CAS Number1609-47-8
SynonymsDiethyl pyrocarbonate; MFCD00009106; ethoxycarbonyl ethyl carbonate; diethyl dicarbonate; DEP,DEPC,Diethyl dicarbonate; Diethyl pyrocarbonate (DEPC); Diethyl oxydiformate; Ethoxyformic acid anhydride; EINECS 216-542-8
Molecular FormulaO(COOC2H5)2
Molecular Weight162.14
Purity98.00%
Density1.2±0.1 g/cm3
Boiling Point201.3±9.0 °C at 760 mmHg
Appearancecolorless liquid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1609-47-8 |
| Catalog No. | 2A-9027118 |
| Chinese Name | 焦碳酸二乙酯 |
| Synonyms | Diethyl pyrocarbonate; MFCD00009106; ethoxycarbonyl ethyl carbonate; diethyl dicarbonate; DEP,DEPC,Diethyl dicarbonate; Diethyl pyrocarbonate (DEPC); Diethyl oxydiformate; Ethoxyformic acid anhydride; EINECS 216-542-8 |
| Molecular Formula | O(COOC2H5)2 |
| Molecular Weight | 162.14 |
| Purity | 98.00 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 201.3±9.0 °C at 760 mmHg |
| Appearance | colorless liquid |
| Water Solubility | slow decomposition |
| Storage Condition | Store under dry inert gas, keep container sealed, |
| Packaging | III |
| Application | Diethylpyrocarbonate is a potent non-specific chemical inhibitor of RNase. Diethylpyrocarbonate is useful in vitro as a relatively specific agent that binds histidine imidazole. Diethylpyrocarbonate i |
| HTC | 2920909090 |
| PubChem ID | 329830217 |
| SMILES | CCOC(=O)OC(=O)OCC |
| InChI | InChI=1S/C6H10O5/c1-3-9-5(7)11-6(8)10-4-2/h3-4H2,1-2H3 |
| InChI Key | FFYPMLJYZAEMQB-UHFFFAOYSA-N |
| Hazard Symbols | 6.1(b) |
| Bioactivity | Diethyl pyrocarbonate is a potent, non-specific chemical inhibitor of RNase. Diethyl pyrocarbonate has been useful in vitro as an agent relatively specific for binding to imidazole of histidine. Diethyl pyrocarbonate inhibits central chemosensitivity in rabbits. Diethyl pyrocarbonate can modify Ser, Thr, His and Tyr residues[1]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease References [1]. E E Nattie. Diethyl pyrocarbonate (an imidazole binding substance) inhibits rostral VLM CO2 sensitivity. J Appl Physiol (1985). 1986 Sep;61(3):843-50. Chemical & Physical Properties Density 1.2±0.1 g/cm3 Boiling Point 201.3±9.0 °C at 760 mmHg Molecular Formula C6H10O5 Molecular Weight 162.141 Flash Point 69.4±0.0 °C Exact Mass 162.052826 PSA 61.83000 LogP 1.48 Vapour Pressure 0.3±0.4 mmHg at 25°C Index of Refraction 1.413 InChIKey FFYPMLJYZAEMQB-UHFFFAOYSA-N SMILES CCOC(=O)OC(=O)OCC Storage condition 2-8°C Stability Combustible. Unstable - readily decomposes. Incompatible with strong oxidizing agents, strong acids, strong reducing agents, strong bases, ammonia. Water Solubility slow decomposition |
| Use of | Diethyl pyrocarbonate is a potent, non-specific chemical inhibitor of RNase. Diethyl pyrocarbonate has been useful in vitro as an agent relatively specific for binding to imidazole of histidine. Diethyl pyrocarbonate inhibits central chemosensitivity in rabbits. Diethyl pyrocarbonate can modify Ser, Thr, His and Tyr residues[1]. Properties Articles196 Name diethyl pyrocarbonate Synonym More Synonyms Diethyl pyrocarbonate Biological Activity Description Diethyl pyrocarbonate is a potent, non-specific chemical inhibitor of RNase. Diethyl pyrocarbonate has been useful in vitro as an agent relatively specific for binding to imidazole of histidine. Diethyl pyrocarbonate inhibits central chemosensitivity in rabbits. Diethyl pyrocarbonate can modify Ser, Thr, His and Tyr residues[1]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease References [1]. E E Nattie. Diethyl pyrocarbonate (an imidazole binding substance) inhibits rostral VLM CO2 sensitivity. J Appl Physiol (1985). 1986 Sep;61(3):843-50. Chemical & Physical Properties Molecular Formula C6H10O5 Exact Mass 162.052826 PSA 61.83000 Index of Refraction 1.413 InChIKey FFYPMLJYZAEMQB-UHFFFAOYSA-N SMILES CCOC(=O)OC(=O)OCC Stability Combustible. Unstable - readily decomposes. Incompatible with strong oxidizing agents, strong acids, strong reducing agents, strong bases, ammonia. Water Solubility slow decomposition |
| Tax Rebate | 9.0% |
| Supervision | none |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available If applicable, the chemical meets the requirements of the Regulations on the Safety Management of Hazardous Chemicals (adopted by the State Council on January 9, 2002). |
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