CAS Number2942-42-9
Synonyms1H-Indazole,7-nitro; MFCD00022789; nitro-7 indazole; 7-Nitroindazole; 7-NI; 7-Nitro-1H-indazole; 7-Nitro-2H-indazole; EINECS 220-934-4
Molecular FormulaC7H5N3O2
Molecular Weight163.13
Purity≥98%
Density1.5±0.1 g/cm3
Boiling Point211.2±23.0 °C at 760 mmHg
Melting Point185-186°C
Appearancepowder
EINECS220-934-4
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 2942-42-9 |
| Catalog No. | 2A-9029230 |
| Chinese Name | 7-硝基吲唑 |
| Synonyms | 1H-Indazole,7-nitro; MFCD00022789; nitro-7 indazole; 7-Nitroindazole; 7-NI; 7-Nitro-1H-indazole; 7-Nitro-2H-indazole; EINECS 220-934-4 |
| Molecular Formula | C7H5N3O2 |
| Molecular Weight | 163.13 |
| Purity | ≥98 |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 211.2±23.0 °C at 760 mmHg |
| Melting Point | 185-186°C |
| Appearance | powder |
| Water Solubility | slightly soluble |
| Storage Condition | Sealed in a cool, dry environment at -20 ºC |
| Application | 7-Nitroindazole is a selective nNOS inhibitor with antinociceptive and cardiovascular effects. 7-Nitroindazole is a useful tool for assessing the biological role of nitric oxide in the central nervous |
| EINECS | 220-934-4 |
| HTC | 2933990090 |
| PubChem ID | 24278047 |
| MDL Number | MFCD00022789 |
| SMILES | [O-][N+](=O)c1cccc2cn[nH]c12 |
| InChI | 1S/C7H5N3O2/c11-10(12)6-3-1-2-5-4-8-9-7(5)6/h1-4H,(H,8,9) |
| InChI Key | PQCAUHUKTBHUSA-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| Hazard Symbols | 6.1 |
| MSDS | msds/29230_1_2942_42_9.pdf |
| Bioactivity | 7-Nitroindazole is a selective nNOS inhibitor with antinociceptive and cardiovascular effects. 7-Nitroindazole is a useful tool to evaluate the biological roles of nitric oxide in the central nervous system[1][2]. Related Catalog Research Areas >> Cardiovascular Disease Signaling Pathways >> Immunology/Inflammation >> NO Synthase Research Areas >> Neurological Disease References [1]. Moore PK, et al. 7-Nitro indazole, an inhibitor of nitric oxide synthase, exhibits anti-nociceptive activity in the mouse without increasing blood pressure. Br J Pharmacol. 1993 Feb;108(2):296-7. [2]. Moore PK, et al. Characterization of the novel nitric oxide synthase inhibitor 7-nitro indazole and related indazoles: antinociceptive and cardiovascular effects. Br J Pharmacol. 1993 Sep;110(1):219-24. Chemical & Physical Properties Density 1.5±0.1 g/cm3 Boiling Point 211.2±23.0 °C at 760 mmHg Melting Point 185-186°C Molecular Formula C7H5N3O2 Molecular Weight 163.133 Flash Point 81.5±22.6 °C Exact Mass 163.038177 PSA 74.50000 LogP 1.42 Vapour Pressure 0.2±0.4 mmHg at 25°C Index of Refraction 1.741 InChIKey PQCAUHUKTBHUSA-UHFFFAOYSA-N SMILES O=[N+]([O-])c1cccc2cn[nH]c12 Storage condition −20°C Water Solubility slightly soluble |
| Use of | 7-Nitroindazole is a selective nNOS inhibitor with antinociceptive and cardiovascular effects. 7-Nitroindazole is a useful tool to evaluate the biological roles of nitric oxide in the central nervous system[1][2]. Properties Articles63 Name 7-nitro-1H-indazole Synonym More Synonyms 7-Nitroindazole Biological Activity Description 7-Nitroindazole is a selective nNOS inhibitor with antinociceptive and cardiovascular effects. 7-Nitroindazole is a useful tool to evaluate the biological roles of nitric oxide in the central nervous system[1][2]. Related Catalog Research Areas >> Cardiovascular Disease Signaling Pathways >> Immunology/Inflammation >> NO Synthase Research Areas >> Neurological Disease References [1]. Moore PK, et al. 7-Nitro indazole, an inhibitor of nitric oxide synthase, exhibits anti-nociceptive activity in the mouse without increasing blood pressure. Br J Pharmacol. 1993 Feb;108(2):296-7. [2]. Moore PK, et al. Characterization of the novel nitric oxide synthase inhibitor 7-nitro indazole and related indazoles: antinociceptive and cardiovascular effects. Br J Pharmacol. 1993 Sep;110(1):219-24. Chemical & Physical Properties Molecular Formula C7H5N3O2 Exact Mass 163.038177 PSA 74.50000 Index of Refraction 1.741 InChIKey PQCAUHUKTBHUSA-UHFFFAOYSA-N Water Solubility slightly soluble |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Dangerous Regulations for land transport: 2811 International Dangerous Regulations for sea transport: 2811 International Dangerous Regulations for air transport: 2811 14.2 United Nations shipping name European Land Transport Dangerous Regulations: TOXIC SOLID, ORGANIC, N.O.S. (7-Nitro-1H-indazole) IMDG Code: TOXIC SOLID, ORGANIC, N.O.S. (7-Nitro-1H-indazole) International air transport hazard regulations: Toxic solid, organic, n.o.s. (7-Nitro-1H-indazole) 14.3 Transport hazard categories European Land Transport Danger Regulations: 6.1 International Maritime Transport Danger Regulations: 6.1 International Air Transport Danger Regulations: 6.1 14.4 Package group European Land Transport Danger Regulations: III International Maritime Transport Danger Regulations: III International Air Transport Danger Regulations: III 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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