CAS Number5399-87-1
Synonyms6-Chloronebularine; 6-CHLOROINOSINE; 6-Chloropurine riboside; 6-Chloropurine ribos; (2R,3R,4S,5R)-2-(6-Chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydro-3,4-furandiol; 6-Choropurine Riboside; 6-Chloropurineriboside; 6-Chloropurine-9-Beta-D-ribofuranoside; EINECS 217-904-8; (2R,3R,4S,5R)-2-(6-Chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 2',3',5'-tri-O-acetyl-6-chloro adenosine; 6-Chlorpurinribosid; 6-CLPR; 6-Chloro-9-(β-D-ribofuranosyl)-9H-purine; 6-Chloro-9-(β-D-ribofuranosyl)purine; MFCD00005738; 6-Chloro-6-deoxyinosine; 6-CHLOROPURINE NUCLEOSIDE; 6-Chlrorpurine riboside; 6-Cl-riboside; 6-deamino-6-chloroadenosine; 6-Chloro-9-b-D-ribofuranosyl-9H-purine; 6-Chloropurine-9-β-D-ribofuranoside; 6-chloro-9-pentofuranosylpurine; 6-Chloropurinosine; 6-Chloropurine ribose; 6-C
Molecular FormulaC10H11ClN4O4
Molecular Weight286.67
Purity99%
Density2.0±0.1 g/cm3
Boiling Point614.8±65.0 °C at 760 mmHg
Melting Point158-162 °C (dec.) (lit.)
Appearancepowder
EINECS226-438-4
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 5399-87-1 |
| Catalog No. | 2A-9031757 |
| Chinese Name | 6-氯嘌呤核苷 |
| Synonyms | 6-Chloronebularine; 6-CHLOROINOSINE; 6-Chloropurine riboside; 6-Chloropurine ribos; (2R,3R,4S,5R)-2-(6-Chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydro-3,4-furandiol; 6-Choropurine Riboside; 6-Chloropurineriboside; 6-Chloropurine-9-Beta-D-ribofuranoside; EINECS 217-904-8; (2R,3R,4S,5R)-2-(6-Chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 2',3',5'-tri-O-acetyl-6-chloro adenosine; 6-Chlorpurinribosid; 6-CLPR; 6-Chloro-9-(β-D-ribofuranosyl)-9H-purine; 6-Chloro-9-(β-D-ribofuranosyl)purine; MFCD00005738; 6-Chloro-6-deoxyinosine; 6-CHLOROPURINE NUCLEOSIDE; 6-Chlrorpurine riboside; 6-Cl-riboside; 6-deamino-6-chloroadenosine; 6-Chloro-9-b-D-ribofuranosyl-9H-purine; 6-Chloropurine-9-β-D-ribofuranoside; 6-chloro-9-pentofuranosylpurine; 6-Chloropurinosine; 6-Chloropurine ribose; 6-C |
| Molecular Formula | C10H11ClN4O4 |
| Molecular Weight | 286.67 |
| Purity | 99 |
| Density | 2.0±0.1 g/cm3 |
| Boiling Point | 614.8±65.0 °C at 760 mmHg |
| Melting Point | 158-162 °C (dec.) (lit.) |
| Appearance | powder |
| Storage Condition | 2-8°C |
| Application | Chloropurine nucleosides are purine nucleoside analogs. Purine nucleoside analogues have broad antitumor activity and target indolent lymphoid malignancies. The anti-cancer mechanism in this process r |
| EINECS | 226-438-4 |
| HTC | 2942000000 |
| PubChem ID | 24888323 |
| MDL Number | MFCD00005738 |
| SMILES | OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(Cl)ncnc23 |
| InChI | 1S/C10H11ClN4O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2/t4-,6-,7-,10-/m1/s1 |
| InChI Key | XHRJGHCQQPETRH-KQYNXXCUSA-N |
| Beilstein/REAXYS | 40573 |
| NACRES Code | NA.22 |
| UNSPSC | 12352123 |
| MSDS | msds/31757_1_5399_87_1.pdf |
| Bioactivity | Chloropurine riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog References [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. Chemical & Physical Properties Density 2.0±0.1 g/cm3 Boiling Point 614.8±65.0 °C at 760 mmHg Melting Point 161-163ºC (dec.) Molecular Formula C10H11ClN4O4 Molecular Weight 286.67 Flash Point 325.6±34.3 °C Exact Mass 286.046875 PSA 113.52000 LogP -0.56 Vapour Pressure 0.0±1.9 mmHg at 25°C Index of Refraction 1.846 InChIKey XHRJGHCQQPETRH-KQYNXXCUSA-N SMILES OCC1OC(n2cnc3c(Cl)ncnc32)C(O)C1O Storage condition 2-8°C |
| Use of | Chloropurine riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Properties Articles15 Name 6-Chloropurine riboside Synonym More Synonyms 6-Chloropurineriboside Biological Activity Description Chloropurine riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog References [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. Chemical & Physical Properties Exact Mass 286.046875 PSA 113.52000 LogP -0.56 Index of Refraction 1.846 InChIKey XHRJGHCQQPETRH-KQYNXXCUSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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