CAS Number9041-22-9
Synonymsβ-D-Glucopyranosyl-(1->4)-(4ξ)-β-D-xylo-hexopyranosyl-(1->4)-(4ξ)-α-D-xylo-hexopyranose; Carbamic acid,(1,1-dimethyl-2-propynyl)-,2-fluoroethyl ester; beta-D-Glucan
Molecular Formula(C6H10O5)n
Molecular Weight504.437
Purity98.00%
Density1.8±0.1 g/cm3
Boiling Point865.2±65.0 °C at 760 mmHg
Appearancepowder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 9041-22-9 |
| Catalog No. | 2A-9034502 |
| Chinese Name | β-D-葡聚糖 来源于大麦 |
| Synonyms | β-D-Glucopyranosyl-(1->4)-(4ξ)-β-D-xylo-hexopyranosyl-(1->4)-(4ξ)-α-D-xylo-hexopyranose; Carbamic acid,(1,1-dimethyl-2-propynyl)-,2-fluoroethyl ester; beta-D-Glucan |
| Molecular Formula | (C6H10O5)n |
| Molecular Weight | 504.437 |
| Purity | 98.00 |
| Density | 1.8±0.1 g/cm3 |
| Boiling Point | 865.2±65.0 °C at 760 mmHg |
| Appearance | powder |
| Water Solubility | H2O: 20 mg/mL, clear, faintly yellow |
| Storage Condition | 2-8°C |
| Application | β-D-glucan is a natural non-digestible polysaccharide with high biocompatibility, can be selectively recognized by recognition receptors such as Dectin-1 and Toll-like receptors, and is easily endocyt |
| PubChem ID | 329799962 |
| SMILES | OCC1OC(OC2C(CO)OC(OC3C(CO)OC(O)C(O)C3O)C(O)C2O)C(O)C(O)C1O |
| InChI | InChI=1S/C18H32O16/c19-1-4-7(22)8(23)12(27)17(31-4)34-15-6(3-21)32-18(13(28)10(15)25)33-14-5(2-20)30-16(29)11(26)9(14)24/h4-29H,1-3H2/t4-,5-,6-,7-,8+,9-,10-,11-,12-,13-,14?,15?,16+,17+,18+/m1/s1 |
| InChI Key | FYGDTMLNYKFZSV-URKRLVJHSA-N |
| Hazard Symbols | transportation |
| Bioactivity | β-D-glucan is a natural non-digestible polysaccharide and high biocompatibility that can be selectively recognized by recognition receptors such as Dectin-1 and Toll-like receptors as well as being easily internalized by murine or human macrophages, which is likely to attribute to a target delivery[1]. β-d-glucan is an enteric delivery vehicle for probiotics[2]. Related Catalog Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR) Research Areas >> Cancer In Vitro β-D-glucan dissolved in DMSO but not water inhibits MCF-7 cell proliferation in a concentration-dependent manner as measured by BrdU incorporation with an IC50 of ∼164 μg/mL. β-D-glucan dissolved in DMSO inhibits tamoxifen/endocrine-resistant LCC9 and LY2 cell proliferation with IC50 values of 4.6 and 24.2 μg/mL, respectively[3]. References [1]. Su Y, et al. pH-sensitive PEG-coated hyper-branched β-d-glucan derivative as carrier for CpG oligodeoxynucleotide delivery. Carbohydr Polym. 2020;246:116621. [2]. Gani A, et al. β-d-glucan as an enteric delivery vehicle for probiotics. Int J Biol Macromol. 2018;106:864-869. [3]. Jafaar ZM, et al. β-D-glucan inhibits endocrine-resistant breast cancer cell proliferation and alters gene expression. Int J Oncol. 2014;44(4):1365-1375. Chemical & Physical Properties Density 1.8±0.1 g/cm3 Boiling Point 865.2±65.0 °C at 760 mmHg Molecular Formula C18H32O16 Molecular Weight 504.437 Flash Point 477.0±34.3 °C Exact Mass 504.169037 PSA 268.68000 LogP -3.25 Appearance of Characters powder Vapour Pressure 0.0±0.6 mmHg at 25°C Index of Refraction 1.673 InChIKey FYGDTMLNYKFZSV-URKRLVJHSA-N SMILES OCC1OC(OC2C(CO)OC(OC3C(CO)OC(O)C(O)C3O)C(O)C2O)C(O)C(O)C1O Storage condition 2-8°C Water Solubility H2O: 20 mg/mL, clear, faintly yellow |
| Use of | β-D-glucan is a natural non-digestible polysaccharide and high biocompatibility that can be selectively recognized by recognition receptors such as Dectin-1 and Toll-like receptors as well as being easily internalized by murine or human macrophages, which is likely to attribute to a target delivery[1]. β-d-glucan is an enteric delivery vehicle for probiotics[2]. Properties Name β-D-Glucan Synonym More Synonyms beta-D-Glucan Biological Activity Description β-D-glucan is a natural non-digestible polysaccharide and high biocompatibility that can be selectively recognized by recognition receptors such as Dectin-1 and Toll-like receptors as well as being easily internalized by murine or human macrophages, which is likely to attribute to a target delivery[1]. β-d-glucan is an enteric delivery vehicle for probiotics[2]. Related Catalog Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR) Research Areas >> Cancer References [1]. Su Y, et al. pH-sensitive PEG-coated hyper-branched β-d-glucan derivative as carrier for CpG oligodeoxynucleotide delivery. Carbohydr Polym. 2020;246:116621. [2]. Gani A, et al. β-d-glucan as an enteric delivery vehicle for probiotics. Int J Biol Macromol. 2018;106:864-869. [3]. Jafaar ZM, et al. β-D-glucan inhibits endocrine-resistant breast cancer cell proliferation and alters gene expression. Int J Oncol. 2014;44(4):1365-1375. Chemical & Physical Properties Molecular Formula C18H32O16 Exact Mass 504.169037 PSA 268.68000 LogP -3.25 Appearance of Characters powder Index of Refraction 1.673 InChIKey FYGDTMLNYKFZSV-URKRLVJHSA-N |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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