitor. Valine is a key functional ingredient in many natural glycosidase inhibitors, including the crop protectant valamycin A and the anti-diabetic agent acar |
| HTC | 2922199090 |
| SMILES | NC1C=C(CO)C(O)C(O)C1O |
| InChI | InChI=1S/C7H13NO4/c8-4-1-3(2-9)5(10)7(12)6(4)11/h1,4-7,9-12H,2,8H2/t4-,5+,6-,7-/m0/s1 |
| InChI Key | XPHOBMULWMGEBA-VZFHVOOUSA-N |
| Use of | Valienamine is the alpha-glucosidase inhibitor. Valienamine is the key functional component of many natural glycosidase inhibitors including the crop protectant validamycin A and the antidiabetic agent acarbose[1]. Properties Name (+)-Valienamine Hydrochloride Synonym More Synonyms Valienamine Biological Activity Description Valienamine is the alpha-glucosidase inhibitor. Valienamine is the key functional component of many natural glycosidase inhibitors including the crop protectant validamycin A and the antidiabetic agent acarbose[1]. Related Catalog Research Areas >> Metabolic Disease alpha-glucosidase[1] References [1]. Degwert U, et al. Studies on the biosynthesis of the alpha-glucosidase inhibitor acarbose: valienamine, a m-C7N unit not derived from the shikimate pathway. J Antibiot (Tokyo). 1987;40(6):855-861. [2]. Cui L, et al. A Validamycin Shunt Pathway for Valienamine Synthesis in Engineered Streptomyces hygroscopicus 5008. ACS Synth Biol. 2020;9(2):294-303. Chemical & Physical Properties Molecular Formula C7H13NO4 Exact Mass 175.084457 PSA 106.94000 LogP -1.60 Index of Refraction 1.649 InChIKey XPHOBMULWMGEBA-VZFHVOOUSA-N Storage condition Hygroscopic, Store under Inert atmosphere Refrigerator Safety Information Hazard Codes Xi HS Code 2922199090 Synthetic Route 227930-76-9 Valienamine 38231-86-6 Literature: Kapferer, Peter; Sarabia, Francisco; Vasella, Andrea Helvetica Chimica Acta, 1999 , vol. 82, # 5 p. 645 - 656 1,1'-bis-va... 148291-19-4 Valienamine 38231-86-6 Literature: State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University Patent: US8101732 B2, 2012 ; Location in patent: Page/Page column 28 ; 4-(Hydroxymethy... 38665-10-0 validamine 32780-32-8 Valienamine 38231-86-6 Literature: State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University Patent: US8101732 B2, 2012 ; Location in patent: Page/Page column 28 ; Precursor & DownStream Precursor 7 CAS#:227930-76-9 CAS#:38665-10-0 4-(Hydroxymethy... CAS#:114779-32-7 CAS#:107960-21-4 ((3S,4S,5S,6R)-... DownStream 4 CAS#:32780-32-8 validamine CAS#:38231-87-7 CAS#:83465-22-9 Valiolamine CAS#:85281-06-7 6,7,8-TRIHYDROX... |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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