CAS Number4792-15-8
SynonymsPentaethylene Glycol; 3,6,9,12-Tetraoxatetradecane-1,14-diol,Pentaglycol; MFCD00002878; EINECS 225-341-4; pentaethyleneglycol; 2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethanol; 3,6,9,12-Tetraoxatetradecane-1,14-diol
Molecular FormulaHO(CH2CH2O)5H
Molecular Weight238.28
Purity98%
Density1.1±0.1 g/cm3
Boiling Point184 °C/2 mmHg (lit.)
Appearanceliquid
EINECS225-341-4
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 4792-15-8 |
| Catalog No. | 2A-0201878 |
| Chinese Name | 五甘醇 |
| Synonyms | Pentaethylene Glycol; 3,6,9,12-Tetraoxatetradecane-1,14-diol,Pentaglycol; MFCD00002878; EINECS 225-341-4; pentaethyleneglycol; 2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethanol; 3,6,9,12-Tetraoxatetradecane-1,14-diol |
| Molecular Formula | HO(CH2CH2O)5H |
| Molecular Weight | 238.28 |
| Purity | 98 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 184 °C/2 mmHg (lit.) |
| Appearance | liquid |
| Storage Condition | Store at room temperature, away from light, in a v |
| Application | Pentaethylene glycol is a PROTAC linker, belonging to the PEG class. Can be used to synthesize PROTAC molecules. |
| EINECS | 225-341-4 |
| HTC | 2909499000 |
| PubChem ID | 24860343 |
| MDL Number | MFCD00002878 |
| SMILES | OCCOCCOCCOCCOCCO |
| InChI | 1S/C10H22O6/c11-1-3-13-5-7-15-9-10-16-8-6-14-4-2-12/h11-12H,1-10H2 |
| InChI Key | JLFNLZLINWHATN-UHFFFAOYSA-N |
| Beilstein/REAXYS | 1635593 |
| NACRES Code | NA.23 |
| UNSPSC | 12162002 |
| Hazard Symbols | transportation |
| MSDS | msds/31214_1_4792_15_8.pdf |
| Bioactivity | Pentaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker Target PEGs In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 356.1±32.0 °C at 760 mmHg Molecular Formula C10H22O6 Molecular Weight 238.278 Flash Point 169.2±25.1 °C Exact Mass 238.141632 PSA 77.38000 LogP -2.59 Vapour Pressure 0.0±1.8 mmHg at 25°C Index of Refraction 1.458 InChIKey JLFNLZLINWHATN-UHFFFAOYSA-N SMILES OCCOCCOCCOCCOCCO Stability Stable. Combustible. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides. |
| Use of | Pentaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Properties Name Pentaethylene glycol Synonym More Synonyms Pentaethylene glycol Biological Activity Description Pentaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 Chemical & Physical Properties Molecular Formula C10H22O6 Exact Mass 238.141632 PSA 77.38000 LogP -2.59 Index of Refraction 1.458 InChIKey JLFNLZLINWHATN-UHFFFAOYSA-N SMILES OCCOCCOCCOCCOCCO Stability Stable. Combustible. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides. |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 5.5% Ordinary tariff: 30.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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