CAS Number1197-18-8
Synonyms(1R,2R)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride (1:1); trans-Tramadol hydrochloride; Amstat; trans-4-(Aminomethyl)cyclohexane-carboxylic acid; Cyclohexanol, 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)-, (1R,2R)-, hydrochloride (1:1); UNII:9N7R477WCK; Tramadol hydrochloride; tranexamic acid; trans-4-(Aminomethyl)-1-cyclohexanecarboxylic acid; (1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride; trans-4-(Aminomethyl)cyclohexane-1-carboxylic acid; Tramadol HCL; (1R,2R)-2-[(diméthylamino)méthyl]-1-(3-méthoxyphényl)cyclohexanol chlorhydrate; AMCA,AMCHA,HAKU; cis-Tranexamic Acid; cis-4-(Aminomethyl)-1-cyclohexanecarboxylicacid; (+)-tramadol hydrochloride; CIS-4-(AMINOMETHYL)CYCLOHEXANECARBOXYLICACID; trans-4-(Aminomethyl)cyclohexaneca
Molecular FormulaH2NCH2C6H10CO2H
Molecular Weight157.21
Purity98.00%
Density1.1±0.1 g/cm3
Boiling Point300.2±15.0 °C at 760 mmHg
Melting Point>300 °C(lit.)
AppearanceWhite crystalline powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1197-18-8 |
| Catalog No. | 2A-9026453 |
| Chinese Name | 凝血酸，氨甲环酸 |
| Synonyms | (1R,2R)-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride (1:1); trans-Tramadol hydrochloride; Amstat; trans-4-(Aminomethyl)cyclohexane-carboxylic acid; Cyclohexanol, 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)-, (1R,2R)-, hydrochloride (1:1); UNII:9N7R477WCK; Tramadol hydrochloride; tranexamic acid; trans-4-(Aminomethyl)-1-cyclohexanecarboxylic acid; (1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol hydrochloride; trans-4-(Aminomethyl)cyclohexane-1-carboxylic acid; Tramadol HCL; (1R,2R)-2-[(diméthylamino)méthyl]-1-(3-méthoxyphényl)cyclohexanol chlorhydrate; AMCA,AMCHA,HAKU; cis-Tranexamic Acid; cis-4-(Aminomethyl)-1-cyclohexanecarboxylicacid; (+)-tramadol hydrochloride; CIS-4-(AMINOMETHYL)CYCLOHEXANECARBOXYLICACID; trans-4-(Aminomethyl)cyclohexaneca |
| Molecular Formula | H2NCH2C6H10CO2H |
| Molecular Weight | 157.21 |
| Purity | 98.00 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 300.2±15.0 °C at 760 mmHg |
| Melting Point | >300 °C(lit.) |
| Appearance | White crystalline powder |
| Water Solubility | 1G/6ML |
| Storage Condition | Store sealed in a cool and dark place. |
| Packaging | II |
| Application | Tranexamic acid (Transamin) blocks the lysine binding site of plasmin and the plasminogen fragment derived from elastase. |
| HTC | 2922499990 |
| PubChem ID | 145436 |
| SMILES | NCC1CCC(CC1)C(O)=O |
| InChI | InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11) |
| InChI Key | InChIKey=GYDJEQRTZSCIOI-UHFFFAOYSA-N |
| Hazard Symbols | 3 |
| Bioactivity | Tranexamic acid (Transamin) is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM. Target: OthersTranexamic acid is a synthetic derivative of the amino acid lysine. Tranexamic acid is frequently used in surgeries with high risk of blood loss such as cardiac, liver, vascular and large orthopedic procedures. Its oral form is now being evaluated for use in outpatient conditions involving heavy bleeding.Toxicity/Adverse event: Rare in general, including gastrointestinal effects, dizziness, fatigue, headache, and hypersensitivity reactions. Use of tranexamic acid has a potential risk of thrombosis. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Cardiovascular Disease References [1]. Bhat A, et al. Tranexamic acid overdosage-induced generalized seizure in renal failure. Saudi J Kidney Dis Transpl. 2014 Jan-Feb;25(1):130-2. [2]. Couturier R, et al. Continuous or discontinuous tranexamic acid effectively inhibits fibrinolysis in children undergoing cardiac surgery with cardiopulmonary bypass. Blood Coagul Fibrinolysis. 2014 Jan 13. Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 300.2±15.0 °C at 760 mmHg Melting Point >300 °C(lit.) Molecular Formula C8H15NO2 Molecular Weight 157.210 Flash Point 135.4±20.4 °C Exact Mass 157.110275 PSA 63.32000 LogP 0.31 Vapour Pressure 0.0±1.3 mmHg at 25°C Index of Refraction 1.497 Water Solubility 1G/6ML |
| Use of | Properties Articles144 Name tranexamic acid Synonym More Synonyms Tranexamic acid Biological Activity Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Cardiovascular Disease References [1]. Bhat A, et al. Tranexamic acid overdosage-induced generalized seizure in renal failure. Saudi J Kidney Dis Transpl. 2014 Jan-Feb;25(1):130-2. [2]. Couturier R, et al. Continuous or discontinuous tranexamic acid effectively inhibits fibrinolysis in children undergoing cardiac surgery with cardiopulmonary bypass. Blood Coagul Fibrinolysis. 2014 Jan 13. Chemical & Physical Properties Molecular Formula C8H15NO2 Exact Mass 157.110275 PSA 63.32000 Index of Refraction 1.497 Water Solubility 1G/6ML |
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| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available See reverse side of invoice or packing slip. |
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