CAS Number17817-31-1
SynonymsDemethyltexasin; 6,7,4'-trihydroxyisoflavone; 6,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one; 4',6,7-trihydroxy-isoflavone; 6-hydroxydaidziein; 6-Hydroxydaidzein; MFCD00016953; 6,7,4'-trihydroxyisoflavon; 6,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one
Molecular FormulaC15H10O5
Molecular Weight270.24
Purity≥95%
Density1.548g/cm3
Boiling Point587.1ºC at 760mmHg
Melting Point320 °C
Appearancepowder or crystals
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 17817-31-1 |
| Catalog No. | 2A-9037644 |
| Chinese Name | 6,7,4'-三羟基异黄酮 |
| Synonyms | Demethyltexasin; 6,7,4'-trihydroxyisoflavone; 6,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one; 4',6,7-trihydroxy-isoflavone; 6-hydroxydaidziein; 6-Hydroxydaidzein; MFCD00016953; 6,7,4'-trihydroxyisoflavon; 6,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one |
| Molecular Formula | C15H10O5 |
| Molecular Weight | 270.24 |
| Purity | ≥95 |
| Density | 1.548g/cm3 |
| Boiling Point | 587.1ºC at 760mmHg |
| Melting Point | 320 °C |
| Appearance | powder or crystals |
| Water Solubility | Soluble in: dimethylformamide |
| Storage Condition | room temperature |
| Application | Desmethylglycitein (4',6,7-Trihydroxyisoflavone), a metabolite of daidzein, derived from soybean Glycine max, has antioxidant and anticancer activities. Desmethylglycitein directly binds CDK1 and CDK2 |
| HTC | 2914501900 |
| PubChem ID | 801128 |
| MDL Number | MFCD00016953 |
| SMILES | C1=CC(=CC=C1C2=COC3=CC(=C(C=C3C2=O)O)O)O |
| InChI | InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-14-6-13(18)12(17)5-10(14)15(11)19/h1-7,16-18H |
| InChI Key | GYLUFQJZYAJQDI-UHFFFAOYSA-N |
| Beilstein/REAXYS | 1291621 |
| NACRES Code | NA.21 |
| UNSPSC | 12352200 |
| MSDS | msds/37644_1_17817_31_1.pdf |
| Use of | Desmethylglycitein (4',6,7-Trihydroxyisoflavone), a metabolite of daidzein, sourced from Glycine max with antioxidant, and anti-cancer activities.Desmethylglycitein binds directly to CDK1 and CDK2 in vivo, resulting in the suppresses CDK1 and CDK2 activity[1]. Desmethylglycitein is a direct inhibitor of protein kinase C (PKC)α, against solar UV (sUV)-induced matrix matrix metalloproteinase 1 (MMP1)[2]. Desmethylglycitein binds to PI3K in an ATP competitive manner in the cytosol, where it inhibits the activity of PI3K and downstream signaling cascades, leading to the suppression of adipogenesis in 3T3-L1 preadipocytes[3]. Properties Biological Activity Chemical & Physical Properties Safety Info Synthetic Route Precursor & Downstream |
| Tax Rebate | 9.0% |
| Supervision | none |
| Transport Info | Product name: Summary 2914501900 other ketone-phenols. Supervision conditions:None. VAT: 17.0%. Tax rebate rate:9.0%. MFN tariff:5.5%. General tariff:30.0% |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| 1-(4-Bromophenyl)-1-methylethylamine | 17797-12-5 | 2A-9037636 |
| 3,4-Dimethyldiphenylamine | 17802-36-7 | 2A-9037637 |
| trans-3-Benzoylacrylic acid | 17812-07-6 | 2A-9037640 |
| 1-Methyl L-aspartate | 17812-32-7 | 2A-9037641 |
| 2-Amino-4(5H)-oxazolone | 17816-85-2 | 2A-9037642 |
| Tetra(ethylene glycol) diacrylate | 17831-71-9 | 2A-9037647 |
| Methyl 3-(aminomethyl)benzoate hydrochloride | 17841-68-8 | 2A-9037649 |
| 2-Chlorobenzyl alcohol | 17849-38-6 | 2A-9037651 |
| 4-Hydrazinobenzene-1-sulfonamide hydrochloride | 17852-52-7 | 2A-9037652 |
| 4-(Methylsulfonyl)phenylhydrazine hydrochloride | 17852-67-4 | 2A-9037653 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS