CAS Number6018-19-5
SynonymsSodium 4-Aminosalicylate; EINECS 205-091-2; 4-amino-2-hydroxybenzoic acid sodium salt dihydrate; Benzoic acid, 4-amino-2-hydroxy-, monosodium salt, dihydrate; Benzoic acid, 4-amino-2-hydroxy-, sodium salt, hydrate (1:1:2); 4-Aminosalicylic acid sodium salt dihydrate; AMINOSALICYLATE SODIUM,DIHYDRATE; 4-AMINOSALICYLIC ACID,NA SALT; Sodium 4-amino-2-hydroxybenzoate dihydrate; 4-AMINOSALICYLIC ACID SODIUM SALT 2-HYDRATE; 4-Amino-2-hydroxy-benzoesaeure,Natrium-Salz; 4-AMINOSALICYLIC ACID SODIUM DIHYDRATE; sodium p-aminosalicylate dihydrate; SODIUM AMINOSALICYLA; 4-amino-2-hydroxy-benzoic acid,sodium-salt; 4-amino-salicylic acid sodium salt; AMINOSALICYLATESODIUM,DIHYDRATE,USP; UNII-S38B9W6AXW; PAS-NA 2H2O; Sodium 4-aminosalicy; MFCD00151044; Sodium 4-amino-2-hydroxybenzoate hydrate (1:1:2)
Molecular FormulaC7H10NNaO5
Molecular Weight211.15
Purity98.00%
Boiling Point380.8ºC at 760 mmHg
Melting Point250 °C
AppearanceWhite to beige fine crystalline powder
EINECS205-091-2
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 6018-19-5 |
| Catalog No. | 2A-9032402 |
| Chinese Name | 对氨基水杨酸钠 |
| Synonyms | Sodium 4-Aminosalicylate; EINECS 205-091-2; 4-amino-2-hydroxybenzoic acid sodium salt dihydrate; Benzoic acid, 4-amino-2-hydroxy-, monosodium salt, dihydrate; Benzoic acid, 4-amino-2-hydroxy-, sodium salt, hydrate (1:1:2); 4-Aminosalicylic acid sodium salt dihydrate; AMINOSALICYLATE SODIUM,DIHYDRATE; 4-AMINOSALICYLIC ACID,NA SALT; Sodium 4-amino-2-hydroxybenzoate dihydrate; 4-AMINOSALICYLIC ACID SODIUM SALT 2-HYDRATE; 4-Amino-2-hydroxy-benzoesaeure,Natrium-Salz; 4-AMINOSALICYLIC ACID SODIUM DIHYDRATE; sodium p-aminosalicylate dihydrate; SODIUM AMINOSALICYLA; 4-amino-2-hydroxy-benzoic acid,sodium-salt; 4-amino-salicylic acid sodium salt; AMINOSALICYLATESODIUM,DIHYDRATE,USP; UNII-S38B9W6AXW; PAS-NA 2H2O; Sodium 4-aminosalicy; MFCD00151044; Sodium 4-amino-2-hydroxybenzoate hydrate (1:1:2) |
| Molecular Formula | C7H10NNaO5 |
| Molecular Weight | 211.15 |
| Purity | 98.00 |
| Boiling Point | 380.8ºC at 760 mmHg |
| Melting Point | 250 °C |
| Appearance | White to beige fine crystalline powder |
| Water Solubility | soluble |
| Storage Condition | Avoid light, keep in a cool and dry place, sealed |
| Application | Sodium 4-aminosalicylate dihydrate is a primary anti-TB compound. |
| EINECS | 205-091-2 |
| HTC | 2918219000 |
| MDL Number | MFCD00151044 |
| SMILES | O.O.[Na+].Nc1ccc(c(O)c1)C([O-])=O |
| InChI | 1S/C7H7NO3.Na.2H2O/c8-4-1-2-5(7(10)11)6(9)3-4;;;/h1-3,9H,8H2,(H,10,11);;2*1H2/q;+1;;/p-1 |
| InChI Key | GMUQJDAYXZXBOT-UHFFFAOYSA-M |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/32402_1_6018_19_5.pdf |
| Bioactivity | Sodium 4-aminosalicylate dihydrate is one of the antimycobacterial drugs currently used for multidrug-resistant tuberculosis. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. Zheng J, et al. para-Aminosalicylic acid is a prodrug targeting dihydrofolate reductase in Mycobacterium tuberculosis. J Biol Chem. 2013 Aug 9;288(32):23447-56. [2]. Sy SK, et al. N-acetyltransferase genotypes and the pharmacokinetics and tolerability of para-aminosalicylic acid in drug-resistant pulmonary tuberculosis patients. Antimicrob Agents Chemother. 2015 May 11. pii: AAC.04049-14. Chemical & Physical Properties Boiling Point 380.8ºC at 760 mmHg Melting Point 250 °C Molecular Formula C7H10NNaO5 Molecular Weight 211.148 Flash Point 184.1ºC Exact Mass 211.045670 PSA 104.84000 InChIKey GMUQJDAYXZXBOT-UHFFFAOYSA-M SMILES Nc1ccc(C(=O)[O-])c(O)c1.O.O.[Na+] Water Solubility soluble |
| Use of | Sodium 4-aminosalicylate dihydrate is one of the antimycobacterial drugs currently used for multidrug-resistant tuberculosis. Properties Articles26 Name Sodium 4-aminosalicylate dihydrate Synonym More Synonyms Sodium 4-aminosalicylate dihydrate Biological Activity Description Sodium 4-aminosalicylate dihydrate is one of the antimycobacterial drugs currently used for multidrug-resistant tuberculosis. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. Zheng J, et al. para-Aminosalicylic acid is a prodrug targeting dihydrofolate reductase in Mycobacterium tuberculosis. J Biol Chem. 2013 Aug 9;288(32):23447-56. [2]. Sy SK, et al. N-acetyltransferase genotypes and the pharmacokinetics and tolerability of para-aminosalicylic acid in drug-resistant pulmonary tuberculosis patients. Antimicrob Agents Chemother. 2015 May 11. pii: AAC.04049-14. Chemical & Physical Properties Molecular Formula C7H10NNaO5 Exact Mass 211.045670 PSA 104.84000 InChIKey GMUQJDAYXZXBOT-UHFFFAOYSA-M Water Solubility soluble |
| Tax Rebate | 13.0% |
| Supervision | A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Inspection | R. Hygiene supervision and inspection of imported food S. Hygiene supervision and inspection of exported food |
| Transport Info | Product name: Supervision conditions A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
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