CAS Number3567-69-9
SynonymsDisodium 4-hydroxy-3-((4-sulphonatonaphthyl)azo)naphthalenesulphonate; Carmoisine B; Disodium 4-hydroxy-3-[(E)-(4-sulfonato-1-naphthyl)diazenyl]-1-naphthalenesulfonate; Disodium 4-hydroxy-3-[(E)-(4-sulfonato-1-naphthyl)diazenyl]naphthalene-1-sulfonate; 1-Naphthalenesulfonic acid, 4-hydroxy-3-[(E)-2-(4-sulfo-1-naphthalenyl)diazenyl]-, sodium salt (1:2); disodium 4-hydroxy-3-[(E)-(4-sulfonato-1-naphthyl)azo]naphthalene-1-sulfonate; EINECS 222-657-4; foodred5; 4-hydroxy-3,4'-azo-bis-naphthalene-1-sulfonic acid,disodium-salt; red#14; Mordant Blue 79; Chromotrope FB; carmoisin; disodium 4-hydroxy-3-[(E)-(4-sulfonatonaphthalen-1-yl)diazenyl]naphthalene-1-sulfonate; AZORUBIN; Azorubine; Brilliant Crimson Red; MFCD00003978; E122; 1-naphthalenesulfonic acid, 4-hydroxy-3-[(E)-(4-sulfo-1-naphthalenyl
Molecular FormulaC20H12N2Na2O7S2
Molecular Weight502.43
Purity98.00%
Melting Point>300ºC
Appearancered powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 3567-69-9 |
| Catalog No. | 2A-9029943 |
| Chinese Name | 铬变素FB |
| Synonyms | Disodium 4-hydroxy-3-((4-sulphonatonaphthyl)azo)naphthalenesulphonate; Carmoisine B; Disodium 4-hydroxy-3-[(E)-(4-sulfonato-1-naphthyl)diazenyl]-1-naphthalenesulfonate; Disodium 4-hydroxy-3-[(E)-(4-sulfonato-1-naphthyl)diazenyl]naphthalene-1-sulfonate; 1-Naphthalenesulfonic acid, 4-hydroxy-3-[(E)-2-(4-sulfo-1-naphthalenyl)diazenyl]-, sodium salt (1:2); disodium 4-hydroxy-3-[(E)-(4-sulfonato-1-naphthyl)azo]naphthalene-1-sulfonate; EINECS 222-657-4; foodred5; 4-hydroxy-3,4'-azo-bis-naphthalene-1-sulfonic acid,disodium-salt; red#14; Mordant Blue 79; Chromotrope FB; carmoisin; disodium 4-hydroxy-3-[(E)-(4-sulfonatonaphthalen-1-yl)diazenyl]naphthalene-1-sulfonate; AZORUBIN; Azorubine; Brilliant Crimson Red; MFCD00003978; E122; 1-naphthalenesulfonic acid, 4-hydroxy-3-[(E)-(4-sulfo-1-naphthalenyl |
| Molecular Formula | C20H12N2Na2O7S2 |
| Molecular Weight | 502.43 |
| Purity | 98.00 |
| Melting Point | >300ºC |
| Appearance | red powder |
| Storage Condition | Keep away from light, in a ventilated and dry plac |
| Application | Carmoisine (Azorubine) is an azo dye used as a food additive. |
| PubChem ID | 14908914 |
| SMILES | O=S(=O)([O-])c1ccc(N=Nc2cc(S(=O)(=O)[O-])c3ccccc3c2O)c2ccccc12.[Na+].[Na+] |
| InChI | InChI=1S/C20H14N2O7S2.2Na/c23-20-15-8-4-3-7-14(15)19(31(27,28)29)11-17(20)22-21-16-9-10-18(30(24,25)26)13-6-2-1-5-12(13)16;;/h1-11,21H,(H,24,25,26)(H,27,28,29);;/q;2*+1/p-2/b22-17+;; |
| InChI Key | YSVBPNGJESBVRM-UHFFFAOYSA-L |
| Hazard Symbols | transportation |
| Bioactivity | Carmoisine (Azorubine) is an azo dye that can be used as a food additive[1][2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology In Vitro Carmoisine augments the in vitro synthesis of leukotriene B4 (LTB4) and F2-isoprostanes from blood neutrophils. Carmoisine increases the formation of F2-isoprostanes from blood neutrophils at all tested concentrations[2]. In Vivo Carmoisine (49.3-493 mg/kg; oral administration; for 42 days; male Wistar rats) treatment increases MAPK8 expression at remarkably low and high concentrations, the expression of NFκB and GADD45α does not change[1]. Animal Model: Male Wistar rats (120-300 g)[1] Dosage: 49.3 mg/kg, 493 mg/kg Administration: Oral administration; for 42 days Result: Resulted in apoptosis according to MAPK8 expression. References [1]. B Raposa, et al. Food additives: Sodium benzoate, potassium sorbate, azorubine, and tartrazine modify the expression of NFκB, GADD45α, and MAPK8 genes. Physiol Int. 2016 Sep;103(3):334-343. [2]. Latasha Leo, et al. Occurrence of azo food dyes and their effects on cellular inflammatory responses. Nutrition. 2018 Feb;46:36-40. Chemical & Physical Properties Melting Point >300ºC Molecular Formula C20H12N2Na2O7S2 Molecular Weight 502.428 Flash Point >225℃ Exact Mass 501.988129 PSA 176.11000 LogP 6.08380 InChIKey YSVBPNGJESBVRM-UHFFFAOYSA-L SMILES O=S(=O)([O-])c1ccc(N=Nc2cc(S(=O)(=O)[O-])c3ccccc3c2O)c2ccccc12.[Na+].[Na+] |
| Use of | Carmoisine (Azorubine) is an azo dye that can be used as a food additive[1][2]. Properties Articles26 Name Acidic Red B Synonym More Synonyms Carmoisine Biological Activity Description Carmoisine (Azorubine) is an azo dye that can be used as a food additive[1][2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology In Vitro Carmoisine augments the in vitro synthesis of leukotriene B4 (LTB4) and F2-isoprostanes from blood neutrophils. Carmoisine increases the formation of F2-isoprostanes from blood neutrophils at all tested concentrations[2]. References [2]. Latasha Leo, et al. Occurrence of azo food dyes and their effects on cellular inflammatory responses. Nutrition. 2018 Feb;46:36-40. Chemical & Physical Properties Molecular Formula C20H12N2Na2O7S2 Exact Mass 501.988129 PSA 176.11000 LogP 6.08380 InChIKey YSVBPNGJESBVRM-UHFFFAOYSA-L |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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