CAS Number5106-98-9
Synonyms4-Chloro Salicylic Acid; 4-Chloro-2-Hydroxy Benzoic Acid; MFCD00002449; 4-Chlorosalicylic Acid; 4-Chloro-2-hydroxybenzoic acid; EINECS 225-829-7
Molecular FormulaC7H5ClO3
Molecular Weight172.566
Purity98.00%
Density1.5±0.1 g/cm3
Boiling Point321.1±27.0 °C at 760 mmHg
Melting Point210-212 °C(lit.)
AppearanceOff-white to light beige powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 5106-98-9 |
| Catalog No. | 2A-9031447 |
| Chinese Name | 4-氯水杨酸 |
| Synonyms | 4-Chloro Salicylic Acid; 4-Chloro-2-Hydroxy Benzoic Acid; MFCD00002449; 4-Chlorosalicylic Acid; 4-Chloro-2-hydroxybenzoic acid; EINECS 225-829-7 |
| Molecular Formula | C7H5ClO3 |
| Molecular Weight | 172.566 |
| Purity | 98.00 |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 321.1±27.0 °C at 760 mmHg |
| Melting Point | 210-212 °C(lit.) |
| Appearance | Off-white to light beige powder |
| Water Solubility | slightly soluble |
| Storage Condition | Avoid light, keep in a cool and dry place, sealed |
| Application | 4-Chlorosalicylic acid is a pharmaceutical intermediate. Inhibiting monophenolase and diphenolase activities, the IC50 values are 1.89 mM and 1.10 mM respectively. Has effective antibacterial activi |
| HTC | 2918219000 |
| SMILES | O=C(O)c1ccc(Cl)cc1O |
| InChI | InChI=1S/C7H5ClO3/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3,9H,(H,10,11) |
| InChI Key | LWXFCZXRFBUOOR-UHFFFAOYSA-N |
| Hazard Symbols | transportation |
| MSDS | msds/31447_2_5106_98_9.pdf |
| Bioactivity | 4-Chlorosalicylic acid is a pharmaceutical intermediate. Inhibits monophenolase and diphenolase activity with IC50s of 1.89 mM and 1.10 mM. Potent antimicrobial activity. Against E. coli with the MIC of 250 μg/mL and with the MBC of 500 μg/mL. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Signaling Pathways >> Anti-infection >> Fungal Natural Products >> Acids and Aldehydes Research Areas >> Infection Target IC50: 1.89 mM (monophenolase), 1.10 mM (diphenolase)[1] In Vitro 4-chlorosalicylic acid could inhibit both the diphenolase activity and the monophenolase activity of mushroom tyrosinase. 4-chlorosalicylic acid has broad-spectrum antimicrobial activity which could inhibits Gram-positive and Gram-negative bacteria and fungi[1]. References [1]. Han P, et al. Inhibitory effects of 4-chlorosalicylic acid on mushroom tyrosinase and its antimicrobial activities. 107 (2), 797-803, 2008 Chemical & Physical Properties Density 1.5±0.1 g/cm3 Boiling Point 321.1±27.0 °C at 760 mmHg Melting Point 210-212 °C(lit.) Molecular Formula C7H5ClO3 Molecular Weight 172.566 Flash Point 148.0±23.7 °C Exact Mass 171.992722 PSA 57.53000 LogP 3.14 Vapour Pressure 0.0±0.7 mmHg at 25°C Index of Refraction 1.630 InChIKey LWXFCZXRFBUOOR-UHFFFAOYSA-N SMILES O=C(O)c1ccc(Cl)cc1O Water Solubility slightly soluble |
| Use of | Properties Name 4-Chlorosalicylic acid Synonym More Synonyms 4-Chlorosalicylic acid Biological Activity Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Signaling Pathways >> Anti-infection >> Fungal Natural Products >> Acids and Aldehydes Research Areas >> Infection In Vitro 4-chlorosalicylic acid could inhibit both the diphenolase activity and the monophenolase activity of mushroom tyrosinase. 4-chlorosalicylic acid has broad-spectrum antimicrobial activity which could inhibits Gram-positive and Gram-negative bacteria and fungi[1]. References [1]. Han P, et al. Inhibitory effects of 4-chlorosalicylic acid on mushroom tyrosinase and its antimicrobial activities. 107 (2), 797-803, 2008 Chemical & Physical Properties Exact Mass 171.992722 PSA 57.53000 Index of Refraction 1.630 InChIKey LWXFCZXRFBUOOR-UHFFFAOYSA-N Water Solubility slightly soluble |
| Tax Rebate | 9.0% |
| Supervision | A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Inspection | R. Hygiene supervision and inspection of imported food S. Hygiene supervision and inspection of exported food |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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