CAS Number21668-77-9
Synonymspropanedisulfonate; Propane-1,3-disulfonate; Eprodisate [INN]; eprodisate; 1.3-propanesultone; 1,3-propane sulfone; Propane-1,3-disulfonic acid; 1,3-propanedisulphonic acid; 1,3-Propanedisulfonic acid; 1,3-Propanedisulfonicacid; UNII-6QFP76V7S7; P8454_ALDRICH; 1,3-Propane disulfonate; MFCD00191483
Molecular FormulaC3H6O6S2Na2
Molecular Weight248.19
Purity98.00%
Density1.8±0.1 g/cm3
Melting Point120-124ºC
AppearanceLiquid;Colorless to Light yellow clear liquid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 21668-77-9 |
| Catalog No. | 2A-9038749 |
| Chinese Name | 1,3-丙二磺酸 |
| Synonyms | propanedisulfonate; Propane-1,3-disulfonate; Eprodisate [INN]; eprodisate; 1.3-propanesultone; 1,3-propane sulfone; Propane-1,3-disulfonic acid; 1,3-propanedisulphonic acid; 1,3-Propanedisulfonic acid; 1,3-Propanedisulfonicacid; UNII-6QFP76V7S7; P8454_ALDRICH; 1,3-Propane disulfonate; MFCD00191483 |
| Molecular Formula | C3H6O6S2Na2 |
| Molecular Weight | 248.19 |
| Purity | 98.00 |
| Density | 1.8±0.1 g/cm3 |
| Melting Point | 120-124ºC |
| Appearance | Liquid;Colorless to Light yellow clear liquid |
| Storage Condition | Keep receptacles sealed Place in a tight container |
| Packaging | III |
| Application | Eprodisate is a new compound designed to interfere with the interaction between amyloidogenic proteins and glycosaminoglycans, thereby inhibiting the polymerization of amyloid fibrils and the depositi |
| HTC | 2904100000 |
| MDL Number | MFCD00191483 |
| SMILES | O=S(=O)(O)CCCS(=O)(=O)O |
| InChI | InChI=1S/C3H8O6S2/c4-10(5,6)2-1-3-11(7,8)9/h1-3H2,(H,4,5,6)(H,7,8,9)/p-2 |
| InChI Key | MGNVWUDMMXZUDI-UHFFFAOYSA-N |
| Hazard Symbols | 8 |
| MSDS | msds/38749_1_21668_77_9.pdf |
| Bioactivity | Eprodisate is a new compound designed to interfere with interactions between amyloidogenic proteins and glycosaminoglycans and thereby inhibit polymerization of amyloid fibrils and deposition of the fibrils in tissues[1]. Eprodisate slow the progression of AA amyloidosis-related renal disease and has possible applicability to other types of amyloidosis[2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology References [1]. Dember LM, et al. Eprodisate for the treatment of renal disease in AA amyloidosis. N Engl J Med. 2007 Jun 7;356(23):2349-60. [2]. Manenti L, et al. Eprodisate in amyloid A amyloidosis: a novel therapeutic approach? Expert Opin Pharmacother. 2008 Aug;9(12):2175-80. Chemical & Physical Properties Density 1.8±0.1 g/cm3 Melting Point 120-124ºC Molecular Formula C3H8O6S2 Molecular Weight 204.222 Exact Mass 203.976227 PSA 125.50000 LogP -3.47 Index of Refraction 1.549 InChIKey MGNVWUDMMXZUDI-UHFFFAOYSA-N SMILES O=S(=O)(O)CCCS(=O)(=O)O |
| Use of | Eprodisate is a new compound designed to interfere with interactions between amyloidogenic proteins and glycosaminoglycans and thereby inhibit polymerization of amyloid fibrils and deposition of the fibrils in tissues[1]. Eprodisate slow the progression of AA amyloidosis-related renal disease and has possible applicability to other types of amyloidosis[2]. Properties Name propane-1,3-disulfonic acid Synonym More Synonyms eprodisate Biological Activity Description Eprodisate is a new compound designed to interfere with interactions between amyloidogenic proteins and glycosaminoglycans and thereby inhibit polymerization of amyloid fibrils and deposition of the fibrils in tissues[1]. Eprodisate slow the progression of AA amyloidosis-related renal disease and has possible applicability to other types of amyloidosis[2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology References [1]. Dember LM, et al. Eprodisate for the treatment of renal disease in AA amyloidosis. N Engl J Med. 2007 Jun 7;356(23):2349-60. [2]. Manenti L, et al. Eprodisate in amyloid A amyloidosis: a novel therapeutic approach? Expert Opin Pharmacother. 2008 Aug;9(12):2175-80. Chemical & Physical Properties Molecular Formula C3H8O6S2 Exact Mass 203.976227 PSA 125.50000 LogP -3.47 Index of Refraction 1.549 InChIKey MGNVWUDMMXZUDI-UHFFFAOYSA-N SMILES O=S(=O)(O)CCCS(=O)(=O)O |
| Tax Rebate | 9.0% |
| Supervision | none |
| Transport Info | Product name: Purity: 70.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Danger Regulations: 1760 International Maritime Transport Danger Regulations: 1760 International Air Transport Danger Regulations: 1760 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: CORROSIVE LIQUID, N.O.S. (1,3-propanedisulfonic acid) IMDG Code: CORROSIVE LIQUID, N.O.S. (1,3-propanedisulfonic acid) International air transport hazard regulations: Corrosive liquid, n.o.s. (1,3-propanedisulfonic acid) 14.3 Transport hazard categories European Dangerous Regulations for land transport: 8 International Dangerous Regulations for sea transport: 8 International Dangerous Regulations for air transport: 8 14.4 Package group European Dangerous Regulations for land transport: II International Dangerous Regulations for sea transport: II International Dangerous Regulations for air transport: II 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| 1H,1H,2H-Perfluoro-1-decene | 21652-58-4 | 2A-9038741 |
| Rhodium trihydroxide | 21656-02-0 | 2A-9038743 |
| 3-Methoxybenzoylacetonitrile | 21667-60-7 | 2A-9038746 |
| 3-Fluorobenzoylacetonitrile | 21667-61-8 | 2A-9038747 |
| 3-Cyanobenzoylacetonitrile | 21667-63-0 | 2A-9038748 |
| 3-S-Isothiuronium propyl sulfonate | 21668-81-5 | 2A-9038750 |
| N-[4-(2-Bromoacetyl)phenyl)acetamide | 21675-02-5 | 2A-9038752 |
| 3-(N-Cyanoethyl)aminoacetanilide | 21678-63-7 | 2A-9038753 |
| N-(3-(Bis(2-cyanoethyl)amino)phenyl)acetamide | 21678-64-8 | 2A-9038754 |
| Ethyl 6-methylnicotinate | 21684-59-3 | 2A-9038758 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS