CAS Number4330-99-8
SynonymsTrimeprazine Tartrate; 10-[3-(Dimethylamino)-2-methylpropyl]phenothiazine Tartrate; 10H-Phenothiazine-10-propanamine, N,N,β-trimethyl-, 2,3-dihydroxybutanedioate (1:1) (salt); Alimemazine; EINECS 224-368-9; N,N,2-trimethyl-3-(10H-phenothiazin-10-yl)propan-1-amine 2,3-dihydroxybutanedioate (1:1); N,N,2-Trimethyl-3-(10H-phenothiazin-10-yl)-1-propanamine 2,3-dihydroxysuccinate (1:1); MFCD00242594
Molecular FormulaC18H22N2S.1/2C4H6O6
Molecular Weight373.49
Purity99.00%
Melting Point>300 °C(lit.)
AppearanceSolid;White to Almost white powder to crystal
EINECS224-368-9
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 4330-99-8 |
| Catalog No. | 2A-9030777 |
| Chinese Name | 阿利马嗪酒石酸盐 |
| Synonyms | Trimeprazine Tartrate; 10-[3-(Dimethylamino)-2-methylpropyl]phenothiazine Tartrate; 10H-Phenothiazine-10-propanamine, N,N,β-trimethyl-, 2,3-dihydroxybutanedioate (1:1) (salt); Alimemazine; EINECS 224-368-9; N,N,2-trimethyl-3-(10H-phenothiazin-10-yl)propan-1-amine 2,3-dihydroxybutanedioate (1:1); N,N,2-Trimethyl-3-(10H-phenothiazin-10-yl)-1-propanamine 2,3-dihydroxysuccinate (1:1); MFCD00242594 |
| Molecular Formula | C18H22N2S.1/2C4H6O6 |
| Molecular Weight | 373.49 |
| Purity | 99.00 |
| Melting Point | >300 °C(lit.) |
| Appearance | Solid;White to Almost white powder to crystal |
| Storage Condition | Store at room temperature, away from light, in a v |
| Packaging | III |
| Application | Alimemazine hemitartrate is a phenothiazine derivative commonly used as an antipruritic agent and an antagonist of the hemagglutinin (HA)-receptor. |
| EINECS | 224-368-9 |
| HTC | 2934300000 |
| SMILES | S4c5c(cccc5)N(c6c4cccc6)CC(CN(C)C)C.S1c2c(cccc2)N(c3c1cccc3)CC(CN(C)C)C.O[C@H]([C@@H](O)C(=O)O)C(=O)O |
| InChI | 1S/2C18H22N2S.C4H6O6/c2*1-14(12-19(2)3)13-20-15-8-4-6-10-17(15)21-18-11-7-5-9-16(18)20;5-1(3(7)8)2(6)4(9)10/h2*4-11,14H,12-13H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/t;;1-,2-/m..1/s1 |
| InChI Key | AJZJIYUOOJLBAU-CEAXSRTFSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | 6.1(b) |
| MSDS | msds/30777_1_4330_99_8.pdf |
| Bioactivity | Alimemazine hemitartrate is a phenothiazine derivative that is generally used as an antipruritic agent and also a hemagglutinin (HA)-receptor antagonist. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease Research Areas >> Inflammation/Immunology Target HA receptor[1] References [1]. Singh B, et al. Bioanalytical method development and validation of alimemazine in human plasma by LC-MS/MS and its application in bioequivalence studies. J Pharm Bioallied Sci. 2013 Oct;5(4):257-64. Chemical & Physical Properties Melting Point >300 °C(lit.) Molecular Formula C18H22N2S.1/2C4H6O6 Molecular Weight 373.49 PSA 178.62000 LogP 6.98140 InChIKey AJZJIYUOOJLBAU-RNKHSWPKSA-N SMILES CC(CN(C)C)CN1c2ccccc2Sc2ccccc21.CC(CN(C)C)CN1c2ccccc2Sc2ccccc21.O=C(O)C(O)C(O)C(=O)O Storage condition Refrigerator |
| Use of | Alimemazine hemitartrate is a phenothiazine derivative that is generally used as an antipruritic agent and also a hemagglutinin (HA)-receptor antagonist. Properties Name Alimemazine hemitartrate Synonym More Synonyms Alimemazine hemitartrate Biological Activity Description Alimemazine hemitartrate is a phenothiazine derivative that is generally used as an antipruritic agent and also a hemagglutinin (HA)-receptor antagonist. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease Research Areas >> Inflammation/Immunology HA receptor[1] References [1]. Singh B, et al. Bioanalytical method development and validation of alimemazine in human plasma by LC-MS/MS and its application in bioequivalence studies. J Pharm Bioallied Sci. 2013 Oct;5(4):257-64. Chemical & Physical Properties PSA 178.62000 LogP 6.98140 InChIKey AJZJIYUOOJLBAU-RNKHSWPKSA-N Storage condition Refrigerator |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: Item 1 Poisons. UN number: 2811 Proper Shipping Name: Toxic Solid, Organic, Not Otherwise Specified Packing grade: III |
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