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Triethylene glycol di(p-toluenesulfonate) structure, CAS 19249-03-7

Triethylene glycol di(p-toluenesulfonate)

CAS Number19249-03-7

SynonymsEthanol, 2,2'-(1,2-ethanediylbis(oxy))bis-, bis(4-methylbenzenesulfonate); 1,2-Ethanediylbis(oxy-2,1-ethanediyl) bis(4-methylbenzenesulfonate); 2-[2-(2-([(4-Methylphenyl)sulfonyl]oxy)ethoxy)ethoxy]ethyl 4-methylbenzenesulfonate; TRI(ETHYLENE GLYCOL) DI-P-TOLUENESULFONATE; ethane-1,2-diylbis(oxyethane-2,1-diyl) bis(4-methylbenzenesulfonate); Triethylene Glycol Bis(p-toluenesulfonate); Triethylene glycol di(p-toluenesulfonate); Triethylene Glycol Di-p-tosylate; triethylene glycol bis(4-toluenesulfonate); 1,2-Bis(2-tosyloxyethoxy)ethane; Ethanol, 2,2'-[1,2-ethanediylbis(oxy)]bis-, bis(4-methylbenzenesulfonate); bis-tosylated triethyleneglycol; MFCD00048096; Triethylene glycol ditosylate; 1,2-Bis[2-(p-toluenesulfonyloxy)ethoxy]ethane; 2,2'-(Ethylenedioxy)diethyl Ditosylate; (Ethane-1,2-diylbis

Molecular Formula(CH3C6H4SO3CH2CH2OCH2-)2

Molecular Weight458.55

Purity98%

Density1.3±0.1 g/cm3

Boiling Point608.4±55.0 °C at 760 mmHg

Melting Point78-82 °C (lit.)

Flash Point

AppearanceWhite

EINECS

MSDSChineseEnglish

Symboltransportation

Signal WordWarning

Cat. No.: 2A-9038061 Purity: 98%
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Quality Control of [ 19249-03-7 ] Purity: 98% SDS Specification MoL

Chemical & Physical Properties
CAS Number19249-03-7
Catalog No.2A-9038061
Chinese Name三乙二醇二对甲苯磺酸酯
SynonymsEthanol, 2,2'-(1,2-ethanediylbis(oxy))bis-, bis(4-methylbenzenesulfonate); 1,2-Ethanediylbis(oxy-2,1-ethanediyl) bis(4-methylbenzenesulfonate); 2-[2-(2-([(4-Methylphenyl)sulfonyl]oxy)ethoxy)ethoxy]ethyl 4-methylbenzenesulfonate; TRI(ETHYLENE GLYCOL) DI-P-TOLUENESULFONATE; ethane-1,2-diylbis(oxyethane-2,1-diyl) bis(4-methylbenzenesulfonate); Triethylene Glycol Bis(p-toluenesulfonate); Triethylene glycol di(p-toluenesulfonate); Triethylene Glycol Di-p-tosylate; triethylene glycol bis(4-toluenesulfonate); 1,2-Bis(2-tosyloxyethoxy)ethane; Ethanol, 2,2'-[1,2-ethanediylbis(oxy)]bis-, bis(4-methylbenzenesulfonate); bis-tosylated triethyleneglycol; MFCD00048096; Triethylene glycol ditosylate; 1,2-Bis[2-(p-toluenesulfonyloxy)ethoxy]ethane; 2,2'-(Ethylenedioxy)diethyl Ditosylate; (Ethane-1,2-diylbis
Molecular Formula(CH3C6H4SO3CH2CH2OCH2-)2
Molecular Weight458.55
Purity98
Density1.3±0.1 g/cm3
Boiling Point608.4±55.0 °C at 760 mmHg
Melting Point78-82 °C (lit.)
AppearanceWhite
Storage ConditionSealed at room temperature, protected from light,
ApplicationTriethylene glycol bis(p-toluenesulfonate) is a PROTAC linker, belonging to the PEG class. Can be used to synthesize PROTAC molecules.
HTC2909309090
PubChem ID24860606
MDL NumberMFCD00048096
SMILESCc1ccc(cc1)S(=O)(=O)OCCOCCOCCOS(=O)(=O)c2ccc(C)cc2
InChI1S/C20H26O8S2/c1-17-3-7-19(8-4-17)29(21,22)27-15-13-25-11-12-26-14-16-28-30(23,24)20-9-5-18(2)6-10-20/h3-10H,11-16H2,1-2H3
InChI KeyKCONMNWPRXAWKK-UHFFFAOYSA-N
Beilstein/REAXYS632509
NACRES CodeNA.22
UNSPSC12352100
Hazard Symbolstransportation
MSDSmsds/38061_1_19249_03_7.pdf
BioactivityTriethylene glycol bis(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 608.4±55.0 °C at 760 mmHg Melting Point 78-82 °C(lit.) Molecular Formula C20H26O8S2 Molecular Weight 458.546 Flash Point 321.7±31.5 °C Exact Mass 458.106903 PSA 121.96000 LogP 2.34 Vapour Pressure 0.0±1.7 mmHg at 25°C Index of Refraction 1.545 InChIKey KCONMNWPRXAWKK-UHFFFAOYSA-N SMILES Cc1ccc(S(=O)(=O)OCCOCCOCCOS(=O)(=O)c2ccc(C)cc2)cc1
Use ofTriethylene glycol bis(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Properties Name 2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethyl 4-methylbenzenesulfonate Synonym More Synonyms Biological Activity Description Triethylene glycol bis(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. Chemical & Physical Properties Molecular Formula C20H26O8S2 Exact Mass 458.106903 PSA 121.96000 Index of Refraction 1.545 InChIKey KCONMNWPRXAWKK-UHFFFAOYSA-N
Tax Rebate9.0%
Supervisionnone
Transport InfoProduct name: Purity: 0.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available
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