
CAS Number253128-41-5
SynonymsEribulin; (1S,3S,4R)-3-tert-butoxycarbonylamino-4-hydroxycyclopentanecarboxylic acid methyl ester; NSC-707389; Methyl(1S,3S,4R)NBOC3amino4hydroxycyclopentanecarboxylate; Halaven; ER-086526
Molecular FormulaC40H59NO11
Molecular Weight729.90
Purity≥98 (HPLC)%
Density1.29±0.1 g/cm3
Appearancepowder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 253128-41-5 |
| Catalog No. | 2A-9035030 |
| Chinese Name | 艾日布林 |
| Synonyms | Eribulin; (1S,3S,4R)-3-tert-butoxycarbonylamino-4-hydroxycyclopentanecarboxylic acid methyl ester; NSC-707389; Methyl(1S,3S,4R)NBOC3amino4hydroxycyclopentanecarboxylate; Halaven; ER-086526 |
| Molecular Formula | C40H59NO11 |
| Molecular Weight | 729.90 |
| Purity | ≥98 (HPLC) |
| Density | 1.29±0.1 g/cm3 |
| Appearance | powder |
| Water Solubility | Practically insoluble (0.015 g/L) (25 ºC) |
| Storage Condition | 2-8℃ |
| Application | Eribulin (E7389; ER-086526) is a synthetic halichondrin B analog that can bind to tubulin and microtubules and has entered Phase III clinical trials against breast cancer. |
| PubChem ID | 16446284 |
| SMILES | C=C1CC2CCC34CC5OC6C(OC7CCC(CC(=O)CC8C(CC9OC(CCC1O2)CC(C)C9=C)OC(CC(O)CN)C8OC)OC7C6O3)C5O4 |
| InChI | InChI=1S/C40H59NO11/c1-19-11-24-5-7-28-20(2)12-26(45-28)9-10-40-17-33-36(51-40)37-38(50-33)39(52-40)35-29(49-37)8-6-25(47-35)13-22(42)14-27-31(16-30(46-24)21(19)3)48-32(34(27)44-4)15-23(43)18-41/h19,23-39,43H,2-3,5-18,41H2,1,4H3/t19-,23+,24+,25-,26+,27+,28+,29+,30-,31+,32-,33-,34-,35+,36+,37+,38-,39+,40+/m1/s1 |
| InChI Key | UFNVPOGXISZXJD-JBQZKEIOSA-N |
| NACRES Code | NA.21 |
| MSDS | msds/35030_1_253128_41_5.pdf |
| Transport Info | Product name: Eribulin |
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