
CAS Number3326-34-9
SynonymsFluoresceinamine (isomer I); Fluoresceinamine; 1-AMINOFLUORESCEIN; 5-Amino-3',6'-dihydroxy-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one; 1-FLUORESCEINAMINE; EINECS 222-043-6; FLUORESCEINAMINE ISOMER I; 4-AMINOFLUORESCEIN ISOMER I; MFCD00005052; 5-Aminofluorescein; AMINOFLUORESCEIN; 5-Amino-3',6'-dihydroxy-3H-spiro[2-benzofuran-1,9'-xanthen]-3-on; FLUORESCEINAMINE,ISOMER 1; 5-fluorescein amine; Fluoresceinamine-I; 5-Aminofluorescein (isomer I); 4-AMINOFLUORESCEIN; Fluoresceinamine,isomer I; 5-Amino-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-(9H)xanthen]-3-one (isomer I)
Molecular FormulaC20H13NO5
Molecular Weight347.321
Purity98.00%
Density1.6±0.1 g/cm3
Boiling Point695.3±55.0 °C at 760 mmHg
Melting Point223ºC
Appearancedark brown solid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 3326-34-9 |
| Catalog No. | 2A-9029678 |
| Chinese Name | 5-氨基荧光素 |
| Synonyms | Fluoresceinamine (isomer I); Fluoresceinamine; 1-AMINOFLUORESCEIN; 5-Amino-3',6'-dihydroxy-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one; 1-FLUORESCEINAMINE; EINECS 222-043-6; FLUORESCEINAMINE ISOMER I; 4-AMINOFLUORESCEIN ISOMER I; MFCD00005052; 5-Aminofluorescein; AMINOFLUORESCEIN; 5-Amino-3',6'-dihydroxy-3H-spiro[2-benzofuran-1,9'-xanthen]-3-on; FLUORESCEINAMINE,ISOMER 1; 5-fluorescein amine; Fluoresceinamine-I; 5-Aminofluorescein (isomer I); 4-AMINOFLUORESCEIN; Fluoresceinamine,isomer I; 5-Amino-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-(9H)xanthen]-3-one (isomer I) |
| Molecular Formula | C20H13NO5 |
| Molecular Weight | 347.321 |
| Purity | 98.00 |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 695.3±55.0 °C at 760 mmHg |
| Melting Point | 223ºC |
| Appearance | dark brown solid |
| Storage Condition | 1. This product should be sealed with argon gas an |
| Application | 5-Aminofluorescein (5-AF) is a novel fluorescent label covalently bound to human serum albumin. |
| HTC | 2921199090 |
| PubChem ID | 598015 |
| SMILES | Nc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21 |
| InChI | InChI=1S/C20H13NO5/c21-10-1-4-14-13(7-10)19(24)26-20(14)15-5-2-11(22)8-17(15)25-18-9-12(23)3-6-16(18)20/h1-9,22-23H,21H2 |
| InChI Key | GZAJOEGTZDUSKS-UHFFFAOYSA-N |
| Hazard Symbols | transportation |
| Bioactivity | 5-Aminofluorescein (5-AF) is a new fluorescence marker, covalently bound to human serum albumin (AFL-HSA) [1]5-aminofluorescein is a pH-sensitive biomaterial, is the targeted prodrug for synthesis of FA-FITC-Arg-PTX and FA-5AF- Glu-PTX.. Related Catalog Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others References [1]. Ding R, et al. Pharmacokinetics of 5-aminofluorescein-albumin, a novel fluorescence marker of brain tumors during surgery. J Clin Pharmacol. 2011 May;51(5):672-8. [2]. Miao R, et al. Facile method for modification of the silicon nanowires and its application in fabrication of pH-sensitive chips. ACS Appl Mater Interfaces. 2013 Mar 13;5(5):1741-6. [3]. Wang T, et al. Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein. J Am Chem Soc. 2015 Nov 4;137(43):13736-9. [4]. Shan L, et al. Multi-small molecule conjugations as new targeted delivery carriers for tumor therapy. Int J Nanomedicine. 2015 Sep 1;10:5571-91. Chemical & Physical Properties Density 1.6±0.1 g/cm3 Boiling Point 695.3±55.0 °C at 760 mmHg Melting Point 223ºC Molecular Formula C20H13NO5 Molecular Weight 347.321 Flash Point 374.3±31.5 °C Exact Mass 347.079376 PSA 102.01000 LogP 1.80 Vapour Pressure 0.0±2.3 mmHg at 25°C Index of Refraction 1.820 InChIKey GZAJOEGTZDUSKS-UHFFFAOYSA-N SMILES Nc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21 Storage condition 2-8°C Stability Light and Moisture Sensitive |
| Use of | 5-Aminofluorescein (5-AF) is a new fluorescence marker, covalently bound to human serum albumin (AFL-HSA) [1]5-aminofluorescein is a pH-sensitive biomaterial, is the targeted prodrug for synthesis of FA-FITC-Arg-PTX and FA-5AF- Glu-PTX.. Properties Articles30 Name 6-amino-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one Synonym More Synonyms 5-Aminofluorescein Biological Activity Description 5-Aminofluorescein (5-AF) is a new fluorescence marker, covalently bound to human serum albumin (AFL-HSA) [1]5-aminofluorescein is a pH-sensitive biomaterial, is the targeted prodrug for synthesis of FA-FITC-Arg-PTX and FA-5AF- Glu-PTX.. Related Catalog Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others References [1]. Ding R, et al. Pharmacokinetics of 5-aminofluorescein-albumin, a novel fluorescence marker of brain tumors during surgery. J Clin Pharmacol. 2011 May;51(5):672-8. [2]. Miao R, et al. Facile method for modification of the silicon nanowires and its application in fabrication of pH-sensitive chips. ACS Appl Mater Interfaces. 2013 Mar 13;5(5):1741-6. [3]. Wang T, et al. Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein. J Am Chem Soc. 2015 Nov 4;137(43):13736-9. [4]. Shan L, et al. Multi-small molecule conjugations as new targeted delivery carriers for tumor therapy. Int J Nanomedicine. 2015 Sep 1;10:5571-91. Chemical & Physical Properties Molecular Formula C20H13NO5 Exact Mass 347.079376 PSA 102.01000 Index of Refraction 1.820 InChIKey GZAJOEGTZDUSKS-UHFFFAOYSA-N Stability Light and Moisture Sensitive |
| Tax Rebate | 9.0% |
| Supervision | none |
| Transport Info | Product name: Purity: 96.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: No dangerous goods IMDG Code: No dangerous goods International Air Transport Dangerous Regulations: No dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special precautions for users No data available The company is not responsible for any damage caused by any operation or contact with the above products. For more terms of use, see invoice or package The reverse side of the mounting strip. |
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