CAS Number1147-23-5
Synonyms5-Iodo-D-cytidine; 5-iodo-cytidine; iodocytidine; 1-D-Ribofuranosyl-5-iodocytosine; 5-IC; 5-Iodcytidin; 5-Jod-cytidin; MFCD00056070
Molecular FormulaC9H12IN3O5
Molecular Weight369.12
Purity98.00%
Density2.52 g/cm3
Boiling Point565.5ºCat 760 mmHg
AppearanceCrystalline or Powder | White to Off-white
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1147-23-5 |
| Catalog No. | 2A-9026333 |
| Chinese Name | 5-碘胞啶 |
| Synonyms | 5-Iodo-D-cytidine; 5-iodo-cytidine; iodocytidine; 1-D-Ribofuranosyl-5-iodocytosine; 5-IC; 5-Iodcytidin; 5-Jod-cytidin; MFCD00056070 |
| Molecular Formula | C9H12IN3O5 |
| Molecular Weight | 369.12 |
| Purity | 98.00 |
| Density | 2.52 g/cm3 |
| Boiling Point | 565.5ºCat 760 mmHg |
| Appearance | Crystalline or Powder | White to Off-white |
| Storage Condition | -20°C |
| Application | 5-iodocytidine (5-iodo-D-cytidine) is a purine nucleoside analog. Purine nucleoside analogues have broad antitumor activity and target indolent lymphoid malignancies. The anti-cancer mechanism in this |
| HTC | 2934999090 |
| PubChem ID | 10253579 |
| SMILES | Nc1nc(=O)n(C2OC(CO)C(O)C2O)cc1I |
| InChI | InChI=1S/C9H12IN3O5/c10-3-1-13(9(17)12-7(3)11)8-6(16)5(15)4(2-14)18-8/h1,4-6,8,14-16H,2H2,(H2,11,12,17)/t4-,5-,6-,8-/m1/s1 |
| InChI Key | LQQGJDJXUSAEMZ-UAKXSSHOSA-N |
| Use of | 5-Iodo-cytidine (5-Iodo-D-cytidine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Properties Name 5-Iodocytidine Synonym More Synonyms 5-Iodocytidine Biological Activity Description 5-Iodo-cytidine (5-Iodo-D-cytidine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Related Catalog Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others References [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. Chemical & Physical Properties Molecular Formula C9H12IN3O5 Exact Mass 368.98200 PSA 130.83000 Appearance of Characters Crystalline or Powder | White to Off-white Index of Refraction 1.85 InChIKey LQQGJDJXUSAEMZ-UAKXSSHOSA-N SMILES Nc1nc(=O)n(C2OC(CO)C(O)C2O)cc1I Safety Information Hazard Codes Xi HS Code 2934999090 Synthetic Route Total: 1 Page CAS#:65-46-3 5-Iodocytidine CAS#:1147-23-5 Literature: Paolini, Lisa; Petricci, Elena; Corelli, Federico; Botta, Maurizio Synthesis, 2003 , # 7 p. 1039 - 1042 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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