CAS Number1762-34-1
Synonyms5,5'-Dimethyl-2,2'-bipyridyl; 5,5′-dimethyl-2,2′-bipyridine; 5,5'-dimethyl-bpy; 5,5'-Dimethyl-2,2'-dipyridyl; 5,5'-dimethyl-2,2'-bipy; 6,6'-Di-3-picoline; MFCD01740554; 5,5'-dimethyl-2,2'-bispyridine; Xeglyze; 2,2'-BIPYRIDINE,5,5'-DIMETHYL; 6,6'-Di-3-picolyl; 5,5'-Dimethyl-2,2'-bipyridine; abametapir
Molecular FormulaC12H12N2
Molecular Weight184.24
Purity98%
Density1.1±0.1 g/cm3
Boiling Point315.7±37.0 °C at 760 mmHg
Melting Point114-117 °C (lit.)
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1762-34-1 |
| Catalog No. | 2A-9027435 |
| Chinese Name | 5 5'-二甲基-2,2'-联吡啶 |
| Synonyms | 5,5'-Dimethyl-2,2'-bipyridyl; 5,5′-dimethyl-2,2′-bipyridine; 5,5'-dimethyl-bpy; 5,5'-Dimethyl-2,2'-dipyridyl; 5,5'-dimethyl-2,2'-bipy; 6,6'-Di-3-picoline; MFCD01740554; 5,5'-dimethyl-2,2'-bispyridine; Xeglyze; 2,2'-BIPYRIDINE,5,5'-DIMETHYL; 6,6'-Di-3-picolyl; 5,5'-Dimethyl-2,2'-bipyridine; abametapir |
| Molecular Formula | C12H12N2 |
| Molecular Weight | 184.24 |
| Purity | 98 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 315.7±37.0 °C at 760 mmHg |
| Melting Point | 114-117 °C (lit.) |
| Storage Condition | Sealed and stored in a cool, dry place; away from |
| Application | Abametapir is a metalloproteinase (MMP) inhibitor that targets metalloproteinases that are critical for egg hatching and louse development. Abametapir inhibits the hatching of head and body lice [1][2 |
| HTC | 2933399090 |
| PubChem ID | 24873670 |
| MDL Number | MFCD01740554 |
| SMILES | Cc1ccc(nc1)-c2ccc(C)cn2 |
| InChI | 1S/C12H12N2/c1-9-3-5-11(13-7-9)12-6-4-10(2)8-14-12/h3-8H,1-2H3 |
| InChI Key | PTRATZCAGVBFIQ-UHFFFAOYSA-N |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| Hazard Symbols | transportation |
| MSDS | msds/27435_1_1762_34_1.pdf |
| Bioactivity | Abametapir is a metalloproteinase (MMP) inhibitor which is able to target metalloproteinases critical to egg hatching and louse development. Abametapir can inhibit hatching of both head and body louse[1][2]. Related Catalog Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> MMP In Vitro Abametapir is capable of chelating heavy metal ions, including iron, copper, and zinc, and is therefore able to interact with a range of targets within the insect that require metal co-factors for function, including metalloproteinases[2]. References [1]. Vernon Morrison Bowles, et al. Effect of a New Head Lice Treatment, Abametapir Lotion, 0.74%, on Louse Eggs: A Randomized, Double-Blind Study. Glob Pediatr Health. 2019; 6: 2333794X19831295. [2]. Vernon M. Bowles, et al. Ovicidal Efficacy of Abametapir Against Eggs of Human Head and Body Lice (Anoplura: Pediculidae). J Med Entomol. 2017 Jan; 54(1): 167-172. Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 315.7±37.0 °C at 760 mmHg Melting Point 114-117 °C(lit.) Molecular Formula C12H12N2 Molecular Weight 184.237 Flash Point 119.3±18.1 °C Exact Mass 184.100052 PSA 25.78000 LogP 2.20 Vapour Pressure 0.0±0.6 mmHg at 25°C Index of Refraction 1.566 InChIKey PTRATZCAGVBFIQ-UHFFFAOYSA-N SMILES Cc1ccc(-c2ccc(C)cn2)nc1 |
| Use of | Abametapir is a metalloproteinase (MMP) inhibitor which is able to target metalloproteinases critical to egg hatching and louse development. Abametapir can inhibit hatching of both head and body louse[1][2]. Properties Name 5-methyl-2-(5-methylpyridin-2-yl)pyridine Synonym More Synonyms Xeglyze Biological Activity Description Abametapir is a metalloproteinase (MMP) inhibitor which is able to target metalloproteinases critical to egg hatching and louse development. Abametapir can inhibit hatching of both head and body louse[1][2]. Related Catalog Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> MMP In Vitro Abametapir is capable of chelating heavy metal ions, including iron, copper, and zinc, and is therefore able to interact with a range of targets within the insect that require metal co-factors for function, including metalloproteinases[2]. References [1]. Vernon Morrison Bowles, et al. Effect of a New Head Lice Treatment, Abametapir Lotion, 0.74%, on Louse Eggs: A Randomized, Double-Blind Study. Glob Pediatr Health. 2019; 6: 2333794X19831295. [2]. Vernon M. Bowles, et al. Ovicidal Efficacy of Abametapir Against Eggs of Human Head and Body Lice (Anoplura: Pediculidae). J Med Entomol. 2017 Jan; 54(1): 167-172. Chemical & Physical Properties Molecular Formula C12H12N2 Exact Mass 184.100052 PSA 25.78000 Index of Refraction 1.566 InChIKey PTRATZCAGVBFIQ-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: No dangerous goods IMDG Code: No dangerous goods International Air Transport Dangerous Regulations: No dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special precautions for users No data available The company is not responsible for any damage caused by any operation or contact with the above products. For more terms of use, see invoice or package The reverse side of the mounting strip. |
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