CAS Number1786-81-8
SynonymsN-(α-Propylaminopropionyl)-o-toluidine hydrochloride; EINECS 217-244-0; PrilocaineHydrochloroide; xylonest; Prilocaine hydrochloride; N-(2-Methylphenyl)-2-(propylamino)propanamidhydrochlorid; propitocaine hydrochloride; N-(2-Methylphenyl)-N-propylalaninamide hydrochloride; prilocainechloride; l-67hydrochloride; N-(2-Methylphenyl)-N-propylalaninamide hydrochloride (1:1); N-(2-Methylphenyl)-2-(propylamino)propanamide hydrochloride; MFCD00079279; Citanest Plain; PRILOCAINE HCL; Propanamide, N-(2-methylphenyl)-2-(propylamino)-, hydrochloride (1:1); Propitocaine HCL; citanesthydrochloride; N-(2-methylphenyl)-N2-propylalaninamide hydrochloride; 2-(Propylamino)-N-(o-tolyl)propionamide Hydrochloride; Prilocaine HC
Molecular FormulaC13H21ClN2O
Molecular Weight256.77
Purity98.00%
Boiling Point85°C 4mm
Melting Point168-170ºC
AppearanceWhite or off-white crystalline powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1786-81-8 |
| Catalog No. | 2A-9027476 |
| Chinese Name | 盐酸丙胺卡因 |
| Synonyms | N-(α-Propylaminopropionyl)-o-toluidine hydrochloride; EINECS 217-244-0; PrilocaineHydrochloroide; xylonest; Prilocaine hydrochloride; N-(2-Methylphenyl)-2-(propylamino)propanamidhydrochlorid; propitocaine hydrochloride; N-(2-Methylphenyl)-N-propylalaninamide hydrochloride; prilocainechloride; l-67hydrochloride; N-(2-Methylphenyl)-N-propylalaninamide hydrochloride (1:1); N-(2-Methylphenyl)-2-(propylamino)propanamide hydrochloride; MFCD00079279; Citanest Plain; PRILOCAINE HCL; Propanamide, N-(2-methylphenyl)-2-(propylamino)-, hydrochloride (1:1); Propitocaine HCL; citanesthydrochloride; N-(2-methylphenyl)-N2-propylalaninamide hydrochloride; 2-(Propylamino)-N-(o-tolyl)propionamide Hydrochloride; Prilocaine HC |
| Molecular Formula | C13H21ClN2O |
| Molecular Weight | 256.77 |
| Purity | 98.00 |
| Boiling Point | 85°C 4mm |
| Melting Point | 168-170ºC |
| Appearance | White or off-white crystalline powder |
| Storage Condition | Refrigerator |
| Application | Prilocaine is a local anesthetic compound. |
| HTC | 2924299090 |
| PubChem ID | 329820155 |
| SMILES | CCCNC(C)C(=O)Nc1ccccc1C.Cl |
| InChI | InChI=1S/C13H20N2O.ClH/c1-4-9-14-11(3)13(16)15-12-8-6-5-7-10(12)2;/h5-8,11,14H,4,9H2,1-3H3,(H,15,16);1H |
| InChI Key | BJPJNTKRKALCPP-UHFFFAOYSA-N |
| Hazard Symbols | transportation |
| Bioactivity | Prilocaine hydrochloride is a local anesthetic of the amino amide type.Target: OthersPrilocaine is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils L?fgren. In its injectable form (trade name Citanest), it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia, for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia (IVRA). In some patients, a metabolite of prilocaine may cause the unusual side effect of methemoglobinemia, which may be treated with methylene blue. Maximum dosage for dental use: 8.0 mg/kg (2.7 mg/lb), with a maximum dose of 500 mg.Eutectic Mixture of Local Anesthetics (EMLA) containing 5% lidocaine and prilocaine in a cream was found to give effective topical analgesia in normal and diseased skin, making it useful for superficial surgery and various other clinical procedures. To be effective, an adequate amount must be applied under occlusion and at the right time before the intervention. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> Na+/K+ ATPase Natural Products >> Others Research Areas >> Others References [1]. Eriksson E. Prilocaine. An experimental study in man of a new local anaesthetic with special regards to efficacy, toxicity and excretion. Acta Chir Scand Suppl. 1966;358:1-82. [2]. Juhlin L, et al. EMLA: a new topical anesthetic. Adv Dermatol. 1990;5:75-91; discussion 92. Chemical & Physical Properties Boiling Point 85°C 4mm Melting Point 168-170ºC Molecular Formula C13H21ClN2O Molecular Weight 256.772 Flash Point 134.3ºC Exact Mass 256.134247 PSA 41.13000 LogP 3.58750 Vapour Pressure 2.05E-05mmHg at 25°C InChIKey BJPJNTKRKALCPP-UHFFFAOYSA-N SMILES CCCNC(C)C(=O)Nc1ccccc1C.Cl Storage condition Refrigerator |
| Use of | Properties Articles36 Name prilocaine hydrochloride Synonym More Synonyms Prilocaine hydrochloride Biological Activity Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> Na+/K+ ATPase Natural Products >> Others Research Areas >> Others References [1]. Eriksson E. Prilocaine. An experimental study in man of a new local anaesthetic with special regards to efficacy, toxicity and excretion. Acta Chir Scand Suppl. 1966;358:1-82. [2]. Juhlin L, et al. EMLA: a new topical anesthetic. Adv Dermatol. 1990;5:75-91; discussion 92. Chemical & Physical Properties Exact Mass 256.134247 PSA 41.13000 LogP 3.58750 InChIKey BJPJNTKRKALCPP-UHFFFAOYSA-N Storage condition Refrigerator |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| 2-Bromo-1-indanone | 1775-27-5 | 2A-9027452 |
| Ethynyltriethylsilane | 1777-03-3 | 2A-9027455 |
| Phenylphosphinic acid | 1779-48-2 | 2A-9027460 |
| 1,2,3,4-Tetrahydroquinaldine | 1780-19-4 | 2A-9027466 |
| Parylene F Dimer | 1785-64-4 | 2A-9027475 |
| 4-Ethynylbenzenesulfonamide | 1788-08-5 | 2A-9027478 |
| (2-Amino-5-chlorophenyl)-cyclohexylmethanone | 1789-30-6 | 2A-9027480 |
| L-Aspartic acid di-tert-butyl ester hydrochloride | 1791-13-5 | 2A-9027482 |
| Dibutylurea | 1792-17-2 | 2A-9027483 |
| Chromeazurol B | 1796-92-5 | 2A-9027489 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS