CAS Number3386-18-3
Synonymspolyethylene glycol; 3,6,9,12,15,18,21,24-Octaoxahexacosane-1,26-diol; EINECS 222-206-1; nonaneethylene glycol; 2PE; 1icj; 2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
Molecular FormulaC18H38O10
Molecular Weight414.49
Purity98.00%
Density1.1±0.1 g/cm3
Boiling Point506.2±45.0 °C at 760 mmHg
AppearanceWhite - very light yellow waxy solid
EINECS222-206-1
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 3386-18-3 |
| Catalog No. | 2A-9029739 |
| Chinese Name | 九甘醇 |
| Synonyms | polyethylene glycol; 3,6,9,12,15,18,21,24-Octaoxahexacosane-1,26-diol; EINECS 222-206-1; nonaneethylene glycol; 2PE; 1icj; 2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol |
| Molecular Formula | C18H38O10 |
| Molecular Weight | 414.49 |
| Purity | 98.00 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 506.2±45.0 °C at 760 mmHg |
| Appearance | White - very light yellow waxy solid |
| Storage Condition | Store at room temperature, away from light, in a v |
| Application | Nonaethylene glycol is a PROTAC linker, belonging to the PEG class. Can be used to synthesize PROTAC molecules. |
| EINECS | 222-206-1 |
| HTC | 2909499000 |
| PubChem ID | 822603 |
| MDL Number | MFCD00698692 |
| SMILES | OCCOCCOCCOCCOCCOCCOCCOCCOCCO |
| InChI | InChI=1S/C18H38O10/c19-1-3-21-5-7-23-9-11-25-13-15-27-17-18-28-16-14-26-12-10-24-8-6-22-4-2-20/h19-20H,1-18H2 |
| InChI Key | YZUUTMGDONTGTN-UHFFFAOYSA-N |
| MSDS | msds/29739_1_3386_18_3.pdf |
| Bioactivity | Nonaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker Target PEGs In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 506.2±45.0 °C at 760 mmHg Molecular Formula C18H38O10 Molecular Weight 414.488 Flash Point 260.0±28.7 °C Exact Mass 414.246490 PSA 114.30000 LogP -4.02 Vapour Pressure 0.0±3.0 mmHg at 25°C Index of Refraction 1.464 InChIKey YZUUTMGDONTGTN-UHFFFAOYSA-N SMILES OCCOCCOCCOCCOCCOCCOCCOCCOCCO |
| Use of | Nonaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Properties Name nonaethylene glycol Synonym More Synonyms nonaethylene glycol Biological Activity Description Nonaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 Chemical & Physical Properties Molecular Formula C18H38O10 Exact Mass 414.246490 PSA 114.30000 LogP -4.02 Index of Refraction 1.464 InChIKey YZUUTMGDONTGTN-UHFFFAOYSA-N SMILES OCCOCCOCCOCCOCCOCCOCCOCCOCCO |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 5.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 95.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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