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6-Biopterin

Name: 6-Biopterin
Brand: 2A Biotech
SKU: 2A-9038895

CAS Number22150-76-1

SynonymsD-erythro-Biopterin; 2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-4(1H)-pteridinone; 2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]pteridin-4(8H)-one; biopterin; MFCD00036787; L-Biopterin; Pterin HB2; pterinhb2; (-)-Biopterin; L-Erythro-Biopterin; 6-BIOPTERIN; EINECS 244-807-8; (1R,2S)-1-(4-Hydroxy-2-imino-1,2-dihydro-6-pteridinyl)-1,2-propanediol; [S-(R*,S*)]-2-Amino-6-(1,2-dihydroxypropyl)-4(1H)-pteridinone; (1'S,2'R)-Biopterin; Pterin H B2

Molecular FormulaC9H11N5O3

Molecular Weight237.22

Purity≥97%

Density1.9±0.1 g/cm3

Boiling Point563.4±60.0 °C at 760 mmHg

Melting Point>210°C dec.

Appearancepowder

EINECS244-807-8

MSDSChinese English

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Cat. No.: 2A-9038895 Purity: ≥97%

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Quality Control of [ 22150-76-1 ] Purity: ≥97% SDS Specification MoL

Chemical & Physical Properties
CAS Number	22150-76-1
Catalog No.	2A-9038895
Chinese Name	L-生物喋呤
Synonyms	D-erythro-Biopterin; 2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-4(1H)-pteridinone; 2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]pteridin-4(8H)-one; biopterin; MFCD00036787; L-Biopterin; Pterin HB2; pterinhb2; (-)-Biopterin; L-Erythro-Biopterin; 6-BIOPTERIN; EINECS 244-807-8; (1R,2S)-1-(4-Hydroxy-2-imino-1,2-dihydro-6-pteridinyl)-1,2-propanediol; [S-(R,S)]-2-Amino-6-(1,2-dihydroxypropyl)-4(1H)-pteridinone; (1'S,2'R)-Biopterin; Pterin H B2
Molecular Formula	C9H11N5O3
Molecular Weight	237.22
Purity	≥97
Density	1.9±0.1 g/cm3
Boiling Point	563.4±60.0 °C at 760 mmHg
Melting Point	>210°C dec.
Appearance	powder
Storage Condition	This product should be sealed and stored in a dry
Application	6-Biopterin (L-Biopterin), a pterin derivative, is a cofactor of nitric oxide synthase (NO synthase).
EINECS	244-807-8
HTC	2933990090
PubChem ID	24891654
MDL Number	MFCD00036787
SMILES	C[C@H](O)[C@H](O)c1cnc2NC(N)=NC(=O)c2n1
InChI	1S/C9H11N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h2-3,6,15-16H,1H3,(H3,10,11,13,14,17)/t3-,6-/m0/s1
InChI Key	LHQIJBMDNUYRAM-DZSWIPIPSA-N
Beilstein/REAXYS	87860
NACRES Code	NA.51
UNSPSC	41106305
Hazard Symbols	transportation
MSDS	msds/38895_1_22150_76_1.pdf
Bioactivity	6-Biopterin (L-Biopterin), a pterin derivative, is a NO synthase cofactor. Related Catalog Signaling Pathways >> Immunology/Inflammation >> NO Synthase Natural Products >> Saccharides and Glycosides Research Areas >> Cancer Research Areas >> Neurological Disease Target Human Endogenous Metabolite In Vitro 6-biopterin is extremely cytotoxic to human melanocytes under in vitro conditions. Thioredoxin reductase has the capacity to reduce 6-biopterin to q-BH2 where further reduction to 6-BH4 follows via dihydropteridine reductase or reduced glutathione. (6R)5,6,7,8 tetrahydrobiopterin undergoes redox-cycling by its oxidation to quinonoid dihydrobiopterin and to 6-biopterin through consecutive two electron oxidation reactions[1]. References [1]. Schallreuter KU, et al. Cytotoxicity of 6-biopterin to human melanocytes. Biochem Biophys Res Commun. 1994 Oct 14;204(1):43-8. Chemical & Physical Properties Density 1.9±0.1 g/cm3 Boiling Point 563.4±60.0 °C at 760 mmHg Melting Point >210°C dec. Molecular Formula C9H11N5O3 Molecular Weight 237.215 Flash Point 294.5±32.9 °C Exact Mass 237.086182 PSA 138.01000 LogP -3.84 Vapour Pressure 0.0±1.6 mmHg at 25°C Index of Refraction 1.822
Use of	6-Biopterin (L-Biopterin), a pterin derivative, is a NO synthase cofactor. Properties Articles52 Name biopterin Synonym More Synonyms 6-Biopterin Biological Activity Description 6-Biopterin (L-Biopterin), a pterin derivative, is a NO synthase cofactor. Related Catalog Signaling Pathways >> Immunology/Inflammation >> NO Synthase Natural Products >> Saccharides and Glycosides Research Areas >> Cancer Research Areas >> Neurological Disease Human Endogenous Metabolite In Vitro 6-biopterin is extremely cytotoxic to human melanocytes under in vitro conditions. Thioredoxin reductase has the capacity to reduce 6-biopterin to q-BH2 where further reduction to 6-BH4 follows via dihydropteridine reductase or reduced glutathione. (6R)5,6,7,8 tetrahydrobiopterin undergoes redox-cycling by its oxidation to quinonoid dihydrobiopterin and to 6-biopterin through consecutive two electron oxidation reactions[1]. References [1]. Schallreuter KU, et al. Cytotoxicity of 6-biopterin to human melanocytes. Biochem Biophys Res Commun. 1994 Oct 14;204(1):43-8. Chemical & Physical Properties Molecular Formula C9H11N5O3 Exact Mass 237.086182 PSA 138.01000 LogP -3.84 Index of Refraction 1.822
Tax Rebate	13.0%
Supervision	None. MFN tariff: 6.5%. Ordinary tariff: 20.0%
Transport Info	Product name: Purity: 97.0%
MSDS Transport Info	Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available

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6-Biopterin

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