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4-Nitrophenyl alpha-D-galactopyranoside

Name: 4-Nitrophenyl alpha-D-galactopyranoside
Brand: 2A Biotech
SKU: 2A-9033749

CAS Number7493-95-0

Synonyms4-nitrophenyl-alpha-D-galactoside; MFCD00065050; EINECS 231-343-6

Molecular FormulaC12H15NO8

Molecular Weight301.25

Purity≥99 (TLC)%

Density1.6±0.1 g/cm3

Boiling Point582.2±50.0 °C at 760 mmHg

Melting Point166-169ºC

Appearancepowder

EINECS231-343-6

MSDSChinese English

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Signal WordWarning

Cat. No.: 2A-9033749 Purity: ≥99 (TLC)%

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Quality Control of [ 7493-95-0 ] Purity: ≥99 (TLC)% SDS Specification MoL

Chemical & Physical Properties
CAS Number	7493-95-0
Catalog No.	2A-9033749
Chinese Name	4-硝基苯-α-D-吡喃半乳糖苷
Synonyms	4-nitrophenyl-alpha-D-galactoside; MFCD00065050; EINECS 231-343-6
Molecular Formula	C12H15NO8
Molecular Weight	301.25
Purity	≥99 (TLC)
Density	1.6±0.1 g/cm3
Boiling Point	582.2±50.0 °C at 760 mmHg
Melting Point	166-169ºC
Appearance	powder
Storage Condition	Sealed in a cool, dry environment at 2-8ºC
Application	4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) is an artificial substrate of 4-nitrophenyl (pNP) glycopyranoside for the detection of α-galactosidase activity. When 4-Nitrophenyl α-D-galactopyr
EINECS	231-343-6
PubChem ID	24897448
MDL Number	MFCD00065050
SMILES	OC[C@H]1O[C@H](Oc2ccc(cc2)[N+]([O-])=O)[C@H](O)[C@@H](O)[C@H]1O
InChI	1S/C12H15NO8/c14-5-8-9(15)10(16)11(17)12(21-8)20-7-3-1-6(2-4-7)13(18)19/h1-4,8-12,14-17H,5H2/t8-,9+,10+,11-,12+/m1/s1
InChI Key	IFBHRQDFSNCLOZ-IIRVCBMXSA-N
Beilstein/REAXYS	92214
NACRES Code	NA.32
UNSPSC	12352204
Hazard Symbols	transportation
MSDS	msds/33749_1_7493_95_0.pdf
Bioactivity	4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) is an artificial substrate of 4-nitrophenyl (pNP) glycopyranoside for detecting α-galactosidase activity. The amount of released pNP is significantly increased when 4-Nitrophenyl α-D-galactopyranoside is used as substrates[1]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others In Vitro Using 4-nitorophenol (pNP)-glycopyranosides as pseudosubstrates, the amount of liberated pNP from the 4-Nitrophenyl α-D-galactopyranoside is significantly higher than that from the other pNP-glycopyranosides at pH 4.0 whereas no activity was detected at pH 7.0[1]. The digestion assays using 4-nitrophenyl (pNP) glycopyranosides as artificial substrates shows that yieldin liberated galactose residues from 4-Nitrophenyl α-D-galactopyranoside mainly at pH 4.0, i.e. the pH level where yield threshold is decreased at most[1]. References [1]. Okamoto-Nakazato A. Implications of the galactosidase activity of yieldin in the regulatory mechanism of yield threshold that is fundamental to cell wall extension. Physiol Plant. 2018 Jun;163(2):259-266. Chemical & Physical Properties Density 1.6±0.1 g/cm3 Boiling Point 582.2±50.0 °C at 760 mmHg Melting Point 166-169ºC Molecular Formula C12H15NO8 Molecular Weight 301.249 Flash Point 305.9±30.1 °C Exact Mass 301.079773 PSA 145.20000 LogP -0.55 Vapour Pressure 0.0±1.7 mmHg at 25°C Index of Refraction 1.648 InChIKey IFBHRQDFSNCLOZ-IIRVCBMXSA-N SMILES O=[N+]([O-])c1ccc(OC2OC(CO)C(O)C(O)C2O)cc1 Storage condition 2-8°C
Use of	4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) is an artificial substrate of 4-nitrophenyl (pNP) glycopyranoside for detecting α-galactosidase activity. The amount of released pNP is significantly increased when 4-Nitrophenyl α-D-galactopyranoside is used as substrates[1]. Properties Articles28 Name 4-nitrophenyl-α-D-galactoside Synonym More Synonyms 4-Nitrophenyl α-D-galactopyranoside Biological Activity Description 4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) is an artificial substrate of 4-nitrophenyl (pNP) glycopyranoside for detecting α-galactosidase activity. The amount of released pNP is significantly increased when 4-Nitrophenyl α-D-galactopyranoside is used as substrates[1]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others In Vitro Using 4-nitorophenol (pNP)-glycopyranosides as pseudosubstrates, the amount of liberated pNP from the 4-Nitrophenyl α-D-galactopyranoside is significantly higher than that from the other pNP-glycopyranosides at pH 4.0 whereas no activity was detected at pH 7.0[1]. The digestion assays using 4-nitrophenyl (pNP) glycopyranosides as artificial substrates shows that yieldin liberated galactose residues from 4-Nitrophenyl α-D-galactopyranoside mainly at pH 4.0, i.e. the pH level where yield threshold is decreased at most[1]. References [1]. Okamoto-Nakazato A. Implications of the galactosidase activity of yieldin in the regulatory mechanism of yield threshold that is fundamental to cell wall extension. Physiol Plant. 2018 Jun;163(2):259-266. Chemical & Physical Properties Molecular Formula C12H15NO8 Exact Mass 301.079773 PSA 145.20000 LogP -0.55 Index of Refraction 1.648 InChIKey IFBHRQDFSNCLOZ-IIRVCBMXSA-N
Transport Info	Product name: Purity: 98.0%
MSDS Transport Info	Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available

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4-Nitrophenyl alpha-D-galactopyranoside

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