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Riboprine structure, CAS 7724-76-7

Riboprine

CAS Number7724-76-7

SynonymsN-(3-Methyl-2-buten-1-yl)adenosine; N-(3-Methylbut-2-en-1-yl)adenosine; N6-(δ2-Isopentenyl)adenosine; 6-(g,g-Dimethylallylamino)purine Riboside; N-6-(δ-2-Isopentenyl)adenosine; isopentenyl-Adenosine-[d6]; riboprina; 6-N-((3-Methyl-2-butenyl)amino)-9-b-D-ribofuranosyl-9H-purine; N6-isopentenyladenosine; 6-(γ,γ-Dimethylallylamino)purine riboside; riboprine; N6-ISOPENTENYLADENOSINE-D6; isopentenyladenosine; riboprinum; Isopentenyl-Adenosine; N(6)-(δ(2)-isopentenyl)adenosine; 2-IP RIBOSIDE; EINECS 231-771-3; N6-(D2-Isopentenyl)adenosine; N-6-(δ-2-Isopentenyl)adenosinehemihydrate; 2ipa; N(6)-(Delta(2)-isopentenyl)adenosine; n-isopentenyladenosine; MFCD00005741

Molecular FormulaC15H21O4N5

Molecular Weight335.36

Purity98.00%

Density1.6±0.1 g/cm3

Boiling Point647.2±65.0 °C at 760 mmHg

Melting Point143-146°C

Flash Point

Appearance

EINECS

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Cat. No.: 2A-9033953 Purity: 98.00%
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Quality Control of [ 7724-76-7 ] Purity: 98.00% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number7724-76-7
Catalog No.2A-9033953
Chinese Name利波腺苷
SynonymsN-(3-Methyl-2-buten-1-yl)adenosine; N-(3-Methylbut-2-en-1-yl)adenosine; N6-(δ2-Isopentenyl)adenosine; 6-(g,g-Dimethylallylamino)purine Riboside; N-6-(δ-2-Isopentenyl)adenosine; isopentenyl-Adenosine-[d6]; riboprina; 6-N-((3-Methyl-2-butenyl)amino)-9-b-D-ribofuranosyl-9H-purine; N6-isopentenyladenosine; 6-(γ,γ-Dimethylallylamino)purine riboside; riboprine; N6-ISOPENTENYLADENOSINE-D6; isopentenyladenosine; riboprinum; Isopentenyl-Adenosine; N(6)-(δ(2)-isopentenyl)adenosine; 2-IP RIBOSIDE; EINECS 231-771-3; N6-(D2-Isopentenyl)adenosine; N-6-(δ-2-Isopentenyl)adenosinehemihydrate; 2ipa; N(6)-(Delta(2)-isopentenyl)adenosine; n-isopentenyladenosine; MFCD00005741
Molecular FormulaC15H21O4N5
Molecular Weight335.36
Purity98.00
Density1.6±0.1 g/cm3
Boiling Point647.2±65.0 °C at 760 mmHg
Melting Point143-146°C
Storage Condition-20℃
ApplicationN6-isopentenyl adenosine (ribopurine), an RNA modification found in cytokinins that regulates plant growth/differentiation, and a subset of tRNAs that increase the efficiency and accuracy of translati
MDL NumberMFCD00005741
SMILESCC(C)=CCNc1ncnc2c1ncn2C1OC(CO)C(O)C1O
InChIInChI=1S/C15H21N5O4/c1-8(2)3-4-16-13-10-14(18-6-17-13)20(7-19-10)15-12(23)11(22)9(5-21)24-15/h3,6-7,9,11-12,15,21-23H,4-5H2,1-2H3,(H,16,17,18)/t9-,11-,12-,15-/m1/s1
InChI KeyUSVMJSALORZVDV-SDBHATRESA-N
Hazard Symbolstransportation
MSDSmsds/33953_1_7724_76_7.pdf
BioactivityN6-Isopentenyladenosine (Riboprine), an RNA modification found in cytokinins, which regulate plant growth/differentiation, and a subset of tRNAs, where it improves the efficiency and accuracy of translation. N6-Isopentenyladenosine, an end product of the mevalonate pathway, is an autophagy inhibitor with an interesting anti-melanoma activity[1][2][3]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Autophagy >> Autophagy In Vitro N6-isopentenyladenosine dual targeting of AMPK and Rab7 prenylation inhibits melanoma growth through the impairment of autophagic flux[2]. References [1]. Colombo F, et al. Pharmacogenomics and analogues of the antitumour agent N6-isopentenyladenosine. Int J Cancer. 2009;124(9):2179-2185. [2]. Ranieri R, et al. N6-isopentenyladenosine dual targeting of AMPK and Rab7 prenylation inhibits melanoma growth through the impairment of autophagic flux. Cell Death Differ. 2018;25(2):353-367. [3]. Cheng HP, et al. Chemical Deprenylation of N6 -Isopentenyladenosine (i6 A) RNA. Angew Chem Int Ed Engl. 2020;59(26):10645-10650. Chemical & Physical Properties Density 1.6±0.1 g/cm3 Boiling Point 647.2±65.0 °C at 760 mmHg Melting Point 143-146°C Molecular Formula C15H21N5O4 Molecular Weight 335.358 Flash Point 345.2±34.3 °C Exact Mass 335.159363 PSA 125.55000 LogP 1.31 Vapour Pressure 0.0±2.0 mmHg at 25°C Index of Refraction 1.708 InChIKey USVMJSALORZVDV-SDBHATRESA-N SMILES CC(C)=CCNc1ncnc2c1ncn2C1OC(CO)C(O)C1O Storage condition −20°C
Use ofN6-Isopentenyladenosine (Riboprine), an RNA modification found in cytokinins, which regulate plant growth/differentiation, and a subset of tRNAs, where it improves the efficiency and accuracy of translation. N6-Isopentenyladenosine, an end product of the mevalonate pathway, is an autophagy inhibitor with an interesting anti-melanoma activity[1][2][3]. Properties Name N6-(Δ2-isopentenyl)adenosine Synonym More Synonyms N6-Isopentenyladenosine Biological Activity Description N6-Isopentenyladenosine (Riboprine), an RNA modification found in cytokinins, which regulate plant growth/differentiation, and a subset of tRNAs, where it improves the efficiency and accuracy of translation. N6-Isopentenyladenosine, an end product of the mevalonate pathway, is an autophagy inhibitor with an interesting anti-melanoma activity[1][2][3]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Autophagy >> Autophagy In Vitro N6-isopentenyladenosine dual targeting of AMPK and Rab7 prenylation inhibits melanoma growth through the impairment of autophagic flux[2]. References [1]. Colombo F, et al. Pharmacogenomics and analogues of the antitumour agent N6-isopentenyladenosine. Int J Cancer. 2009;124(9):2179-2185. [2]. Ranieri R, et al. N6-isopentenyladenosine dual targeting of AMPK and Rab7 prenylation inhibits melanoma growth through the impairment of autophagic flux. Cell Death Differ. 2018;25(2):353-367. [3]. Cheng HP, et al. Chemical Deprenylation of N6 -Isopentenyladenosine (i6 A) RNA. Angew Chem Int Ed Engl. 2020;59(26):10645-10650. Chemical & Physical Properties Molecular Formula C15H21N5O4 Exact Mass 335.159363 PSA 125.55000 Index of Refraction 1.708 InChIKey USVMJSALORZVDV-SDBHATRESA-N
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available See reverse side of invoice or packing slip.
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