
CAS Number6104-58-1
SynonymsCBB G-250; Coomassie Brilliant Blue G250; EINECS 228-058-4; Cyanine G; PAGE BLUE G90; coomassie briliant blue G-250; coomassie blue G-250; Coomassie Brilliant blue; Polar Blue G; Blue G 250; BRILLIANT BLUE; coomassie brillant blue G; SERVA BLUE G; MFCD00078482
Molecular FormulaC47H48N3NaO7S2
Molecular Weight854.02
Purity98.00%
Density>1.0 g/cm3 (20ºC)
Melting Point100 °C
AppearanceDark blue-violet-brown crystalline powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 6104-58-1 |
| Catalog No. | 2A-9032480 |
| Chinese Name | 考马斯亮蓝G250 |
| Synonyms | CBB G-250; Coomassie Brilliant Blue G250; EINECS 228-058-4; Cyanine G; PAGE BLUE G90; coomassie briliant blue G-250; coomassie blue G-250; Coomassie Brilliant blue; Polar Blue G; Blue G 250; BRILLIANT BLUE; coomassie brillant blue G; SERVA BLUE G; MFCD00078482 |
| Molecular Formula | C47H48N3NaO7S2 |
| Molecular Weight | 854.02 |
| Purity | 98.00 |
| Density | >1.0 g/cm3 (20ºC) |
| Melting Point | 100 °C |
| Appearance | Dark blue-violet-brown crystalline powder |
| Storage Condition | This product should be kept sealed. |
| Application | Brilliant Blue G-250 is a dye commonly used for visualizing proteins separated by SDS-PAGE. The staining process is simple and the quantification is high. In the Bradford Protein Assay, protein concen |
| HTC | 32041200 |
| MDL Number | MFCD00078482 |
| SMILES | [Na+].[S](=O)(=O)([O-])c1cc(ccc1)CN(CC)c2cc(c(cc2)[C+](c5c(cc(cc5)N(CC)Cc6cc(ccc6)[S](=O)(=O)[O-])C)c3ccc(cc3)Nc4ccc(cc4)OCC)C |
| InChI | 1S/C47H49N3O7S2.Na/c1-6-49(31-35-11-9-13-43(29-35)58(51,52)53)40-21-25-45(33(4)27-40)47(37-15-17-38(18-16-37)48-39-19-23-42(24-20-39)57-8-3)46-26-22-41(28-34(46)5)50(7-2)32-36-12-10-14-44(30-36)59(54,55)56;/h9-30,48H,6-8,31-32H2,1-5H3,(H-,51,52,53,54,55,56);/q;+1/p-1 |
| InChI Key | CMGWKYXJIYYESN-UHFFFAOYSA-M |
| NACRES Code | NC.01 |
| UNSPSC | 41105305 |
| Hazard Symbols | transportation |
| MSDS | msds/32480_1_6104_58_1.pdf |
| Bioactivity | Brilliant Blue G-250 is a dye commonly used for the visualization of proteins separated by SDS-PAGE, offering a simple staining procedure and high quantitation. In the Bradford protein assay, protein concentrations are determined by the absorbance at 595 nm due to the binding of Brilliant Blue G-250 to proteins. Brilliant Blue G-250 is a safe highly selective P2×7R antagonist with promising consequent inactivation of NLRP3 inflammasome[1][2][3]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. Dyballa N, Metzger S. Fast and sensitive colloidal coomassie G-250 staining for proteins in polyacrylamide gels. J Vis Exp. 2009;(30):1431. Published 2009 Aug 3. [2]. Han XX, et al. Highly sensitive protein concentration assay over a wide range via surface-enhanced Raman scattering of Coomassie brilliant blue. Anal Chem. 2010;82(11):4325-4328. [3]. Zohny MH, et al. Coomassie brilliant blue G-250 dye attenuates bleomycin-induced lung fibrosis by regulating the NF-κB and NLRP3 crosstalk: A novel approach for filling an unmet medical need [published online ahead of print, 2022 Feb 21]. Biomed Pharmacother. 2022;148:112723. Chemical & Physical Properties Density >1.0 g/cm3 (20ºC) Melting Point 100 °C Molecular Formula C47H48N3NaO7S2 Molecular Weight 854.020 Flash Point 11 °C Exact Mass 853.283142 PSA 158.67000 LogP 11.19820 InChIKey RWVGQQGBQSJDQV-UHFFFAOYSA-M SMILES CCOc1ccc(Nc2ccc(C(=C3C=CC(=[N+](CC)Cc4cccc(S(=O)(=O)[O-])c4)C=C3C)c3ccc(N(CC)Cc4cccc(S(=O)(=O)[O-])c4)cc3C)cc2)cc1.[Na+] Storage condition Store at RT. |
| Use of | Brilliant Blue G-250 is a dye commonly used for the visualization of proteins separated by SDS-PAGE, offering a simple staining procedure and high quantitation. In the Bradford protein assay, protein concentrations are determined by the absorbance at 595 nm due to the binding of Brilliant Blue G-250 to proteins. Brilliant Blue G-250 is a safe highly selective P2×7R antagonist with promising consequent inactivation of NLRP3 inflammasome[1][2][3]. Properties Articles51 Name Acid Blue 90 Synonym More Synonyms Brilliant blue G-250 Biological Activity Description Brilliant Blue G-250 is a dye commonly used for the visualization of proteins separated by SDS-PAGE, offering a simple staining procedure and high quantitation. In the Bradford protein assay, protein concentrations are determined by the absorbance at 595 nm due to the binding of Brilliant Blue G-250 to proteins. Brilliant Blue G-250 is a safe highly selective P2×7R antagonist with promising consequent inactivation of NLRP3 inflammasome[1][2][3]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. Dyballa N, Metzger S. Fast and sensitive colloidal coomassie G-250 staining for proteins in polyacrylamide gels. J Vis Exp. 2009;(30):1431. Published 2009 Aug 3. [2]. Han XX, et al. Highly sensitive protein concentration assay over a wide range via surface-enhanced Raman scattering of Coomassie brilliant blue. Anal Chem. 2010;82(11):4325-4328. Chemical & Physical Properties Molecular Formula C47H48N3NaO7S2 Exact Mass 853.283142 PSA 158.67000 LogP 11.19820 InChIKey RWVGQQGBQSJDQV-UHFFFAOYSA-M Storage condition Store at RT. |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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