![4-Aminopyrazolo[3,4-d]pyrimidine structure, CAS 2380-63-4](/structures/40000/2380-63-4.gif)
CAS Number2380-63-4
SynonymsMethyl 3-piperidinylacetate hydrochloride (1:1); 7-deaza-8-aza-adenine; 8-aza-7-deazaadenine; 1H-Pyrazolo[3,4-d]pyrimidin-4-amine; 1H-pyrazolo[3,4-d]pyrimidin-4-ylamine; EINECS 219-174-6; pyrazolo[3,4-d]pyrimidin-4-amine; Pyrazoloadenine; Aminopurinol; 4-aminopyrazolo-(3,4-d)pyrimidine; 4-aminopyrazolo[5,4-d]pyrimidine; 4-Aminopyrazolopyrimidine; 1H-Pyrazolo[3,4-d]pyrimidine-4-ylamine 4-Amino-1H-pyrazolo[3,4-d]pyrimidine; Pyrazolo[3,4-d]pyrimidin-4-amin; 4-app; ADENINE ANTIMETABOLITE; MFCD00005688; 3-Piperidineacetic acid, methyl ester, hydrochloride (1:1); 4-AMINOPYRAZOLO{3,4-D}PYRIMIDINE; 1(H)-4-amine-pyrazolo[3,4-d]pyrimidine; 4-Amino pyrazolo[3,4-d]pyrimidine
Molecular FormulaC5H5N5
Molecular Weight135.13
Purity98.00%
Density1.612g/cm3
Boiling Point431.1ºC at 760mmHg
Melting Point>325 °C(lit.)
Appearancebeige powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 2380-63-4 |
| Catalog No. | 2A-9028399 |
| Chinese Name | 4-氨基吡唑并[3,4-d]嘧啶 |
| Synonyms | Methyl 3-piperidinylacetate hydrochloride (1:1); 7-deaza-8-aza-adenine; 8-aza-7-deazaadenine; 1H-Pyrazolo[3,4-d]pyrimidin-4-amine; 1H-pyrazolo[3,4-d]pyrimidin-4-ylamine; EINECS 219-174-6; pyrazolo[3,4-d]pyrimidin-4-amine; Pyrazoloadenine; Aminopurinol; 4-aminopyrazolo-(3,4-d)pyrimidine; 4-aminopyrazolo[5,4-d]pyrimidine; 4-Aminopyrazolopyrimidine; 1H-Pyrazolo[3,4-d]pyrimidine-4-ylamine 4-Amino-1H-pyrazolo[3,4-d]pyrimidine; Pyrazolo[3,4-d]pyrimidin-4-amin; 4-app; ADENINE ANTIMETABOLITE; MFCD00005688; 3-Piperidineacetic acid, methyl ester, hydrochloride (1:1); 4-AMINOPYRAZOLO{3,4-D}PYRIMIDINE; 1(H)-4-amine-pyrazolo[3,4-d]pyrimidine; 4-Amino pyrazolo[3,4-d]pyrimidine |
| Molecular Formula | C5H5N5 |
| Molecular Weight | 135.13 |
| Purity | 98.00 |
| Density | 1.612g/cm3 |
| Boiling Point | 431.1ºC at 760mmHg |
| Melting Point | >325 °C(lit.) |
| Appearance | beige powder |
| Storage Condition | Store airtight in a cool, dry warehouse. Keep away |
| Packaging | III |
| Application | Pyrazoladine is a potent inhibitor of the RET (recombination during transfection) lung cancer oncoprotein. Pyrazolinedienes show anticancer activity [1][2]. |
| HTC | 2933990090 |
| PubChem ID | 68202 |
| MDL Number | C5H5N5 |
| SMILES | Nc1ncnc2[nH]ncc12 |
| InChI | InChI=1S/C5H5N5/c6-4-3-1-9-10-5(3)8-2-7-4/h1-2H,(H3,6,7,8,9,10) |
| InChI Key | LHCPRYRLDOSKHK-UHFFFAOYSA-N |
| Hazard Symbols | 6.1 |
| MSDS | msds/28399_1_2380_63_4.pdf |
| Bioactivity | Pyrazoloadenine is a potent RET (REarranged during Transfection) lung cancer oncoprotein inhibitor. Pyrazoloadenine shows anticancer activity[1][2]. Related Catalog Research Areas >> Cancer In Vitro Pyrazoloadenine inhibits a wide range of protein kinases such as BTK (Bruton's tyrosine kinase), CDK1/2 (cyclin-dependent kinase 1/2), Src kinase, and RIPK1 (receptor-interacting protein kinase)[1]. Chemical & Physical Properties Density 1.612g/cm3 Boiling Point 431.1ºC at 760mmHg Melting Point >325 °C(lit.) Molecular Formula C5H5N5 Molecular Weight 193.671 Flash Point 244.4ºC Exact Mass 193.086960 PSA 80.48000 LogP 0.51630 InChIKey LHCPRYRLDOSKHK-UHFFFAOYSA-N SMILES Nc1ncnc2[nH]ncc12 Storage condition -20°C Freezer |
| Use of | Pyrazoloadenine is a potent RET (REarranged during Transfection) lung cancer oncoprotein inhibitor. Pyrazoloadenine shows anticancer activity[1][2]. Properties Articles30 Name 4-Aminopyrazolo[3,4-d]pyrimidine Synonym More Synonyms 4-Aminopyrazolo[3,4-d]pyrimidine Biological Activity Description Pyrazoloadenine is a potent RET (REarranged during Transfection) lung cancer oncoprotein inhibitor. Pyrazoloadenine shows anticancer activity[1][2]. Related Catalog Research Areas >> Cancer Chemical & Physical Properties Molecular Formula C5H5N5 Exact Mass 193.086960 PSA 80.48000 LogP 0.51630 InChIKey LHCPRYRLDOSKHK-UHFFFAOYSA-N SMILES Nc1ncnc2[nH]ncc12 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Dangerous Regulations for land transport: 2811 International Dangerous Regulations for sea transport: 2811 International Dangerous Regulations for air transport: 2811 14.2 United Nations shipping name European Land Transport Dangerous Regulations: TOXIC SOLID, ORGANIC, N.O.S. (4-Aminopyrazolo[3,4-d]pyrimidine) IMDG Code: TOXIC SOLID, ORGANIC, N.O.S. (4-Aminopyrazolo[3,4-d]pyrimidine) International air transport hazard regulations: Toxic solid, organic, n.o.s. (4-Aminopyrazolo[3,4-d]pyrimidine) 14.3 Transport hazard categories European Land Transport Danger Regulations: 6.1 International Maritime Transport Danger Regulations: 6.1 International Air Transport Danger Regulations: 6.1 14.4 Package group European Land Transport Danger Regulations: III International Maritime Transport Danger Regulations: III International Air Transport Danger Regulations: III 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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