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N-2-Acetylguanine structure, CAS 19962-37-9

N-2-Acetylguanine

CAS Number19962-37-9

Synonyms2-Acetamido-6-hydroxypurine; N2-Acetylguanine; N2-acetylguanidine; N-2-Acetylguanine; MFCD00078201; N-Acetylguanine; 2-acetylamino-6-hydroxypurine; 2-N-Acetylguanine; EINECS 243-443-7

Molecular FormulaC7H7O2N5

Molecular Weight193.16

Purity98.00%

Density1.83 g/cm3

Boiling Point

Melting Point260 °C

Flash Point

Appearancewhite solid

EINECS

MSDSChineseEnglish

Symbol

Signal Word

Cat. No.: 2A-9038269 Purity: 98.00%
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Quality Control of [ 19962-37-9 ] Purity: 98.00% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number19962-37-9
Catalog No.2A-9038269
Chinese NameN-2-乙酰鸟嘌呤
Synonyms2-Acetamido-6-hydroxypurine; N2-Acetylguanine; N2-acetylguanidine; N-2-Acetylguanine; MFCD00078201; N-Acetylguanine; 2-acetylamino-6-hydroxypurine; 2-N-Acetylguanine; EINECS 243-443-7
Molecular FormulaC7H7O2N5
Molecular Weight193.16
Purity98.00
Density1.83 g/cm3
Melting Point260 °C
Appearancewhite solid
Water Solubilitypractically insoluble
Storage ConditionStore in a sealed container in a cool, dry place
ApplicationN2 Acetylguanine is a C2 modified guanine s. N2 acetylguanine binds GR (guanine riboswitch) with a Kd value of 300 nM. N2 acetylguanine regulates transcription termination. N2 acetylguanine has the po
HTC2933990090
MDL NumberMFCD00067049
SMILESCC(=O)Nc1nc2nc[nH]c2c(=O)[nH]1
InChIInChI=1S/C7H7N5O2/c1-3(13)10-7-11-5-4(6(14)12-7)8-2-9-5/h2H,1H3,(H3,8,9,10,11,12,13,14)
InChI KeyMXSMRDDXWJSGMC-UHFFFAOYSA-N
MSDSmsds/38269_1_19962_37_9.pdf
BioactivityN2-Acetylguanine is a C2-modified guanine. N2-Acetylguanine binds GR (guanine-guanine riboswitch) with an Kd value of 300 nM. N2-Acetylguanine modulate transcriptional termination. N2-Acetylguanine has the potential for the research of antimicrobial agent[1]. Related Catalog Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis In Vitro N2-Acetylguanine completely disrupt a key Watson-Crick pairing interaction between the ligand and RNA[1]. N2-Acetylguanine (20 µM) promotes transcriptional termination in Bacillus subtilis [1]. References [1]. Matyjasik MM, et al. High Affinity Binding of N2-Modified Guanine Derivatives Significantly Disrupts the Ligand Binding Pocket of the Guanine Riboswitch. Molecules. 2020 May 13;25(10):2295. Chemical & Physical Properties Density 1.83 g/cm3 Melting Point 260 °C Molecular Formula C7H7N5O2 Molecular Weight 193.16300 Exact Mass 193.06000 PSA 103.53000 Index of Refraction 1.833 InChIKey MXSMRDDXWJSGMC-UHFFFAOYSA-N SMILES CC(=O)Nc1nc2nc[nH]c2c(=O)[nH]1 Storage condition Refrigerator Water Solubility practically insoluble
Use ofN2-Acetylguanine is a C2-modified guanine. N2-Acetylguanine binds GR (guanine-guanine riboswitch) with an Kd value of 300 nM. N2-Acetylguanine modulate transcriptional termination. N2-Acetylguanine has the potential for the research of antimicrobial agent[1]. Properties Name N-(6-oxo-3,7-dihydropurin-2-yl)acetamide Synonym More Synonyms N-2-Acetylguanine Biological Activity Description N2-Acetylguanine is a C2-modified guanine. N2-Acetylguanine binds GR (guanine-guanine riboswitch) with an Kd value of 300 nM. N2-Acetylguanine modulate transcriptional termination. N2-Acetylguanine has the potential for the research of antimicrobial agent[1]. Related Catalog Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis In Vitro N2-Acetylguanine completely disrupt a key Watson-Crick pairing interaction between the ligand and RNA[1]. N2-Acetylguanine (20 µM) promotes transcriptional termination in Bacillus subtilis [1]. References [1]. Matyjasik MM, et al. High Affinity Binding of N2-Modified Guanine Derivatives Significantly Disrupts the Ligand Binding Pocket of the Guanine Riboswitch. Molecules. 2020 May 13;25(10):2295. Chemical & Physical Properties Molecular Formula C7H7N5O2 Exact Mass 193.06000 PSA 103.53000 Index of Refraction 1.833 InChIKey MXSMRDDXWJSGMC-UHFFFAOYSA-N Storage condition Refrigerator Water Solubility practically insoluble
Tax Rebate13.0%
SupervisionNone. MFN tariff: 6.5%. Ordinary tariff: 20.0%
Transport InfoProduct name: Purity: 95.0%
MSDS Transport InfoModule 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified
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