CAS Number2615-15-8
SynonymsEINECS 220-045-1; HEXAETHYLENE GLYCOL; Polyethylene glycol 300; MFCD00002877; 3,6,9,12,15-Pentaoxaheptadecane-1,17-diol; hexa-PEG-diol; 2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol; hexaethyleneglycol; PEG-6; Hexagol; Hexaoxyethylene glycol
Molecular FormulaH(OCH2CH2)6OH
Molecular Weight282.33
Purity97%
Density1.1±0.1 g/cm3
Boiling Point217 °C/4 mmHg (lit.)
Melting Point5-7 °C (lit.)
Appearanceliquid
EINECS220-045-1
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 2615-15-8 |
| Catalog No. | 2A-9028817 |
| Chinese Name | 六乙二醇 |
| Synonyms | EINECS 220-045-1; HEXAETHYLENE GLYCOL; Polyethylene glycol 300; MFCD00002877; 3,6,9,12,15-Pentaoxaheptadecane-1,17-diol; hexa-PEG-diol; 2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol; hexaethyleneglycol; PEG-6; Hexagol; Hexaoxyethylene glycol |
| Molecular Formula | H(OCH2CH2)6OH |
| Molecular Weight | 282.33 |
| Purity | 97 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 217 °C/4 mmHg (lit.) |
| Melting Point | 5-7 °C (lit.) |
| Appearance | liquid |
| Storage Condition | Sealed in a cool, dry environment. |
| Application | Hexaethylene glycol is a PROTAC linker and belongs to the PEG class. Can be used to synthesize PROTAC molecules. |
| EINECS | 220-045-1 |
| HTC | 2909499000 |
| PubChem ID | 24855697 |
| MDL Number | MFCD00002877 |
| SMILES | OCCOCCOCCOCCOCCOCCO |
| InChI | 1S/C12H26O7/c13-1-3-15-5-7-17-9-11-19-12-10-18-8-6-16-4-2-14/h13-14H,1-12H2 |
| InChI Key | IIRDTKBZINWQAW-UHFFFAOYSA-N |
| Beilstein/REAXYS | 1638281 |
| NACRES Code | NA.23 |
| UNSPSC | 12162002 |
| MSDS | msds/28817_1_2615_15_8.pdf |
| Bioactivity | Hexaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker Target PEGs In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 378.3±0.0 °C at 760 mmHg Melting Point 5-7 °C(lit.) Molecular Formula C12H26O7 Molecular Weight 282.331 Flash Point 193.7±26.5 °C Exact Mass 282.167847 PSA 86.61000 LogP -2.95 Vapour Pressure 0.0±1.9 mmHg at 25°C Index of Refraction 1.460 InChIKey IIRDTKBZINWQAW-UHFFFAOYSA-N SMILES OCCOCCOCCOCCOCCOCCO Stability Stable. Incompatible with strong oxidizing agents. |
| Use of | Hexaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Properties Articles28 Name hexaethylene glycol Synonym More Synonyms hexaethyleneglycol Biological Activity Description Hexaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 Chemical & Physical Properties Molecular Formula C12H26O7 Exact Mass 282.167847 PSA 86.61000 LogP -2.95 Index of Refraction 1.460 InChIKey IIRDTKBZINWQAW-UHFFFAOYSA-N SMILES OCCOCCOCCOCCOCCOCCO Stability Stable. Incompatible with strong oxidizing agents. |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 5.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0% |
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