3-Chloro-L-alanine structure, CAS 2731-73-9

3-Chloro-L-alanine

CAS Number2731-73-9

Synonyms(2R)-2-amino-3-chloropropanoic acid; (R)-2-Amino-3-chloropropanoic acid; 3-Chloro-L-alanine; 2-amino-3-chloropropanoic acid; Alanine,3-chloro; L-Alanine,3-chloro; β-Chloro-L-alanine

Molecular FormulaC3H6O2N1Cl1

Molecular Weight123.54

Purity98.00%

Density1.4±0.1 g/cm3

Boiling Point243.6±30.0 °C at 760 mmHg

Melting Point156 °C

Flash Point

AppearanceWhite crystalline powder

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Cat. No.: 2A-9028947 Purity: 98.00%
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Quality Control of [ 2731-73-9 ] Purity: 98.00% SDS Specification MoL

Chemical & Physical Properties
CAS Number2731-73-9
Catalog No.2A-9028947
Chinese Name3-氯-L-丙氨酸
Synonyms(2R)-2-amino-3-chloropropanoic acid; (R)-2-Amino-3-chloropropanoic acid; 3-Chloro-L-alanine; 2-amino-3-chloropropanoic acid; Alanine,3-chloro; L-Alanine,3-chloro; β-Chloro-L-alanine
Molecular FormulaC3H6O2N1Cl1
Molecular Weight123.54
Purity98.00
Density1.4±0.1 g/cm3
Boiling Point243.6±30.0 °C at 760 mmHg
Melting Point156 °C
AppearanceWhite crystalline powder
Water SolubilitySoluble
Storage ConditionStore airtight in a cool, dry warehouse.
Applicationβ-Chloro-L-alanine is a bacteriostatic amino acid analogue that inhibits a variety of enzymes, including threonine deaminase and alanine racemase.
HTC2922499990
PubChem ID5615
MDL NumberMFCD00046536
SMILESNC(CCl)C(=O)O
InChIInChI=1S/C3H6ClNO2/c4-1-2(5)3(6)7/h2H,1,5H2,(H,6,7)/t2-/m0/s1
InChI KeyASBJGPTTYPEMLP-REOHCLBHSA-N
Safety DescriptionS24/25
MSDSmsds/28947_1_2731_73_9.pdf
Bioactivityβ-Chloro-L-alanine is a bacteriostatic amino acid analog which inhibits a number of enzymes, including threonine deaminase and alanine racemase. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection Target Bacterial[1] In Vitro β-Chloro-L-alanine can inhibit threonine deaminase, the branched-chain amino acid transaminase (transaminase B), L-aspartate-pdecarboxylase, alanine racemase and probably O-acetylserine sulfhydrylase. β-Chloro-L-alanine reversibly inhibits the Escherichia coli K-12 alanine-valine transaminase, transaminase C. This inhibition, along with the inhibition of transaminase B, account for the isoleucine-plus-valine requirement of Escherichia coli in the presence of β-Chloro-L-alanine. Salmonella typhimurium LT2 will grow in the presence of BCA if isoleucine and valine are added to the medium and presume that the growth requirement is due to the inhibition of transaminase B[1]. References [1]. β-Chloro-L-alanine can inhibits threonine deaminase, the branched-chain amino acid transaminase (transaminase B), L-aspartate-pdecarboxylase, alanine racemase and probably O-acetylserine sulfhydrylase. β-Chloro-L-alanine reversibly inhibits the Escherichia coli Chemical & Physical Properties Density 1.4±0.1 g/cm3 Boiling Point 243.6±30.0 °C at 760 mmHg Melting Point 156 °C Molecular Formula C3H6ClNO2 Molecular Weight 123.538 Flash Point 101.1±24.6 °C Exact Mass 123.008705 PSA 63.32000 LogP -0.13 Vapour Pressure 0.0±1.0 mmHg at 25°C Index of Refraction 1.499 InChIKey ASBJGPTTYPEMLP-REOHCLBHSA-N SMILES NC(CCl)C(=O)O Storage condition Store at 0°C
Use ofβ-Chloro-L-alanine is a bacteriostatic amino acid analog which inhibits a number of enzymes, including threonine deaminase and alanine racemase. Properties Name 3-chloro-L-alanine Synonym More Synonyms 3-Chloro-L-alanine Biological Activity Description β-Chloro-L-alanine is a bacteriostatic amino acid analog which inhibits a number of enzymes, including threonine deaminase and alanine racemase. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection Bacterial[1] In Vitro β-Chloro-L-alanine can inhibit threonine deaminase, the branched-chain amino acid transaminase (transaminase B), L-aspartate-pdecarboxylase, alanine racemase and probably O-acetylserine sulfhydrylase. β-Chloro-L-alanine reversibly inhibits the Escherichia coli K-12 alanine-valine transaminase, transaminase C. This inhibition, along with the inhibition of transaminase B, account for the isoleucine-plus-valine requirement of Escherichia coli in the presence of β-Chloro-L-alanine. Salmonella typhimurium LT2 will grow in the presence of BCA if isoleucine and valine are added to the medium and presume that the growth requirement is due to the inhibition of transaminase B[1]. References [1]. β-Chloro-L-alanine can inhibits threonine deaminase, the branched-chain amino acid transaminase (transaminase B), L-aspartate-pdecarboxylase, alanine racemase and probably O-acetylserine sulfhydrylase. β-Chloro-L-alanine reversibly inhibits the Escherichia coli Chemical & Physical Properties Exact Mass 123.008705 PSA 63.32000 LogP -0.13 Index of Refraction 1.499 InChIKey ASBJGPTTYPEMLP-REOHCLBHSA-N SMILES NC(CCl)C(=O)O
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