CAS Number20187-55-7
Synonymsbendazolic acid; Bendazacum; Bendazaco; [(1-Benzyl-1H-indazol-3-yl)oxy]acetic acid; Zildasac; (1-Benzyl-1H-indazol-3-yloxy)-acetic acid; 1-Benzylindazole-3-oxyacetic acid; Versus; Bendazacum [INN-Latin]; [(1-Benzyl-3-indazolyl)oxy]acetic Acid; Bendazac; EINECS 243-569-2; MFCD00866158; Bindazac; [[1-(Phenylmethyl)-1H-indazol-3-yl]oxy]acetic Acid; 2-(1-benzylindazol-3-yl)oxyacetic acid; 2-((1-Benzyl-1H-indazol-3-yl)oxy)acetic acid
Molecular FormulaC16H14N2O3
Molecular Weight282.29
Purity≥98 (HPLC)%
Density1.3±0.1 g/cm3
Boiling Point508.2±35.0 °C at 760 mmHg
Melting Point161-163ºC
Appearancepowder
EINECS243-569-2
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 20187-55-7 |
| Catalog No. | 2A-9038328 |
| Chinese Name | 苄达酸 |
| Synonyms | bendazolic acid; Bendazacum; Bendazaco; [(1-Benzyl-1H-indazol-3-yl)oxy]acetic acid; Zildasac; (1-Benzyl-1H-indazol-3-yloxy)-acetic acid; 1-Benzylindazole-3-oxyacetic acid; Versus; Bendazacum [INN-Latin]; [(1-Benzyl-3-indazolyl)oxy]acetic Acid; Bendazac; EINECS 243-569-2; MFCD00866158; Bindazac; [[1-(Phenylmethyl)-1H-indazol-3-yl]oxy]acetic Acid; 2-(1-benzylindazol-3-yl)oxyacetic acid; 2-((1-Benzyl-1H-indazol-3-yl)oxy)acetic acid |
| Molecular Formula | C16H14N2O3 |
| Molecular Weight | 282.29 |
| Purity | ≥98 (HPLC) |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 508.2±35.0 °C at 760 mmHg |
| Melting Point | 161-163ºC |
| Appearance | powder |
| Water Solubility | Water solubility: insoluble; soluble in: acetone, |
| Storage Condition | Ventilated and low temperature drying |
| Application | Bendazac is an oxyacetic acid with anti-inflammatory, anti-allergic, choleretic and anti-lipidemic properties. Bendazac prevents protein denaturation and delays the development of cataracts. |
| EINECS | 243-569-2 |
| HTC | 2933990090 |
| PubChem ID | 329825514 |
| MDL Number | MFCD00866158 |
| SMILES | OC(COC1=NN(CC2=CC=CC=C2)C3=CC=CC=C31)=O |
| InChI | 1S/C16H14N2O3/c19-15(20)11-21-16-13-8-4-5-9-14(13)18(17-16)10-12-6-2-1-3-7-12/h1-9H,10-11H2,(H,19,20) |
| InChI Key | BYFMCKSPFYVMOU-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| MSDS | msds/38328_1_20187_55_7.pdf |
| Bioactivity | Bendazac is an oxyacetic acid with anti-inflammatory, antinecrotic, choleretic and antilipidaemic properties. Bendazac acts by preventing protein denaturation and delays the cataractogenic process[1][2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology In Vitro Bendazac is an anti-inflammatory agent endowed with protein antidenaturant properties effective for various inflammatory skin conditions. Bendazac has been shown to be a strong reacting substrate in a chemical oxidizing system, which mimics a physiological pathway of hydroxy radical generation[2]. By using EPR spectroscopy of spin-labelled bovine serum albumin (BSA), Bendazac was shown to prevent the BSA denaturation induced by urea, heat and free radicals produced in the xanthine/xanthine oxidase system[2]. References [1]. Balfour JA, et al. Bendazac lysine. A review of its pharmacological properties and therapeutic potential in the management of cataracts. Drugs. 1990;39(4):575-596. [2]. Guglielmotti A, et al. Radical scavenger activity of bendazac, an anticataract non-steroidal anti-inflammatory agent. Pharmacol Res. 1995;32(6):369-373. [3]. Musci G, et al. Mechanism of the scavenger-like activity of bendazac. Drugs Exp Clin Res. 1987;13(5):289-292. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 508.2±35.0 °C at 760 mmHg Melting Point 161-163ºC Molecular Formula C16H14N2O3 Molecular Weight 282.294 Flash Point 261.1±25.9 °C Exact Mass 282.100433 PSA 64.35000 LogP 3.06 Vapour Pressure 0.0±1.4 mmHg at 25°C Index of Refraction 1.630 InChIKey BYFMCKSPFYVMOU-UHFFFAOYSA-N SMILES O=C(O)COc1nn(Cc2ccccc2)c2ccccc12 |
| Use of | Bendazac is an oxyacetic acid with anti-inflammatory, antinecrotic, choleretic and antilipidaemic properties. Bendazac acts by preventing protein denaturation and delays the cataractogenic process[1][2]. Properties Name bendazac Synonym More Synonyms Bendazac Biological Activity Description Bendazac is an oxyacetic acid with anti-inflammatory, antinecrotic, choleretic and antilipidaemic properties. Bendazac acts by preventing protein denaturation and delays the cataractogenic process[1][2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology In Vitro Bendazac is an anti-inflammatory agent endowed with protein antidenaturant properties effective for various inflammatory skin conditions. Bendazac has been shown to be a strong reacting substrate in a chemical oxidizing system, which mimics a physiological pathway of hydroxy radical generation[2]. By using EPR spectroscopy of spin-labelled bovine serum albumin (BSA), Bendazac was shown to prevent the BSA denaturation induced by urea, heat and free radicals produced in the xanthine/xanthine oxidase system[2]. References [1]. Balfour JA, et al. Bendazac lysine. A review of its pharmacological properties and therapeutic potential in the management of cataracts. Drugs. 1990;39(4):575-596. [2]. Guglielmotti A, et al. Radical scavenger activity of bendazac, an anticataract non-steroidal anti-inflammatory agent. Pharmacol Res. 1995;32(6):369-373. [3]. Musci G, et al. Mechanism of the scavenger-like activity of bendazac. Drugs Exp Clin Res. 1987;13(5):289-292. Chemical & Physical Properties Molecular Formula C16H14N2O3 Exact Mass 282.100433 PSA 64.35000 Index of Refraction 1.630 InChIKey BYFMCKSPFYVMOU-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 97.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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