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Streptomycin sulfate structure, CAS 3810-74-0

Streptomycin sulfate

CAS Number3810-74-0

SynonymsMFCD00037023; Streptomycin sulfate salt; Streptomycin Sulfate; EINECS 223-286-0; Streptomycin Sulphate; Streptomycin (sulfate)

Molecular FormulaC21H39N7O12 · 1.5 H2SO4

Molecular Weight728.69

Purity98.00%

Density

Boiling Point948.2ºC at 760 mmHg

Melting Point

Flash Point

Appearancepowder

EINECS223-286-0

MSDSChineseEnglish

Symbol6.1

Signal WordWarning

Cat. No.: 2A-9030209 Purity: 98.00%
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Quality Control of [ 3810-74-0 ] Purity: 98.00% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number3810-74-0
Catalog No.2A-9030209
Chinese Name硫酸链霉素
SynonymsMFCD00037023; Streptomycin sulfate salt; Streptomycin Sulfate; EINECS 223-286-0; Streptomycin Sulphate; Streptomycin (sulfate)
Molecular FormulaC21H39N7O12 · 1.5 H2SO4
Molecular Weight728.69
Purity98.00
Boiling Point948.2ºC at 760 mmHg
Appearancepowder
Water Solubility≥0.01 G/100 ML AT 18 ºC
Storage ConditionSealed at 4℃, protected from light, in a ventilate
ApplicationStreptomycin sulfate is an aminoglycoside antibiotic that inhibits protein synthesis.
EINECS223-286-0
HTC2941200000
PubChem ID24899828
MDL NumberMFCD00037023
SMILESOS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]2[C@@H](O[C@@H](C)[C@]2(O)C=O)O[C@@H]3[C@@H](O)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]3NC(N)=N.CN[C@H]4[C@H](O)[C@@H](O)[C@H](CO)O[C@H]4O[C@H]5[C@@H](O[C@@H](C)[C@]5(O)C=O)O[C@@H]6[C@@H](O)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]6NC(N)=N
InChI1S/2C21H39N7O12.3H2O4S/c2*1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;3*1-5(2,3)4/h2*4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28);3*(H2,1,2,3,4)/t2*5-,6-,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,21+;;;/m00.../s1
InChI KeyQTENRWWVYAAPBI-YZTFXSNBSA-N
Beilstein/REAXYS3894995
NACRES CodeNA.76
UNSPSC51281675
Hazard Symbols6.1
MSDSmsds/30209_1_3810_74_0.pdf
BioactivityStreptomycin sulfate is an aminoglycoside antibiotic, that inhibits protein synthesis. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection In Vitro Strain RB1 shows enhanced susceptibility to streptomycin as the concentration of CV in the growth medium increases. As the CV concentration in the growth medium increases, both cytochrome aa3 levels and streptomycin susceptibility increase. Cytochrome aa3 is necessary for accumulation of streptomycin by B. subtilis[1]. Streptomycin influences tRNA selection. Streptomycin resistance mutations generally map to protein S12 and most of these variants exhibit increased levels of discrimination in the tRNA selection process[2]. References [1]. McEnroe AS, et al. Correlation between cytochrome aa3 concentrations and streptomycin accumulation in Bacillus subtilis. Antimicrob Agents Chemother. 1984 Oct;26(4):507-12. [2]. Sharma, D., et al., Mutational analysis of S12 protein and implications for the accuracy of decoding by the ribosome. J Mol Biol, 2007. 374(4): p. 1065-76. Chemical & Physical Properties Boiling Point 948.2ºC at 760 mmHg Molecular Formula C21H42N7O18S1.5 Molecular Weight 728.69 Flash Point 527.3ºC PSA 911.80000 Index of Refraction -85 ° (C=1, H2O) InChIKey QTENRWWVYAAPBI-YZTFXSNBSA-N SMILES CNC1C(OC2C(OC3C(O)C(O)C(N=C(N)N)C(O)C3N=C(N)N)OC(C)C2(O)C=O)OC(CO)C(O)C1O.CNC1C(OC2C(OC3C(O)C(O)C(N=C(N)N)C(O)C3N=C(N)N)OC(C)C2(O)C=O)OC(CO)C(O)C1O.O=S(=O)(O)O.O=S(=O)(O)O.O=S(=O)(O)O Storage condition 2-8°C Stability Stable. Incompatible with strong oxidizing agents. Water Solubility ≥0.01 G/100 ML AT 18 ºC
Use ofStreptomycin sulfate is an aminoglycoside antibiotic, that inhibits protein synthesis. Properties Articles708 Name streptomycin sesquisulfate Synonym More Synonyms Steptomycin sulfate Biological Activity Description Streptomycin sulfate is an aminoglycoside antibiotic, that inhibits protein synthesis. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [2]. Sharma, D., et al., Mutational analysis of S12 protein and implications for the accuracy of decoding by the ribosome. J Mol Biol, 2007. 374(4): p. 1065-76. Chemical & Physical Properties Molecular Formula C21H42N7O18S1.5 PSA 911.80000 InChIKey QTENRWWVYAAPBI-YZTFXSNBSA-N Stability Stable. Incompatible with strong oxidizing agents. Water Solubility ≥0.01 G/100 ML AT 18 ºC
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified Streptomycin sulfate Modification number: 6
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