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HEPES structure, CAS 7365-45-9

HEPES

CAS Number7365-45-9

Synonyms4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; hepesfreeacid; 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid; 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid; EIT hydrobromide; hepes solution; 4-(2-hydroxyethyl)-1-piperazineethanesulphonic acid; GOOD'S BUFFER; HEPES; HEPES BUFFER PH 8.0; 2-[4-(2-Hydroxyethyl)-1-piperazinyl]ethanesulfonic acid; EINECS 230-907-9; MFCD00006158

Molecular FormulaC8H18N2O4S

Molecular Weight238.30

Purity≥99.5 (titration)%

Density1.3±0.1 g/cm3

Boiling Point

Melting Point234-238 °C

Flash Point

Appearancecrystalline powder

EINECS230-907-9

MSDSChineseEnglish

Symbol

Signal Word

Cat. No.: 2A-0201359 Purity: ≥99.5 (titration)%
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Quality Control of [ 7365-45-9 ] Purity: ≥99.5 (titration)% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number7365-45-9
Catalog No.2A-0201359
Chinese Name4-羟乙基哌嗪乙磺酸
Synonyms4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; hepesfreeacid; 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid; 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid; EIT hydrobromide; hepes solution; 4-(2-hydroxyethyl)-1-piperazineethanesulphonic acid; GOOD'S BUFFER; HEPES; HEPES BUFFER PH 8.0; 2-[4-(2-Hydroxyethyl)-1-piperazinyl]ethanesulfonic acid; EINECS 230-907-9; MFCD00006158
Molecular FormulaC8H18N2O4S
Molecular Weight238.30
Purity≥99.5 (titration)
Density1.3±0.1 g/cm3
Melting Point234-238 °C
Appearancecrystalline powder
Water SolubilitySoluble
Storage ConditionSealed in a cool, dry environment at 2-8ºC.
ApplicationHEPES is a zwitterionic chemical buffer widely used in cell culture. HEPES is an effective buffer at pH 6.8 to 8.2. HEPES is a potent inducer of lysosomal biogenesis.
EINECS230-907-9
HTC29335995
PubChem ID24895572
MDL NumberMFCD00006158
SMILESOCCN1CCN(CC1)CCS(O)(=O)=O
InChI1S/C8H18N2O4S/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14/h11H,1-8H2,(H,12,13,14)
InChI KeyJKMHFZQWWAIEOD-UHFFFAOYSA-N
Beilstein/REAXYS883043
NACRES CodeNA.25
UNSPSC12161700
MSDSmsds/33591_1_7365_45_9.pdf
Use ofHEPES, a zwitterionic chemical buffering agent, is broadly applied in cell culture. HEPES is effective at pH 6.8 to 8.2. HEPES is a potent inducer of lysosome biogenesis[1][2][3]. Properties Articles4172 Name 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid Synonym More Synonyms HEPES Biological Activity Description HEPES, a zwitterionic chemical buffering agent, is broadly applied in cell culture. HEPES is effective at pH 6.8 to 8.2. HEPES is a potent inducer of lysosome biogenesis[1][2][3]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. Suzuki T, et al. Nonvolatile buffer coating of titanium to prevent its biological aging and for drug delivery. Biomaterials. 2010;31(18):4818-4828. [2]. Sledź P, et al. An experimental charge density of HEPES. Acta Crystallogr B. 2010;66(Pt 4):482-492. [3]. Tol MJ, et al. HEPES activates a MiT/TFE-dependent lysosomal-autophagic gene network in cultured cells: A call for caution. Autophagy. 2018;14(3):437-449. Chemical & Physical Properties Molecular Formula C8H18N2O4S Exact Mass 238.098724 PSA 89.46000 LogP -2.67 Index of Refraction 1.543 InChIKey JKMHFZQWWAIEOD-UHFFFAOYSA-N Stability Stable. Combustible. Incompatible with strong oxidizing agents. Protect from moisture. Water Solubility Soluble Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : 1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)- CAS REGISTRY NUMBER : BEILSTEIN REFERENCE NO. : LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : C8-H18-N2-O4-S HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Bird - quail DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EESADV Ecotoxicology and Environmental Safety. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1977- Volume(issue)/page/year: 6,149,1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9468 No. of Facilities: 239 (estimated) No. of Industries: 2 No. of Occupations: 7 No. of Employees: 3025 (estimated) No. of Female Employees: 2233 (estimated) Safety Information Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter Hazard Codes Xi: Irritant; RIDADR NONH for all modes of transport WGK Germany 1 RTECS TL6809000 HS Code 29335995
Transport InfoProduct name: N-(2-hydroxyethyl)piperazine-N'-2-ethanesulfonic acid
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