CAS Number2295-58-1
SynonymsArgobyl; Cospanon; Flopropione; Phloropropiophenone; Gasstenon; EINECS 218-942-8; Ecapron; 2',4',6'-Trihydroxypropiophenone; MFCD00016456; Phlopropiophenone; 1-(2,4,6-trihydroxyphenyl)-1-propanone; Flopropion; Chlonarin
Molecular FormulaC9H10O4
Molecular Weight182.17
Purity98.00%
Density1.372g/cm3
Boiling Point341.7ºC at 760mmHg
Melting Point177°C
Appearancesolid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 2295-58-1 |
| Catalog No. | 2A-9028271 |
| Chinese Name | 夫洛丙酮 |
| Synonyms | Argobyl; Cospanon; Flopropione; Phloropropiophenone; Gasstenon; EINECS 218-942-8; Ecapron; 2',4',6'-Trihydroxypropiophenone; MFCD00016456; Phlopropiophenone; 1-(2,4,6-trihydroxyphenyl)-1-propanone; Flopropion; Chlonarin |
| Molecular Formula | C9H10O4 |
| Molecular Weight | 182.17 |
| Purity | 98.00 |
| Density | 1.372g/cm3 |
| Boiling Point | 341.7ºC at 760mmHg |
| Melting Point | 177°C |
| Appearance | solid |
| Storage Condition | Store under inert gas; avoid moisture (hygroscopic |
| Application | Flopropione is a 5-HT1A receptor antagonist and an inhibitor of catechol-O-methyltransferase (COMT). |
| HTC | 2914501900 |
| PubChem ID | 329794740 |
| MDL Number | MFCD00016456 |
| SMILES | OC1=C(C(CC)=O)C(O)=CC(O)=C1 |
| InChI | 1S/C9H10O4/c1-2-6(11)9-7(12)3-5(10)4-8(9)13/h3-4,10,12-13H,2H2,1H3 |
| InChI Key | PTHLEKANMPKYDB-UHFFFAOYSA-N |
| UNSPSC | 12352200 |
| MSDS | msds/28271_1_2295_58_1.pdf |
| Bioactivity | Flopropione is a 5-HT1A receptor antagonist and also a catechol-o-methyltransferase (COMT) inhibitor. Related Catalog Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor Signaling Pathways >> Metabolic Enzyme/Protease >> COMT Signaling Pathways >> Neuronal Signaling >> COMT Research Areas >> Neurological Disease Target 5-HT1A receptor[1], COMT[2] References [1]. Aso Y et al. Relationship between the crystallization rates of amorphous nifedipine, phenobarbital, and flopropione, and their molecular mobility as measured by their enthalpy relaxation and (1)H NMR relaxation times. J Pharm Sci 89:408-16 (2000). [2]. Cospanon®. (2007). Chemical & Physical Properties Density 1.372g/cm3 Boiling Point 341.7ºC at 760mmHg Melting Point 177°C Molecular Formula C9H10O4 Molecular Weight 182.17300 Flash Point 174.7ºC Exact Mass 182.05800 PSA 77.76000 LogP 1.39610 Vapour Pressure 4E-05mmHg at 25°C Index of Refraction 1.618 InChIKey PTHLEKANMPKYDB-UHFFFAOYSA-N SMILES CCC(=O)c1c(O)cc(O)cc1O |
| Use of | Flopropione is a 5-HT1A receptor antagonist and also a catechol-o-methyltransferase (COMT) inhibitor. Properties Name 1-(2,4,6-trihydroxyphenyl)propan-1-one Synonym More Synonyms Flopropione Biological Activity Description Flopropione is a 5-HT1A receptor antagonist and also a catechol-o-methyltransferase (COMT) inhibitor. Related Catalog Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor Signaling Pathways >> Metabolic Enzyme/Protease >> COMT Signaling Pathways >> Neuronal Signaling >> COMT Research Areas >> Neurological Disease 5-HT1A receptor[1], COMT[2] References [1]. Aso Y et al. Relationship between the crystallization rates of amorphous nifedipine, phenobarbital, and flopropione, and their molecular mobility as measured by their enthalpy relaxation and (1)H NMR relaxation times. J Pharm Sci 89:408-16 (2000). [2]. Cospanon®. (2007). Chemical & Physical Properties Molecular Formula C9H10O4 Exact Mass 182.05800 PSA 77.76000 LogP 1.39610 Index of Refraction 1.618 InChIKey PTHLEKANMPKYDB-UHFFFAOYSA-N |
| Tax Rebate | 9.0% |
| Supervision | none |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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