CAS Number22224-41-5
Synonymsα-D-Ribofuranose, 1,3,5-tribenzoate; 1,3,5-Tri-O-benzoyl-a-D-ribofuranose; MFCD00080818; 1,3,5-Tri-O-benzoyl-α-d-ribofuranose; a-D-Ribofuranose,1,3,5-tribenzoate; 1,3,5-TRIBENZOYL-A-D-RIBOFURANOSE; 1,3,5-tribenzoate-a-D-Ribofuranose
Molecular FormulaC26H22O8
Molecular Weight462.45
Purity98.00%
Density1.4±0.1 g/cm3
Boiling Point629.6±55.0 °C at 760 mmHg
Melting Point125-129 °C(lit.)
AppearanceWhite to off-white powder or fibrous powder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 22224-41-5 |
| Catalog No. | 2A-9038913 |
| Chinese Name | 1,3,5-三苯甲酰基-D-呋喃核糖 |
| Synonyms | α-D-Ribofuranose, 1,3,5-tribenzoate; 1,3,5-Tri-O-benzoyl-a-D-ribofuranose; MFCD00080818; 1,3,5-Tri-O-benzoyl-α-d-ribofuranose; a-D-Ribofuranose,1,3,5-tribenzoate; 1,3,5-TRIBENZOYL-A-D-RIBOFURANOSE; 1,3,5-tribenzoate-a-D-Ribofuranose |
| Molecular Formula | C26H22O8 |
| Molecular Weight | 462.45 |
| Purity | 98.00 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 629.6±55.0 °C at 760 mmHg |
| Melting Point | 125-129 °C(lit.) |
| Appearance | White to off-white powder or fibrous powder |
| Storage Condition | Closed, cool, ventilated and dry place |
| Application | 1,3,5-Tris-O-benzoyl-a-D-ribofuranose is a purine nucleoside analog. Purine nucleoside analogues have broad antitumor activity and target indolent lymphoid malignancies. The anti-cancer mechanism in t |
| SMILES | O=C(OCC1OC(OC(=O)c2ccccc2)C(O)C1OC(=O)c1ccccc1)c1ccccc1 |
| InChI Key | HUHVPBKTTFVAQF-PIXQIBFHSA-N |
| MSDS | msds/38913_1_22224_41_5.pdf |
| Bioactivity | 1,3,5-Tri-O-benzoyl-a-D-ribofuranose is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog References [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. Chemical & Physical Properties Density 1.4±0.1 g/cm3 Boiling Point 629.6±55.0 °C at 760 mmHg Melting Point 125-129 °C(lit.) Molecular Formula C26H22O8 Molecular Weight 462.45 Flash Point 213.0±25.0 °C Exact Mass 462.131470 PSA 108.36000 LogP 6.12 Vapour Pressure 0.0±1.9 mmHg at 25°C Index of Refraction 1.633 InChIKey HUHVPBKTTFVAQF-PIXQIBFHSA-N SMILES O=C(OCC1OC(OC(=O)c2ccccc2)C(O)C1OC(=O)c1ccccc1)c1ccccc1 Storage condition 2~8 ℃ |
| Use of | 1,3,5-Tri-O-benzoyl-a-D-ribofuranose is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Properties Name 1,3,5-Tri-O-benzoyl-D-ribofuranose Synonym More Synonyms 1,3,5-Tri-O-benzoyl-α-D-ribofuranose Biological Activity Description 1,3,5-Tri-O-benzoyl-a-D-ribofuranose is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog References [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. Chemical & Physical Properties Molecular Formula C26H22O8 Exact Mass 462.131470 PSA 108.36000 Index of Refraction 1.633 InChIKey HUHVPBKTTFVAQF-PIXQIBFHSA-N Storage condition 2~8 ℃ |
| Transport Info | Product name: 1,3,5-Tri-O-benzoyl-α-D-ribofuranose |
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