CAS Number6472-91-9
SynonymsC.I.Direct Yellow 1; Chrysamin-G; CHRYSAMINE; 6,6'-dihydroxy-3,3'-biphenyl-4,4'-diyl-bis-azo-dibenzoic acid disodium salt; 6,6'-Dihydroxy-3,3'-biphenyl-4,4'-diylbisazo-di-benzoesaeure,Dinatrium-Salz
Molecular FormulaC26H16N4Na2O6
Molecular Weight526.41
Purity≥95 (HPLC)%
Boiling Point711.3ºC at 760 mmHg
Appearancesolid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 6472-91-9 |
| Catalog No. | 2A-9032923 |
| Chinese Name | N-芴甲氧羰基-D-1,2,3,4-四氢异喹啉-3-羧酸 |
| Synonyms | C.I.Direct Yellow 1; Chrysamin-G; CHRYSAMINE; 6,6'-dihydroxy-3,3'-biphenyl-4,4'-diyl-bis-azo-dibenzoic acid disodium salt; 6,6'-Dihydroxy-3,3'-biphenyl-4,4'-diylbisazo-di-benzoesaeure,Dinatrium-Salz |
| Molecular Formula | C26H16N4Na2O6 |
| Molecular Weight | 526.41 |
| Purity | ≥95 (HPLC) |
| Boiling Point | 711.3ºC at 760 mmHg |
| Appearance | solid |
| Storage Condition | -20°C, sealed, dry |
| Application | Chrysame G is a carboxylic acid analogue of Congo red that can be used as a probe for amyloid deposition in Alzheimer's disease. Chrysalis G can also inhibit Aβ-induced PC12 cytotoxicity [1][2]. |
| PubChem ID | 24724433 |
| MDL Number | MFCD00045823 |
| SMILES | [Na+].[Na+].Oc1ccc(cc1C([O-])=O)N=Nc2ccc(cc2)-c3ccc(cc3)N=Nc4ccc(O)c(c4)C([O-])=O |
| InChI | 1S/C26H18N4O6.2Na/c31-23-11-9-19(13-21(23)25(33)34)29-27-17-5-1-15(2-6-17)16-3-7-18(8-4-16)28-30-20-10-12-24(32)22(14-20)26(35)36;;/h1-14,31-32H,(H,33,34)(H,35,36);;/q;2*+1/p-2 |
| InChI Key | AZOPGDOIOXKJRA-UHFFFAOYSA-L |
| NACRES Code | NA.77 |
| UNSPSC | 12352116 |
| Hazard Symbols | transportation |
| MSDS | msds/32923_1_6472_91_9.pdf |
| Bioactivity | Chrysamine G, a carboxylic acid analogue of Congo Red, can be used as a probe of amyloid deposition in Alzheimer's disease. Chrysamine G also can inhibit Aβ-induced toxicity in PC12 cells[1][2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease References [1]. Klunk WE, et, al. Chrysamine-G binding to Alzheimer and control brain: autopsy study of a new amyloid probe. Neurobiol Aging. Jul-Aug 1995;16(4):541-8. [2]. Klunk WE, et, al. Chrysamine-G, a lipophilic analogue of Congo red, inhibits A beta-induced toxicity in PC12 cells. Life Sci. 1998;63(20):1807-14. Chemical & Physical Properties Boiling Point 711.3ºC at 760 mmHg Molecular Formula C26H16N4Na2O6 Molecular Weight 526.40800 Flash Point 384ºC Exact Mass 526.08700 PSA 170.16000 LogP 4.32260 |
| Use of | Properties Articles11 Name chrysamine g Synonym More Synonyms CHRYSAMINE G Biological Activity Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease References [1]. Klunk WE, et, al. Chrysamine-G binding to Alzheimer and control brain: autopsy study of a new amyloid probe. Neurobiol Aging. Jul-Aug 1995;16(4):541-8. Chemical & Physical Properties Molecular Formula C26H16N4Na2O6 Exact Mass 526.08700 PSA 170.16000 LogP 4.32260 |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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