CAS Number19130-96-2
Synonyms(2R,3R,4R,5S)-2-Hydroxymethyl-3,4,5-trihydroxypiperidine; D-5-Amino-1,5-dideoxyglucopyranose; deoxynojirimycin; MFCD00063474; MORANOLINE; (2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-triol; Duvoglustat; (2R,3R,4R,5S)-2-(Hydroxymethyl)-3,4,5-piperidinetriol; 1,5-Dideoxy-1,5-imino-D-glucitol; (+)-1-deoxynojirimycin; 1-Deoxy-Nojirimycin; desoxynojirimycin; (2R,3R,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-triol; S-GI; [2R-(2a,3b,4a,5b)]-2-(Hydroxymethyl)-3,4,5-piperidinetriol
Molecular FormulaC6H13NO4
Molecular Weight163.17
Purity≥90.0 (HPLC)%
Density1.5±0.1 g/cm3
Boiling Point361.1±42.0 °C at 760 mmHg
Melting Point195-196°C
Appearancewhite solid
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| Chemical & Physical Properties | |
|---|---|
| CAS Number | 19130-96-2 |
| Catalog No. | 2A-9038023 |
| Chinese Name | 1-脱氧野尻霉素 |
| Synonyms | (2R,3R,4R,5S)-2-Hydroxymethyl-3,4,5-trihydroxypiperidine; D-5-Amino-1,5-dideoxyglucopyranose; deoxynojirimycin; MFCD00063474; MORANOLINE; (2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-triol; Duvoglustat; (2R,3R,4R,5S)-2-(Hydroxymethyl)-3,4,5-piperidinetriol; 1,5-Dideoxy-1,5-imino-D-glucitol; (+)-1-deoxynojirimycin; 1-Deoxy-Nojirimycin; desoxynojirimycin; (2R,3R,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-triol; S-GI; [2R-(2a,3b,4a,5b)]-2-(Hydroxymethyl)-3,4,5-piperidinetriol |
| Molecular Formula | C6H13NO4 |
| Molecular Weight | 163.17 |
| Purity | ≥90.0 (HPLC) |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 361.1±42.0 °C at 760 mmHg |
| Melting Point | 195-196°C |
| Appearance | white solid |
| Storage Condition | Desiccate at +4°C |
| Application | 1-Deoxynojirimycin (DNJ, Duvoglustat) is a potent alpha-glucosidase inhibitor that suppresses postprandial blood sugar, thereby preventing diabetes. |
| HTC | 2933399090 |
| PubChem ID | 29435 |
| MDL Number | MFCD00063474 |
| SMILES | OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O |
| InChI | 1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1 |
| InChI Key | LXBIFEVIBLOUGU-JGWLITMVSA-N |
| Beilstein/REAXYS | 3588039 |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/38023_1_19130_96_2.pdf |
| Use of | 1-Deoxynojirimycin (DNJ, Duvoglustat) is a potent α-glucosidase inhibitor, suppresses postprandial blood glucose, thereby possibly preventing diabetes mellitus. Target: α-glucosidase1-Deoxynojirimycin is an alpha-glucosidase inhibitor, most commonly found in mulberry leaves. Although it can be obtained in small quantities by brewing an herbal tea from mulberry leaves, interest in commercial production has led to research on developing mulberry tea higher in DNJ, and on alternate routes of production, such as via Bacillusspecies. Properties Name duvoglustat Synonym More Synonyms 1-Deoxynojirimycin Biological Activity Description 1-Deoxynojirimycin (DNJ, Duvoglustat) is a potent α-glucosidase inhibitor, suppresses postprandial blood glucose, thereby possibly preventing diabetes mellitus. Target: α-glucosidase1-Deoxynojirimycin is an alpha-glucosidase inhibitor, most commonly found in mulberry leaves. Although it can be obtained in small quantities by brewing an herbal tea from mulberry leaves, interest in commercial production has led to research on developing mulberry tea higher in DNJ, and on alternate routes of production, such as via Bacillusspecies. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease References [1]. Chaluntorn Vichasilp,et al. Development of high 1-deoxynojirimycin (DNJ) content mulberry tea and use of response surface methodology to optimize tea-making conditions for highest DNJ extraction. LWT - Food Science and Technology. Volume 45, Issue 2, Marc Chemical & Physical Properties Molecular Formula C6H13NO4 Exact Mass 163.084457 PSA 92.95000 LogP -2.10 Index of Refraction 1.582 InChIKey LXBIFEVIBLOUGU-UHFFFAOYSA-N SMILES OCC1NCC(O)C(O)C1O Safety Information Hazard Codes Xi WGK Germany 3 HS Code 2933399090 Synthetic Route 149302-60-3 1-Deoxynojirimy... 19130-96-2 Literature: Zhang, Zhen-Xing; Wu, Baolin; Wang, Bin; Li, Tie-Hai; Zhang, Peng-Fei; Guo, Li-Na; Wang, Wen-Jun; Zhao, Wei; Wang, Peng George Tetrahedron Letters, 2011 , vol. 52, # 29 p. 3802 - 3804 N-Benzhydryl-1-... 132198-14-2 1-Deoxynojirimy... 19130-96-2 Literature: Baxter; Reitz Journal of Organic Chemistry, 1994 , vol. 59, # 11 p. 3175 - 3185 Vinbarbital 75016-28-3 1-Deoxynojirimy... 19130-96-2 Literature: Kinast; Schedel Angewandte Chemie, 1981 , vol. 93, # 9 p. 799 - 800 Precursor & DownStream Precursor 6 CAS#:132198-14-2 N-Benzhydryl-1-... CAS#:75016-28-3 Vinbarbital CAS#:69567-11-9 Deoxynojirimyci... CAS#:15218-38-9 nojirimycin DownStream 10 CAS#:80312-32-9 4-O-α-D-Glucopy... CAS#:72432-03-2 CAS#:72599-27-0 CAS#:69567-10-8 N-Methylmoranoline |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| Location | Store as supplied at 0-4° C for up to 1 year. Store solutions at -20° C for up to 3 months. |
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