
CAS Number6048-68-6
SynonymsNonaethylene Glycol Monomethyl Ether; O-methyl-nonaethyleneglycol; O-Methyl-nonaaethylenglykol; 3,6,9,12,15,18,21,24,27-Nonaoxaoctacosan-1-ol; 3,6,9,12,15,18,21,24,27-Nonaoxaoctacosanol; 2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-ol; O-methyl-nonaaethylene glycol; Nonaethylene glycol monomethyl ether; MPEG9-OH
Molecular FormulaC19H40O10
Molecular Weight428.52
Purity98.00%
Density1.1±0.1 g/cm3
Boiling Point490.1±40.0 °C at 760 mmHg
Melting Point14ºC
AppearanceClear liquid colorless - light yellow
EINECS6048-68-6
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 6048-68-6 |
| Catalog No. | 2A-9032433 |
| Chinese Name | 九甘醇单甲醚 |
| Synonyms | Nonaethylene Glycol Monomethyl Ether; O-methyl-nonaethyleneglycol; O-Methyl-nonaaethylenglykol; 3,6,9,12,15,18,21,24,27-Nonaoxaoctacosan-1-ol; 3,6,9,12,15,18,21,24,27-Nonaoxaoctacosanol; 2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-ol; O-methyl-nonaaethylene glycol; Nonaethylene glycol monomethyl ether; MPEG9-OH |
| Molecular Formula | C19H40O10 |
| Molecular Weight | 428.52 |
| Purity | 98.00 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 490.1±40.0 °C at 760 mmHg |
| Melting Point | 14ºC |
| Appearance | Clear liquid colorless - light yellow |
| Storage Condition | Avoid light, keep in a cool and dry place, sealed |
| Application | Nonaethylene glycol monomethyl ether is a PROTAC linker, belonging to the PEG class. Can be used to synthesize PROTAC molecules. |
| EINECS | 6048-68-6 |
| HTC | 2909440000 |
| MDL Number | MFCD06797148 |
| SMILES | COCCOCCOCCOCCOCCOCCOCCOCCOCCO |
| InChI Key | VVHAVLIDQNWEKF-UHFFFAOYSA-N |
| MSDS | msds/32433_1_6048_68_6.pdf |
| Bioactivity | Nonaethylene glycol monomethyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker Target PEGs In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 490.1±40.0 °C at 760 mmHg Melting Point 14ºC Molecular Formula C19H40O10 Molecular Weight 428.515 Flash Point 250.2±27.3 °C Exact Mass 428.262146 PSA 103.30000 LogP -3.66 Vapour Pressure 0.0±2.8 mmHg at 25°C Index of Refraction 1.453 InChIKey VVHAVLIDQNWEKF-UHFFFAOYSA-N SMILES COCCOCCOCCOCCOCCOCCOCCOCCOCCO Storage condition 2-8°C |
| Use of | Nonaethylene glycol monomethyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Properties Name 2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol Synonym More Synonyms Nonaethylene glycol monomethyl ether Biological Activity Description Nonaethylene glycol monomethyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 Chemical & Physical Properties Molecular Formula C19H40O10 Exact Mass 428.262146 PSA 103.30000 LogP -3.66 Index of Refraction 1.453 InChIKey VVHAVLIDQNWEKF-UHFFFAOYSA-N SMILES COCCOCCOCCOCCOCCOCCOCCOCCOCCO |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 5.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 0.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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