CAS Number8001-54-5
SynonymsBenzenemethanaminium, N,N-dimethyl-N-tridecyl-, chloride (1:1); MFCD00050250; N-Benzyl-N,N-dimethyltridecan-1-aminium chloride; EINECS 264-151-6; N-Benzyl-N,N-dimethyl-1-tridecanaminium chloride; Alkyldimethylbenzylammonium Chloride; Benzalkonium Chloride
Molecular FormulaC6H5CH2N(CH3)2RCl(R=C8H17toC18H37)
Molecular Weight354.013
Purity98.00%
Density0.98
Boiling Point>100°C/760mmHg
AppearanceLight yellow liquid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 8001-54-5 |
| Catalog No. | 2A-9034201 |
| Chinese Name | 苯扎氯铵 |
| Synonyms | Benzenemethanaminium, N,N-dimethyl-N-tridecyl-, chloride (1:1); MFCD00050250; N-Benzyl-N,N-dimethyltridecan-1-aminium chloride; EINECS 264-151-6; N-Benzyl-N,N-dimethyl-1-tridecanaminium chloride; Alkyldimethylbenzylammonium Chloride; Benzalkonium Chloride |
| Molecular Formula | C6H5CH2N(CH3)2RCl(R=C8H17toC18H37) |
| Molecular Weight | 354.013 |
| Purity | 98.00 |
| Density | 0.98 |
| Boiling Point | >100°C/760mmHg |
| Appearance | Light yellow liquid |
| Storage Condition | Packed in plastic barrels and stored in a cool and |
| Packaging | javascript:void(0); |
| Application | Benzalkonium chloride is a potent antimicrobial agent used as a preservative in eye drops. |
| PubChem ID | 8150005 |
| MDL Number | MFCD00145757 |
| SMILES | [Cl-].[N+](CCCCCCCCCC)(Cc1ccccc1)(C)C |
| InChI | 1S/C19H34N.ClH/c1-4-5-6-7-8-9-10-14-17-20(2,3)18-19-15-12-11-13-16-19;/h11-13,15-16H,4-10,14,17-18H2,1-3H3;1H/q+1;/p-1 |
| InChI Key | TTZLKXKJIMOHHG-UHFFFAOYSA-M |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/34201_1_8001_54_5.pdf |
| Bioactivity | Benzalkonium chloride is a potent anti-microbial agent, used as a preservative in eye drops. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection In Vitro Benzalkonium chloride (0.0001%-0.5%) results in a dose-dependent cytotoxicity in cells. Benzalkonium chloride also shows cytotoxicity against human keratinocytes, with 50% loss of viability of 4 μM. Benzalkonium chloride shows different results in NHEK and NB1RGB cell cultures, and the ED50 of 3.9 and 62 μM, respectively. The clinically used concentration (0.01% Benzalkonium chloride) significantly reduces cell viability, with only 14%-19% of nasal epithelial cells surviving the treatment[1]. In Vivo Benzalkonium chloride (0.02%) causes no abnormalities in the nasal epithelium of the monkeys after light and electron microscopical examination. In 4-5 week-old SD rats, 0.01% and 0.1% Benzalkonium chloride induce a time-dependent increase in the thickness of the nasal respiratory epithelium[1]. References [1]. Johnson NF. Pulmonary Toxicity of Benzalkonium Chloride. J Aerosol Med Pulm Drug Deliv. 2017 Jul 6. Chemical & Physical Properties Density 0.98 Boiling Point >100°C/760mmHg Molecular Formula C6H5CH2N(CH3)2RCl(R=C8H17toC18H37) Molecular Weight 354.013 Exact Mass 353.284943 LogP 7.76610 Storage condition 2-8°C Stability Stable. Incompatible with strong oxidizing agents, moisture. Hygroscopic. |
| Use of | Benzalkonium chloride is a potent anti-microbial agent, used as a preservative in eye drops. Properties Name benzalkonium chloride Synonym More Synonyms Benzalkonium chloride Biological Activity Description Benzalkonium chloride is a potent anti-microbial agent, used as a preservative in eye drops. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection In Vitro Benzalkonium chloride (0.0001%-0.5%) results in a dose-dependent cytotoxicity in cells. Benzalkonium chloride also shows cytotoxicity against human keratinocytes, with 50% loss of viability of 4 μM. Benzalkonium chloride shows different results in NHEK and NB1RGB cell cultures, and the ED50 of 3.9 and 62 μM, respectively. The clinically used concentration (0.01% Benzalkonium chloride) significantly reduces cell viability, with only 14%-19% of nasal epithelial cells surviving the treatment[1]. In Vivo Benzalkonium chloride (0.02%) causes no abnormalities in the nasal epithelium of the monkeys after light and electron microscopical examination. In 4-5 week-old SD rats, 0.01% and 0.1% Benzalkonium chloride induce a time-dependent increase in the thickness of the nasal respiratory epithelium[1]. References [1]. Johnson NF. Pulmonary Toxicity of Benzalkonium Chloride. J Aerosol Med Pulm Drug Deliv. 2017 Jul 6. Chemical & Physical Properties Exact Mass 353.284943 LogP 7.76610 Stability Stable. Incompatible with strong oxidizing agents, moisture. Hygroscopic. |
| Transport Info | Product Name: Benzalkonium Chloride |
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