CAS Number19388-87-5
Synonyms4,4'-Methylenebis(tetrahydro-1,2,4-thiadiazine) 1,1,1',1'-tetraoxide; 4,4'-methanediylbis(1,2,4-thiadiazinane) 1,1,1',1'-tetraoxide; 2H-1,2,4-Thiadiazine, 4,4'-methylenebis[tetrahydro-, 1,1,1',1'-tetraoxide; 4,4'-Methylenebis(tetrahydro-1,2,4-sulfadiazine 1,1-dioxide); 4,4'-Methylenebis(perhydro-1,2,4-thiadiazine 1,1-dioxide); Bis(1,1-dioxoperhydro-1,2,4-thiadiazin-4-yl)methane; 4,4'-Methylenebis(1,2,4-thiadiazinane) 1,1,1',1'-tetraoxide; Taurolin; Taurolidine; Tauroline
Molecular FormulaC7H16N4O4S2
Molecular Weight284.36
Purity>97 (NMR)%
Density1.5±0.1 g/cm3
Boiling Point471.2±55.0 °C at 760 mmHg
Melting Point156ºC
Appearancepowder
EINECS243-016-5
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 19388-87-5 |
| Catalog No. | 2A-9038094 |
| Chinese Name | 牛磺罗定 |
| Synonyms | 4,4'-Methylenebis(tetrahydro-1,2,4-thiadiazine) 1,1,1',1'-tetraoxide; 4,4'-methanediylbis(1,2,4-thiadiazinane) 1,1,1',1'-tetraoxide; 2H-1,2,4-Thiadiazine, 4,4'-methylenebis[tetrahydro-, 1,1,1',1'-tetraoxide; 4,4'-Methylenebis(tetrahydro-1,2,4-sulfadiazine 1,1-dioxide); 4,4'-Methylenebis(perhydro-1,2,4-thiadiazine 1,1-dioxide); Bis(1,1-dioxoperhydro-1,2,4-thiadiazin-4-yl)methane; 4,4'-Methylenebis(1,2,4-thiadiazinane) 1,1,1',1'-tetraoxide; Taurolin; Taurolidine; Tauroline |
| Molecular Formula | C7H16N4O4S2 |
| Molecular Weight | 284.36 |
| Purity | >97 (NMR) |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 471.2±55.0 °C at 760 mmHg |
| Melting Point | 156ºC |
| Appearance | powder |
| Storage Condition | 0-10°C; store in inert gas; avoid light, air, heat |
| Application | Taurolidine is a broad-spectrum antimicrobial agent used to prevent central venous catheter-related infections. Taurolidine can have direct and selective anti-tumor effects on brain tumor cells by ind |
| EINECS | 243-016-5 |
| HTC | 2933990090 |
| PubChem ID | 329826864 |
| MDL Number | MFCD00865076 |
| SMILES | O=S1(=O)CCN(CN1)CN2CCS(=O)(=O)NC2 |
| InChI | 1S/C7H16N4O4S2/c12-16(13)3-1-10(5-8-16)7-11-2-4-17(14,15)9-6-11/h8-9H,1-7H2 |
| InChI Key | AJKIRUJIDFJUKJ-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| Hazard Symbols | transportation |
| MSDS | msds/38094_1_19388_87_5.pdf |
| Bioactivity | Taurolidine is a broad-spectrum antimicrobial for the prevention of central venous catheter-related infections. Taurolidine has a direct and selective antineoplastic effect on brain tumor cells by the induction of apoptosis[1]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial References [1]. Haro C, et al. Taurolidine, an antiseptic for the prevention of central venous catheter-related infections. Rev Chilena Infectol. 2019 Aug;36(4):414-420. [2]. Stendel R, et al. Treatment of glioblastoma with intravenous taurolidine. First clinical experience. Anticancer Res. 2004 Mar-Apr;24(2C):1143-7. Chemical & Physical Properties Density 1.5±0.1 g/cm3 Boiling Point 471.2±55.0 °C at 760 mmHg Melting Point 156ºC Molecular Formula C7H16N4O4S2 Molecular Weight 284.356 Flash Point 238.8±31.5 °C Exact Mass 284.061310 PSA 115.58000 LogP -2.55 Vapour Pressure 0.0±1.2 mmHg at 25°C Index of Refraction 1.564 InChIKey AJKIRUJIDFJUKJ-UHFFFAOYSA-N SMILES O=S1(=O)CCN(CN2CCS(=O)(=O)NC2)CN1 |
| Use of | Taurolidine is a broad-spectrum antimicrobial for the prevention of central venous catheter-related infections. Taurolidine has a direct and selective antineoplastic effect on brain tumor cells by the induction of apoptosis[1]. Properties Articles34 Name Taurolidine Synonym More Synonyms Taurolidine Biological Activity Description Taurolidine is a broad-spectrum antimicrobial for the prevention of central venous catheter-related infections. Taurolidine has a direct and selective antineoplastic effect on brain tumor cells by the induction of apoptosis[1]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial References [1]. Haro C, et al. Taurolidine, an antiseptic for the prevention of central venous catheter-related infections. Rev Chilena Infectol. 2019 Aug;36(4):414-420. Chemical & Physical Properties Molecular Formula C7H16N4O4S2 Exact Mass 284.061310 PSA 115.58000 LogP -2.55 Index of Refraction 1.564 InChIKey AJKIRUJIDFJUKJ-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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