CAS Number5625-37-6
SynonymsPiperazine-N,N'-bis (2-ethanesulfonic acid); 1,4-Piperazinediethanesulfonic acid, sodium salt (2:3); PIPES; 2,2'-Piperazine-1,4-diyldiethanesulfonic acid; 2,2'-(1,4-Piperazinediyl)diethanesulfonic acid; 1,4-Piperazine bis(ethanesulfonic acid); 1,4-Piperazinediethanesulfonic acid sesquisodium salt; Piperazine-N,N'-bis(2-ethanesulfonic acid); Piperazine-N,N′-bis(2-ethanesulfonic acid); Piperazine-1,4-bis(2-ethanesulfonic acid) sesquisodium salt; 1,4-Piperazinediethanesulfonic acid; MFCD00006159; EINECS 227-057-6; 2,2′-piperazine-1,4-diylbisethanesulfonic acid
Molecular FormulaC16H33N4Na3O12S4
Molecular Weight302.37
Purity≥99 (titration)%
Density1.5±0.1 g/cm3
Melting Point>300 °C (lit.)
Appearancecrystalline powder
EINECS227-057-6
Symbol
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| Chemical & Physical Properties | |
|---|---|
| CAS Number | 5625-37-6 |
| Catalog No. | 2A-9032023 |
| Chinese Name | 哌嗪-1,4-二乙磺酸 |
| Synonyms | Piperazine-N,N'-bis (2-ethanesulfonic acid); 1,4-Piperazinediethanesulfonic acid, sodium salt (2:3); PIPES; 2,2'-Piperazine-1,4-diyldiethanesulfonic acid; 2,2'-(1,4-Piperazinediyl)diethanesulfonic acid; 1,4-Piperazine bis(ethanesulfonic acid); 1,4-Piperazinediethanesulfonic acid sesquisodium salt; Piperazine-N,N'-bis(2-ethanesulfonic acid); Piperazine-N,N′-bis(2-ethanesulfonic acid); Piperazine-1,4-bis(2-ethanesulfonic acid) sesquisodium salt; 1,4-Piperazinediethanesulfonic acid; MFCD00006159; EINECS 227-057-6; 2,2′-piperazine-1,4-diylbisethanesulfonic acid |
| Molecular Formula | C16H33N4Na3O12S4 |
| Molecular Weight | 302.37 |
| Purity | ≥99 (titration) |
| Density | 1.5±0.1 g/cm3 |
| Melting Point | >300 °C (lit.) |
| Appearance | crystalline powder |
| Water Solubility | 0.1 M NaOH: 0.25 g/mL, clear, colorless |
| Storage Condition | Store in a cool, dry place, sealed |
| Application | PIPES (1,4-Piperazinediethanesulfonic acid) is an important component of PIPES buffer and is commonly used as biochemical reagents. |
| EINECS | 227-057-6 |
| HTC | 29335995 |
| PubChem ID | 24898793 |
| MDL Number | MFCD00006159 |
| SMILES | OS(=O)(=O)CCN1CCN(CC1)CCS(O)(=O)=O |
| InChI | 1S/C8H18N2O6S2/c11-17(12,13)7-5-9-1-2-10(4-3-9)6-8-18(14,15)16/h1-8H2,(H,11,12,13)(H,14,15,16) |
| InChI Key | IHPYMWDTONKSCO-UHFFFAOYSA-N |
| Beilstein/REAXYS | 817713 |
| NACRES Code | NA.25 |
| UNSPSC | 12161700 |
| Hazard Symbols | transportation |
| MSDS | msds/32023_1_5625_37_6.pdf |
| Bioactivity | PIPES (1,4-Piperazinediethanesulfonic acid) is an important component of PIPES buffer agent used in biochemistry[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology In Vitro To prepare the pH PIPES buffer, 173 g of 1,4-piperazinediethanesulfonic acid are dissolved into 1 L of deionized water. The pH of the PIPES buffer is adjusted to 6.8 by adding pellets of sodium hydroxide. PIPES buffer can be used to PIPES buffer, it can prevent the glutaraldehyde fixation induced lipid loss and artifacts[1]. References [1]. Jason Moggridge, et al. Sensitive Detection of Immunoglobulin G Stability Using in Real-Time Isothermal Differential Scanning Fluorimetry: Determinants of Protein Stability for Antibody-Based Therapeutics. Technol Cancer Res Treat. 2017 Dec;16(6):997-1005. Chemical & Physical Properties Density 1.5±0.1 g/cm3 Melting Point >300 °C(lit.) Molecular Formula C16H33N4Na3O12S4 Molecular Weight 670.682 Exact Mass 670.067078 PSA 131.98000 LogP -4.21 Index of Refraction 1.566 InChIKey IHPYMWDTONKSCO-UHFFFAOYSA-N SMILES O=S(=O)(O)CCN1CCN(CCS(=O)(=O)O)CC1 Storage condition Store at RT. Water Solubility 0.1 M NaOH: 0.25 g/mL, clear, colorless |
| Use of | PIPES (1,4-Piperazinediethanesulfonic acid) is an important component of PIPES buffer agent used in biochemistry[1]. Properties Articles156 Name 2,2'-piperazine-1,4-diylbisethanesulfonic acid Synonym More Synonyms PIPES Biological Activity Description PIPES (1,4-Piperazinediethanesulfonic acid) is an important component of PIPES buffer agent used in biochemistry[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology References [1]. Jason Moggridge, et al. Sensitive Detection of Immunoglobulin G Stability Using in Real-Time Isothermal Differential Scanning Fluorimetry: Determinants of Protein Stability for Antibody-Based Therapeutics. Technol Cancer Res Treat. 2017 Dec;16(6):997-1005. Chemical & Physical Properties Molecular Formula C16H33N4Na3O12S4 Exact Mass 670.067078 PSA 131.98000 LogP -4.21 Index of Refraction 1.566 InChIKey IHPYMWDTONKSCO-UHFFFAOYSA-N Storage condition Store at RT. |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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