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6-Carboxyfluoresceine diacetate structure, CAS 3348-03-6

6-Carboxyfluoresceine diacetate

CAS Number3348-03-6

Synonyms6-FAM DA; 6-CFDA 6-Carboxy-di-O-acetylfluorescein; 6-CFDA; MFCD00036871; 6-Carboxyfluorescein diacetate; 3',6'-Diacetoxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-6-carboxylic acid; 6-Carboxy-di-O-acetylfluorescein,6-CFDA; 5,6-diacetyl FAM-SE; 6-CARBOXY-DI-O-ACETYLFLUORESCEIN; 3',6'-Diacetoxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-6-carboxylic acid; 6-FAM DIACETATE; 6-Carboxyfluorescein diacetate,6-CFDA,6-Carboxy-di-O-acetylfluorescein; 6-CARBOXYFLUORESCEINE DIACETATE

Molecular FormulaC25H16O9

Molecular Weight460.39

Purity≥95 (HPLC)%

Density1.6±0.1 g/cm3

Boiling Point701.6±60.0 °C at 760 mmHg

Melting Point152-153°C

Flash Point

Appearancepowder

EINECS

MSDSChineseEnglish

Symboltransportation

Signal WordWarning

Cat. No.: 2A-9029700 Purity: ≥95 (HPLC)%
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Quality Control of [ 3348-03-6 ] Purity: ≥95 (HPLC)% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number3348-03-6
Catalog No.2A-9029700
Chinese Name6-羧基荧光素二乙酸酯
Synonyms6-FAM DA; 6-CFDA 6-Carboxy-di-O-acetylfluorescein; 6-CFDA; MFCD00036871; 6-Carboxyfluorescein diacetate; 3',6'-Diacetoxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-6-carboxylic acid; 6-Carboxy-di-O-acetylfluorescein,6-CFDA; 5,6-diacetyl FAM-SE; 6-CARBOXY-DI-O-ACETYLFLUORESCEIN; 3',6'-Diacetoxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-6-carboxylic acid; 6-FAM DIACETATE; 6-Carboxyfluorescein diacetate,6-CFDA,6-Carboxy-di-O-acetylfluorescein; 6-CARBOXYFLUORESCEINE DIACETATE
Molecular FormulaC25H16O9
Molecular Weight460.39
Purity≥95 (HPLC)
Density1.6±0.1 g/cm3
Boiling Point701.6±60.0 °C at 760 mmHg
Melting Point152-153°C
Appearancepowder
Water SolubilityDMSO: soluble
Storage ConditionStore at room temperature, away from light, in a v
Application6-CFDA is a polyanionic fluorescent probe.
HTC2932999099
PubChem ID24892748
MDL NumberMFCD00036871
SMILESCC(=O)Oc1ccc2c(Oc3cc(OC(C)=O)ccc3C24OC(=O)c5ccc(cc45)C(O)=O)c1
InChI1S/C25H16O9/c1-12(26)31-15-4-7-18-21(10-15)33-22-11-16(32-13(2)27)5-8-19(22)25(18)20-9-14(23(28)29)3-6-17(20)24(30)34-25/h3-11H,1-2H3,(H,28,29)
InChI KeyQMOGCCYGOPYYNT-UHFFFAOYSA-N
Beilstein/REAXYS67043
NACRES CodeNA.47
UNSPSC12171500
Hazard Symbolstransportation
MSDSmsds/29700_1_3348_03_6.pdf
Bioactivity6-CFDA is fluorescent polyanionic probe, and its derivatives such as 2′,7′-bis (2-carboxyethyl)-5(6)-carboxyfluorescein are used to measure changes in intracellular pH (pHi) and processes such as dendrimer aggregation and absorption. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Others Dye Reagents References [1]. Babcock DF. Examination of the intracellular ionic environment and of ionophore action by null point measurements employing the fluorescein chromophore. J Biol Chem. 1983 May 25;258(10):6380-9. [2]. Graber ML, et al. Characteristics of fluoroprobes for measuring intracellular pH. Anal Biochem. 1986 Jul;156(1):202-12. [3]. Bonizzoni M, et al. PAMAM dendrimer-induced aggregation of 5(6)-carboxyfluorescein. J Org Chem. 2012 Feb 3;77(3):1258-66. Chemical & Physical Properties Density 1.6±0.1 g/cm3 Boiling Point 701.6±60.0 °C at 760 mmHg Melting Point 152-153°C Molecular Formula C25H16O9 Molecular Weight 460.389 Flash Point 245.1±26.4 °C Exact Mass 460.079437 PSA 125.43000 LogP 2.45 Appearance of Characters Light yellow or off-white solid Vapour Pressure 0.0±2.3 mmHg at 25°C Index of Refraction 1.702 InChIKey QMOGCCYGOPYYNT-UHFFFAOYSA-N SMILES CC(=O)Oc1ccc2c(c1)Oc1cc(OC(C)=O)ccc1C21OC(=O)c2ccc(C(=O)O)cc21 Storage condition 2-8°C Water Solubility DMSO: soluble
Use of6-CFDA is fluorescent polyanionic probe, and its derivatives such as 2′,7′-bis (2-carboxyethyl)-5(6)-carboxyfluorescein are used to measure changes in intracellular pH (pHi) and processes such as dendrimer aggregation and absorption. Properties Articles37 Name 6-carboxyfluorescein diacetate Synonym More Synonyms 6-Carboxyfluorescein Diacetate Biological Activity Description 6-CFDA is fluorescent polyanionic probe, and its derivatives such as 2′,7′-bis (2-carboxyethyl)-5(6)-carboxyfluorescein are used to measure changes in intracellular pH (pHi) and processes such as dendrimer aggregation and absorption. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Others Dye Reagents References [1]. Babcock DF. Examination of the intracellular ionic environment and of ionophore action by null point measurements employing the fluorescein chromophore. J Biol Chem. 1983 May 25;258(10):6380-9. [2]. Graber ML, et al. Characteristics of fluoroprobes for measuring intracellular pH. Anal Biochem. 1986 Jul;156(1):202-12. [3]. Bonizzoni M, et al. PAMAM dendrimer-induced aggregation of 5(6)-carboxyfluorescein. J Org Chem. 2012 Feb 3;77(3):1258-66. Chemical & Physical Properties Molecular Formula C25H16O9 Exact Mass 460.079437 PSA 125.43000 Appearance of Characters Light yellow or off-white solid Index of Refraction 1.702 InChIKey QMOGCCYGOPYYNT-UHFFFAOYSA-N Water Solubility DMSO: soluble
Tax Rebate13.0%
SupervisionNone. MFN tariff: 6.5%. Ordinary tariff: 20.0%
Transport InfoProduct name: Purity: 95.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available
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